Understanding the Role of Surface Charges in Cellular Adsorption versus Internalization by Selectively Removing Gold Nanoparticles on the Cell Surface with a I2/KI Etchant

Nano Letters ◽  
2009 ◽  
Vol 9 (3) ◽  
pp. 1080-1084 ◽  
Author(s):  
Eun Chul Cho ◽  
Jingwei Xie ◽  
Patricia A. Wurm ◽  
Younan Xia
Keyword(s):  
Gold Nanoparticles ◽  
Cell Surface ◽  
Surface Charges

Interaction of polymer-coated gold nanoparticles with cellobiose dehydrogenase: The role of surface charges

2018 ◽  
Vol 819 ◽  
pp. 226-233 ◽  
Author(s):  
Mojtaba Tavahodi ◽  
Christopher Schulz ◽  
Anna Assarsson ◽  
Roberto Ortiz ◽  
Roland Ludwig ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Cellobiose Dehydrogenase ◽  
Surface Charges

The Role of the Interaction between Fe(III) and Cell Surface in the Accumulation of 67Ga by Tumor Cells

1991 ◽  
Vol 30 (06) ◽  
pp. 290-293 ◽  
Author(s):  
P. Maleki ◽  
A. Martinezi ◽  
M. C. Crone-Escanye ◽  
J. Robert ◽  
L. J. Anghileri
Keyword(s):  
Cell Surface ◽  
Tumor Cells ◽  
Ionic Composition ◽  
Iron Complex ◽  
Iron Binding ◽  
Complex Time ◽  
Interaction Product ◽  
Thermodynamic Constant ◽  
Number Of Cells

The study of the interaction between complexed iron and tumor cells in the presence of 67Ga-citrate indicates that a phenomenon of iron-binding related to the thermodynamic constant of stability of the iron complex, and a hydrolysis (or anion penetration) of the interaction product determine the uptake of 67Ga. The effects of various parameters such as ionic composition of the medium, nature of the iron complex, time of incubation and number of cells are discussed.

Gold nanoparticles decorated with oligo(ethylene glycol) thiols: Surface charges and interactions with proteins in solution

2014 ◽  
Vol 426 ◽  
pp. 31-38 ◽  
Author(s):  
Moritz Schollbach ◽  
Fajun Zhang ◽  
Felix Roosen-Runge ◽  
Maximilian W.A. Skoda ◽  
Robert M.J. Jacobs ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Ethylene Glycol ◽  
Surface Charges

scholarly journals Gold Nanoparticles Inhibit VEGF165-Induced Migration and Tube Formation of Endothelial Cells via the Akt Pathway

2014 ◽  
Vol 2014 ◽  
pp. 1-11 ◽  
Author(s):  
Yunlong Pan ◽  
Qing Wu ◽  
Li Qin ◽  
Jiye Cai ◽  
Bin Du
Keyword(s):  
Gold Nanoparticles ◽  
Cell Migration ◽  
Endothelial Cell ◽  
Cell Surface ◽  
Umbilical Vein ◽  
Critical Role ◽  
Chorioallantoic Membrane ◽  
Tube Formation ◽  
Endothelial Cell Proliferation ◽  
Akt Pathway

The early stages of angiogenesis can be divided into three steps: endothelial cell proliferation, migration, and tube formation. Vascular endothelial growth factor (VEGF) is considered the most important proangiogenic factor; in particular, VEGF165plays a critical role in angiogenesis. Here, we evaluated whether gold nanoparticles (AuNPs) could inhibit the VEGF165-induced human umbilical vein endothelial cell (HUVEC) migration and tube formation. AuNPs and VEGF165were coincubated overnight at 4°C, after which the effects on cell migration and tube formation were assessed. Cell migration was assessed using a modified wound-healing assay and a transwell chamber assay; tube formation was assessed using a capillary-like tube formation assay and a chick chorioallantoic membrane (CAM) assay. We additionally detected the cell surface morphology and ultrastructure using atomic force microscopy (AFM). Furthermore, Akt phosphorylation downstream of VEGFR-2/PI3K in HUVECs was determined in a Western blot analysis. Our study demonstrated that AuNPs significantly inhibited VEGF165-induced HUVEC migration and tube formation by affecting the cell surface ultrastructure, cytoskeleton and might have inhibited angiogenesis via the Akt pathway.

The Role of Silver and Gold Nanoparticles in Enhancing Luminescence of Europium Complexes

2014 ◽  
Vol 14 (6) ◽  
pp. 4357-4362 ◽  
Author(s):  
Hongyan Zhao ◽  
Feng Song ◽  
Fengxiao Wang ◽  
Jiadong Liu ◽  
Yanling Liu ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Europium Complexes ◽  
Silver And Gold Nanoparticles
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