Mannich-Type Reaction with TrifluoromethylatedN,O-Hemiacetal:  Facile Preparation of β-Amino-β-trifluoromethyl Carbonyl Compounds

Jun Takaya; Hirotaka Kagoshima; Takahiko Akiyama

doi:10.1021/ol005812e

Mannich-Type Reaction with TrifluoromethylatedN,O-Hemiacetal: Facile Preparation of β-Amino-β-trifluoromethyl Carbonyl Compounds

Organic Letters ◽

10.1021/ol005812e ◽

2000 ◽

Vol 2 (11) ◽

pp. 1577-1579 ◽

Cited By ~ 53

Author(s):

Jun Takaya ◽

Hirotaka Kagoshima ◽

Takahiko Akiyama

Keyword(s):

Carbonyl Compounds ◽

Type Reaction ◽

Facile Preparation

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ChemInform Abstract: Mannich-Type Reaction with Trifluoromethylated N,O-Hemiacetal: Facile Preparation of β-Amino-β-trifluoromethyl Carbonyl Compounds.

ChemInform ◽

10.1002/chin.200037068 ◽

2000 ◽

Vol 31 (37) ◽

pp. no-no

Author(s):

Jun Takaya ◽

Hirotaka Kagoshima ◽

Takahiko Akiyama

Keyword(s):

Carbonyl Compounds ◽

Type Reaction ◽

Facile Preparation

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Basic Functionalized Ionic Liquid Catalyzed One-pot Mannich-type Reaction: Three Component Synthesis of β-Amino Carbonyl Compounds

Monatshefte für Chemie - Chemical Monthly ◽

10.1007/s00706-007-0767-2 ◽

2007 ◽

Vol 138 (11) ◽

pp. 1195-1198 ◽

Cited By ~ 46

Author(s):

Kai Gong ◽

Dong Fang ◽

Hua-Lan Wang ◽

Zu-Liang Liu

Keyword(s):

Ionic Liquid ◽

Carbonyl Compounds ◽

One Pot ◽

Functionalized Ionic Liquid ◽

Type Reaction

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ChemInform Abstract: Facile Preparation of Allylzinc Species from Allylboronates and Zinc Amide via a Boron-to-Zinc Exchange Process and Their Reactions with Carbonyl Compounds, Imines and Hydrazones.

ChemInform ◽

10.1002/chin.201306035 ◽

2013 ◽

Vol 44 (6) ◽

pp. no-no

Author(s):

Yi Cui ◽

Yasuhiro Yamashita ◽

Shu Kobayashi

Keyword(s):

Carbonyl Compounds ◽

Exchange Process ◽

Facile Preparation

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ChemInform Abstract: Ring-Opening Aldol-Type Reaction of 2,2-Dialkoxycyclopropanecarboxylic Esters with Carbonyl Compounds. Part 3. The Diastereoselective Synthesis of 2,3,4-Trisubstituted γ-Lactones.

ChemInform ◽

10.1002/chin.199401185 ◽

2010 ◽

Vol 25 (1) ◽

pp. no-no

Author(s):

S. SHIMADA ◽

Y. HASHIMOTO ◽

K. SAIGO

Keyword(s):

Carbonyl Compounds ◽

Ring Opening ◽

Diastereoselective Synthesis ◽

Type Reaction

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One-pot Mannich-Type Reaction In Water: HBF4 Catalyzed Condensation of Aldehydes, Amines, and Silyl Enolates for the Synthesis of β-Amino Carbonyl Compounds

Synlett ◽

10.1055/s-1999-2872 ◽

1999 ◽

Vol 1999 (9) ◽

pp. 1426-1428 ◽

Cited By ~ 53

Author(s):

Takahiko Akiyama ◽

Jun Takaya ◽

Hirotaka Kagoshima

Keyword(s):

Carbonyl Compounds ◽

One Pot ◽

Type Reaction ◽

Reaction In Water

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ChemInform Abstract: An Efficient and General Method for the Reformatsky-Type Reaction of Chlorodifluoromethyl Ketones with Carbonyl Compounds Giving α,α-Difluoro-β-hydroxy Ketones.

ChemInform ◽

10.1002/chin.199025061 ◽

1990 ◽

Vol 21 (25) ◽

Author(s):

M. KUROBOSHI ◽

T. ISHIHARA

Keyword(s):

Carbonyl Compounds ◽

Type Reaction ◽

Hydroxy Ketones ◽

General Method

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A facile preparation of ethanolamines by direct irradiation of some carbonyl compounds in N,N-dimethylaniline

Tetrahedron Letters ◽

10.1016/s0040-4039(01)01784-1 ◽

2001 ◽

Vol 42 (47) ◽

pp. 8315-8317 ◽

Cited By ~ 9

Author(s):

Sung Sik Kim ◽

Yoon Jung Mah ◽

Ae Rhan Kim

Keyword(s):

Carbonyl Compounds ◽

Direct Irradiation ◽

Facile Preparation

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ChemInform Abstract: Facile Routes to Boron Enolates. Et3B-Mediated Reformatsky Type Reaction and Three Components Coupling Reaction of Alkyl Iodides, Methyl Vinyl Ketone, and Carbonyl Compounds.

ChemInform ◽

10.1002/chin.198830134 ◽

1988 ◽

Vol 19 (30) ◽

Author(s):

K. NOZAKI ◽

K. OSHIMA ◽

K. UTIMOTO

Keyword(s):

Carbonyl Compounds ◽

Coupling Reaction ◽

Vinyl Ketone ◽

Methyl Vinyl Ketone ◽

Methyl Vinyl ◽

Type Reaction ◽

Alkyl Iodides ◽

Three Components

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NbCl5-Catalyzed One-Pot Mannich-Type Reaction: Three Component Synthesis of β-Amino Carbonyl Compounds.

ChemInform ◽

10.1002/chin.200726081 ◽

2007 ◽

Vol 38 (26) ◽

Author(s):

Rui Wang ◽

Bo-gang Li ◽

Tai-kun Huang ◽

Lin Shi ◽

Xiao-xia Lu

Keyword(s):

Carbonyl Compounds ◽

One Pot ◽

Type Reaction

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The intramolecular tandem Michael/Mannich-type reaction of α,β-unsaturated carbonyl compounds with acyliminium ions provides access to chiral indolizidines

Tetrahedron Asymmetry ◽

10.1016/j.tetasy.2007.06.009 ◽

2007 ◽

Vol 18 (13) ◽

pp. 1533-1539 ◽

Cited By ~ 9

Author(s):

Yuji Koseki ◽

Koji Fujino ◽

Ai Takeshita ◽

Hiroto Sato ◽

Tatsuo Nagasaka

Keyword(s):

Carbonyl Compounds ◽

Type Reaction ◽

Acyliminium Ions

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