Biohalogenation: Nature’s Way to Synthesize Halogenated Metabolites†

2009 ◽  
Vol 72 (3) ◽  
pp. 540-553 ◽  
Author(s):  
Claudia Wagner ◽  
Mustafa El Omari ◽  
Gabriele M. König
Keyword(s):  
Halogenated Metabolites

Halogenated metabolites from Irish Osmundea spp. – a three course meal for Aplysia sp.

Planta Medica ◽  
2016 ◽  
Vol 81 (S 01) ◽  
pp. S1-S381
Author(s):  
S Soldatou ◽  
RM Young ◽  
S Heesch ◽  
BJ Baker
Keyword(s):  
Halogenated Metabolites

scholarly journals Exploration of marine natural resources in Indonesia and development of efficient strategies for the production of microbial halogenated metabolites

2021 ◽  
Author(s):  
Hiroyuki Yamazaki
Keyword(s):  
Natural Product ◽  
Protein Tyrosine Phosphatase ◽  
Biological Activities ◽  
Tyrosine Phosphatase ◽  
Osteoblastic Differentiation ◽  
Biological Properties ◽  
Protein Tyrosine Phosphatase 1B ◽  
Productive Performance ◽  
Halogenated Metabolites ◽  
Morphogenetic Protein

AbstractNature is a prolific source of organic products with diverse scaffolds and biological activities. The process of natural product discovery has gradually become more challenging, and advances in novel strategic approaches are essential to evolve natural product chemistry. Our focus has been on surveying untouched marine resources and fermentation to enhance microbial productive performance. The first topic is the screening of marine natural products isolated from Indonesian marine organisms for new types of bioactive compounds, such as antineoplastics, antimycobacterium substances, and inhibitors of protein tyrosine phosphatase 1B, sterol O-acyl-transferase, and bone morphogenetic protein-induced osteoblastic differentiation. The unique biological properties of marine organohalides are discussed herein and attempts to efficiently produce fungal halogenated metabolites are documented. This review presents an overview of our recent work accomplishments based on the MONOTORI study. Graphic abstract

Cytotoxic Halogenated Metabolites from the Brazilian Red AlgaLaurencia catarinensis

2010 ◽  
Vol 73 (1) ◽  
pp. 27-32 ◽  
Author(s):  
Cintia Lhullier ◽  
Miriam Falkenberg ◽  
Efstathia Ioannou ◽  
Antonio Quesada ◽  
Panagiota Papazafiri ◽  
...  
Keyword(s):  
Halogenated Metabolites

Novel Halogenated Metabolites from the MalaysianLaurenciapannosa1

2001 ◽  
Vol 64 (5) ◽  
pp. 597-602 ◽  
Author(s):  
Minoru Suzuki ◽  
Motonari Daitoh ◽  
Charles Santhanaraju Vairappan ◽  
Tsuyoshi Abe ◽  
Michio Masuda
Keyword(s):  
Halogenated Metabolites

Three halogenated metabolites fromLaurencia obtusa

1990 ◽  
Vol 29 (10) ◽  
pp. 3193-3196 ◽  
Author(s):  
Saif-Eldin N. Ayyad ◽  
Abdel-Aziz M. Dawidar ◽  
Hanwellage W. Dias ◽  
R. Alan Howie ◽  
Jsmin Jakupovic ◽  
...  
Keyword(s):  
Halogenated Metabolites

Halogenated Metabolites of the Red Alga Plocamium cruciferum

1979 ◽  
Vol 32 (11) ◽  
pp. 2545 ◽  
Author(s):  
P Bates ◽  
JW Blunt ◽  
MP Hartshorn ◽  
AJ Jones ◽  
MHG Munro ◽  
...  
Keyword(s):  
Fatty Acid Methyl Esters ◽  
Methyl Esters ◽  
Complex Mixture ◽  
Red Alga ◽  
Organic Extract ◽  
X Ray ◽  
X Ray Crystallography ◽  
Halogenated Metabolites ◽  
Acid Methyl ◽  
Absolute Stereochemistry

The organic extract of Plocamium cruciferum gave a complex mixture of fatty acid methyl esters (26%), the tribromotrichloroalkene (12),(7%), n-heptadecane (0.4%), phytol(12%) and the unusual hydroxy bisnor-monoterpene (15) (43%). The absolute stereochemistry of the polyhalogenated alkene (12) was established by X-ray crystallography.

Variations in the halogenated metabolites of Laurencia obtusa from eastern Sicily

1981 ◽  
Vol 9 (4) ◽  
pp. 241-246 ◽  
Author(s):  
Salvatore Caccamese ◽  
Roberto Azzolina ◽  
Rosa Maria Toscano ◽  
Kenneth L. Rinehart
Keyword(s):  
Halogenated Metabolites

Halogenated Metabolites from the New Okinawan Red AlgaLaurencia yonaguniensis

2002 ◽  
Vol 65 (3) ◽  
pp. 395-398 ◽  
Author(s):  
Yoshinori Takahashi ◽  
Motonari Daitoh ◽  
Minoru Suzuki ◽  
Tsuyoshi Abe ◽  
Michio Masuda
Keyword(s):  
Halogenated Metabolites
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