Clavicipitaceous Fungi Associated with Ergoline Alkaloid-Containing Convolvulaceae

2007 ◽  
Vol 70 (12) ◽  
pp. 1955-1960 ◽  
Author(s):  
Mahalia A. Ahimsa-Müller ◽  
Anne Markert ◽  
Sabine Hellwig ◽  
Volker Knoop ◽  
Ulrike Steiner ◽  
...  
Keyword(s):  
Clavicipitaceous Fungi

scholarly journals Phylogenetic classification of Cordyceps and the clavicipitaceous fungi

2007 ◽  
Vol 57 ◽  
pp. 5-59 ◽  
Author(s):  
Gi-Ho Sung ◽  
Nigel L. Hywel-Jones ◽  
Jae-Mo Sung ◽  
J. Jennifer Luangsa-ard ◽  
Bhushan Shrestha ◽  
...  
Keyword(s):  
Phylogenetic Classification ◽  
Clavicipitaceous Fungi

scholarly journals Structures of the Mating-Type Loci of Cordyceps takaomontana

2003 ◽  
Vol 69 (8) ◽  
pp. 5019-5022 ◽  
Author(s):  
Eiji Yokoyama ◽  
Kenzo Yamagishi ◽  
Akira Hara
Keyword(s):  
Mating Type ◽  
Nucleotide Sequences ◽  
The Other ◽  
Other Hand ◽  
Mating Type Genes ◽  
Clavicipitaceous Fungi

ABSTRACT Nucleotide sequences of the mating-type loci MAT1-1 and MAT1-2 of Cordyceps takaomontana were determined, which is the first such report for the clavicipitaceous fungi. MAT1-1 contains two mating-type genes, MAT1-1-1 and MAT1-1-2, but MAT1-1-3 could not be found. On the other hand, MAT1-2 has MAT1-2-1. A pseudogene of MAT1-1-1 is located next to MAT1-2.

scholarly journals An Old Yellow Enzyme Gene Controls the Branch Point between Aspergillus fumigatus and Claviceps purpurea Ergot Alkaloid Pathways

2010 ◽  
Vol 76 (12) ◽  
pp. 3898-3903 ◽  
Author(s):  
Christine M. Coyle ◽  
Johnathan Z. Cheng ◽  
Sarah E. O'Connor ◽  
Daniel G. Panaccione
Keyword(s):  
Aspergillus Fumigatus ◽  
Ergot Alkaloid ◽  
Ergot Alkaloids ◽  
Aldehyde Group ◽  
Ring Structure ◽  
Ring Closure ◽  
Claviceps Purpurea ◽  
Wild Type ◽  
Old Yellow Enzyme ◽  
Clavicipitaceous Fungi

ABSTRACT Ergot fungi in the genus Claviceps and several related fungal groups in the family Clavicipitaceae produce toxic ergot alkaloids. These fungi produce a variety of ergot alkaloids, including clavines as well as lysergic acid derivatives. Ergot alkaloids are also produced by the distantly related, opportunistic human pathogen Aspergillus fumigatus. However, this fungus produces festuclavine and fumigaclavines A, B, and C, which collectively differ from clavines of clavicipitaceous fungi in saturation of the last assembled of four rings in the ergoline ring structure. The two lineages are hypothesized to share early steps of the ergot alkaloid pathway before diverging at some point after the synthesis of the tricyclic intermediate chanoclavine-I. Disruption of easA, a gene predicted to encode a flavin-dependent oxidoreductase of the old yellow enzyme class, in A. fumigatus led to accumulation of chanoclavine-I and chanoclavine-I-aldehyde. Complementation of the A. fumigatus easA mutant with a wild-type allele from the same fungus restored the wild-type profile of ergot alkaloids. These data demonstrate that the product of A. fumigatus easA is required for incorporation of chanoclavine-I-aldehyde into more-complex ergot alkaloids, presumably by reducing the double bond conjugated to the aldehyde group, thus facilitating ring closure. Augmentation of the A. fumigatus easA mutant with a homologue of easA from Claviceps purpurea resulted in accumulation of ergot alkaloids typical of clavicipitaceous fungi (agroclavine, setoclavine, and its diastereoisomer isosetoclavine). These data indicate that functional differences in the easA-encoded old yellow enzymes of A. fumigatus and C. purpurea result in divergence of their respective ergot alkaloid pathways.

Molecular and morphological studies ofPaecilomyces sinensisreveal a new clade in clavicipitaceous fungi and its new systematic position

2012 ◽  
Vol 10 (2) ◽  
pp. 221-232 ◽  
Author(s):  
Wen-Jing Wang ◽  
Xiao-Liang Wang ◽  
Yi Li ◽  
Sheng-Rong Xiao ◽  
Ryan M. Kepler ◽  
...  
Keyword(s):  
Systematic Position ◽  
Morphological Studies ◽  
Clavicipitaceous Fungi

scholarly journals The Key Role of Peltate Glandular Trichomes in Symbiota Comprising Clavicipitaceous Fungi of the Genus Periglandula and Their Host Plants

Toxins ◽  
2015 ◽  
Vol 7 (4) ◽  
pp. 1355-1373 ◽  
Author(s):  
Ulrike Steiner ◽  
Sabine Hellwig ◽  
Mahalia Ahimsa-Müller ◽  
Nicola Grundmann ◽  
Shu-Ming Li ◽  
...  
Keyword(s):  
Host Plants ◽  
Glandular Trichomes ◽  
Clavicipitaceous Fungi

Ergot alkaloid biosynthesis by isolates of Balansia epichloë and B. henningsiana

1981 ◽  
Vol 59 (12) ◽  
pp. 2534-2538 ◽  
Author(s):  
Charles W. Bacon ◽  
James K. Porter ◽  
Joe D. Robbins
Keyword(s):  
Ergot Alkaloid ◽  
Sampling Site ◽  
Total Yield ◽  
Ergot Alkaloids ◽  
Chemical Species ◽  
Alkaloid Biosynthesis ◽  
Andropogon Virginicus ◽  
Clavicipitaceous Fungi

Two endophytic clavicipitaceous fungi, Balansia epichloë and B. henningsiana, were isolated from several grasses, cultured on laboratory media, and assessed for their ability to produce the major ergot alkaloids agroclavine, chanoclavine (I), ergonovine, and ergonovinine. Data indicated that the ability of these two species of fungi to biosynthesize ergot alkaloids was host related. All isolates of B. epichloë from smut-grass (Sporobolus poiretii) and 59% of the isolates of B. henningsiana from broom-sedge (Andropogon virginicus) produced the major alkaloids in culture. All isolates of B. epichloë from Eragrostis secundiflora and E. hirsuta, and all isolates of B. henningsiana from Panicum tenerum failed to produce alkaloids. The total yield and chemical species of individual alkaloids varied among isolates from a sampling site.

Sign in / Sign up

Export Citation Format

Share Document