A Thiopyranchromenone and Other Chromone Derivatives from an Endolichenic Fungus, Preussia africana

2012 ◽  
Vol 75 (2) ◽  
pp. 230-237 ◽  
Author(s):  
Fan Zhang ◽  
Li Li ◽  
Shubin Niu ◽  
Yikang Si ◽  
Liangdong Guo ◽  
...  
Keyword(s):  
Chromone Derivatives ◽  
Endolichenic Fungus

scholarly journals New phenol and chromone derivatives from the endolichenic fungus Daldinia species and their antiviral activities

RSC Advances ◽  
2021 ◽  
Vol 11 (36) ◽  
pp. 22489-22494
Author(s):  
Dewu Zhang ◽  
Guowei Gu ◽  
Bingyuan Zhang ◽  
Yujia Wang ◽  
Jinglin Bai ◽  
...  
Keyword(s):  
Chromone Derivatives ◽  
Endolichenic Fungus ◽  
Antiviral Activities

Eight phenols including three new ones (1–3) and four chromones including two new ones (9 and 10) were isolated from endolichenic fungus Daldinia sp. CPCC 400770, and some of them showed significant antiviral activities.

Synthesis of novel 3-(substituted phenyl) chromone derivatives and their anti-tumor activities

2010 ◽  
Vol 30 (8) ◽  
pp. 864-869
Author(s):  
Huan-wen DONG ◽  
Yue-li ZHANG ◽  
Jue-ying LIU ◽  
Zhen-hua QUAN ◽  
Tie-jun LI ◽  
...  
Keyword(s):  
Chromone Derivatives

scholarly journals Rare Chromone Derivatives from the Marine-Derived Penicillium citrinum with Anti-Cancer and Anti-Inflammatory Activities

Marine Drugs ◽  
2021 ◽  
Vol 19 (1) ◽  
pp. 25
Author(s):  
Yi-Cheng Chu ◽  
Chun-Hao Chang ◽  
Hsiang-Ruei Liao ◽  
Ming-Jen Cheng ◽  
Ming-Der Wu ◽  
...  
Keyword(s):  
A549 Cells ◽  
Penicillium Citrinum ◽  
Signaling Cascades ◽  
Human Neutrophils ◽  
Cytotoxic Activities ◽  
Western Blot Assay ◽  
Chromone Derivatives ◽  
Anti Cancer ◽  
Ic50 Values ◽  
Induced Apoptosis

Three new and rare chromone derivatives, epiremisporine C (1), epiremisporine D (2), and epiremisporine E (3), were isolated from marine-derived Penicillium citrinum, together with four known compounds, epiremisporine B (4), penicitrinone A (5), 8-hydroxy-1-methoxycarbonyl-6-methylxanthone (6), and isoconiochaetone C (7). Among the isolated compounds, compounds 2–5 significantly decreased fMLP-induced superoxide anion generation by human neutrophils, with IC50 values of 6.39 ± 0.40, 8.28 ± 0.29, 3.62 ± 0.61, and 2.67 ± 0.10 μM, respectively. Compounds 3 and 4 exhibited cytotoxic activities with IC50 values of 43.82 ± 6.33 and 32.29 ± 4.83 μM, respectively, against non-small lung cancer cell (A549), and Western blot assay confirmed that compounds 3 and 4 markedly induced apoptosis of A549 cells, through Bcl-2, Bax, and caspase 3 signaling cascades.

Chromene and chromone derivatives as liver X receptors modulators from a marine-derived Pestalotiopsis neglecta fungus

2021 ◽  
pp. 104927
Author(s):  
Zhi Liang ◽  
Tanwei Gu ◽  
Jianjiao Wang ◽  
Jianglian She ◽  
Yuxiu Ye ◽  
...  
Keyword(s):  
Liver X Receptors ◽  
Chromone Derivatives ◽  
X Receptors ◽  
Pestalotiopsis Neglecta

Effects of substituent pattern on the intracellular target of antiproliferative benzo[b]thiophenyl chromone derivatives

2021 ◽  
pp. 113578
Author(s):  
Yohei Saito ◽  
Yukako Taniguchi ◽  
Sachika Hirazawa ◽  
Yuta Miura ◽  
Hiroyuki Tsurimoto ◽  
...  
Keyword(s):  
Chromone Derivatives ◽  
Intracellular Target

Tetramic Acids and Pyridone Alkaloids from the Endolichenic Fungus Tolypocladium cylindrosporum

2015 ◽  
Vol 78 (9) ◽  
pp. 2155-2160 ◽  
Author(s):  
Xiao-Bin Li ◽  
Lin Li ◽  
Rong-Xiu Zhu ◽  
Wei Li ◽  
Wen-Qiang Chang ◽  
...  
Keyword(s):  
Tetramic Acids ◽  
Endolichenic Fungus

Two new 2-(2-phenethyl)chromone derivatives from agarwood of Aquilaria walla and their cytotoxicity

2021 ◽  
Vol 42 ◽  
pp. 36-40
Author(s):  
Yue-Yue Wang ◽  
Hao Wang ◽  
Cheng-Neng Mi ◽  
Wei Li ◽  
Cui-Juan Gai ◽  
...  
Keyword(s):  
Chromone Derivatives

Chromone Derivatives Bearing Pyridinium Moiety as Multi-Target-Directed Ligands against Alzheimer’s disease

2021 ◽  
pp. 104750
Author(s):  
Shahin Abdpour ◽  
Leili Jalili-Baleh ◽  
Hamid Nadri ◽  
Hamid Forootanfar ◽  
Syed Nasir Abbas Bukhari ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Chromone Derivatives

scholarly journals New Chromones from a Marine-Derived Fungus, Arthrinium sp., and Their Biological Activity

Molecules ◽  
2018 ◽  
Vol 23 (8) ◽  
pp. 1982 ◽  
Author(s):  
Jie Bao ◽  
Fei He ◽  
Jin-Hai Yu ◽  
Huijuan Zhai ◽  
Zhi-Qiang Cheng ◽  
...  
Keyword(s):  
Biological Activity ◽  
Deep Sea ◽  
Spectroscopic Data ◽  
Radical Scavenging ◽  
Antioxidant Property ◽  
Electronic Circular Dichroism ◽  
Chromone Derivatives ◽  
Ic50 Values ◽  
Ester Method ◽  
The Absolute

Five new chromone derivatives, arthones A–E (1–5), together with eight known biogenetically related cometabolites (6–13), were isolated from a deep-sea-derived fungus Arthrinium sp. UJNMF0008. Their structures were assigned by detailed analyses of spectroscopic data, while the absolute configurations of 1 and 5 were established by electronic circular dichroism (ECD) calculations and that of 2 was determined by modified Mosher ester method. Compounds 3 and 8 exhibited potent antioxidant property with DPPH and ABTS radical scavenging activities, with IC50 values ranging from 16.9 to 18.7 μM. Meanwhile, no compounds indicated obvious bioactivity in our antimicrobial and anti-inflammatory assays at 50.0 μM.

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