Quantum Dot−Aptamer Conjugates for Synchronous Cancer Imaging, Therapy, and Sensing of Drug Delivery Based on Bi-Fluorescence Resonance Energy Transfer

Nano Letters ◽  
2007 ◽  
Vol 7 (10) ◽  
pp. 3065-3070 ◽  
Author(s):  
Vaishali Bagalkot ◽  
Liangfang Zhang ◽  
Etgar Levy-Nissenbaum ◽  
Sangyong Jon ◽  
Philip W. Kantoff ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Energy Transfer ◽  
Quantum Dot ◽  
Fluorescence Resonance Energy Transfer ◽  
Cancer Imaging ◽  
Resonance Energy Transfer ◽  
Resonance Energy ◽  
Synchronous Cancer ◽  
Fluorescence Resonance

Fluorescence resonance energy transfer monitoring of pH-responsive doxorubicin release from carbon dots/aptamer functionalized magnetic mesoporous silica

Nanomedicine ◽  
2021 ◽  
Author(s):  
Abolghasem Abbasi Kajani ◽  
Masoud Ayatollahi Mehrgardi
Keyword(s):  
Drug Delivery ◽  
Energy Transfer ◽  
Fluorescence Resonance Energy Transfer ◽  
Carbon Dots ◽  
Drug Loading ◽  
Resonance Energy Transfer ◽  
Resonance Energy ◽  
Spectroscopic Techniques ◽  
Ph Responsive ◽  
Fluorescence Resonance

Aim: To develop a novel theranostic nanoplatform for simultaneous fluorescent monitoring and stimuli-triggered drug delivery. Materials & methods: Different microscopic and spectroscopic techniques were used for the characterization of nanocarriers. MCF-7 and human umbilical vein endothelial cell lines were cultured and treated with different doses of doxorubicin-loaded nanocarriers. The cell viability and drug release were studied using MTT assay and fluorescence microscopy. Results: Biocompatible and mono-disperse nanocarriers represent hollow and mesoporous structures with the calculated surface area of 552.83 m2.g-1, high magnetic activity (12.6 emu.g-1), appropriate colloidal stability and high drug loading capacity (up to 61%). Conclusion: Taxane-based carbon dots act as the pH-responsive gatekeepers for the controlled release of doxorubicin into cancer cells and provide a fluorescence resonance energy transfer system for real-time monitoring of drug delivery.

Fluorescence resonance energy transfer-based drug delivery systems for enhanced photodynamic therapy

2020 ◽  
Vol 8 (17) ◽  
pp. 3772-3788 ◽  
Author(s):  
Yu Huang ◽  
Feng Qiu ◽  
Rongjun Chen ◽  
Deyue Yan ◽  
Xinyuan Zhu
Keyword(s):  
Drug Delivery ◽  
Photodynamic Therapy ◽  
Energy Transfer ◽  
Fluorescence Resonance Energy Transfer ◽  
Drug Delivery Systems ◽  
Resonance Energy Transfer ◽  
Resonance Energy ◽  
Delivery Systems ◽  
Recent Advances ◽  
Fluorescence Resonance

In this Review, recent advances in fluorescence resonance energy transfer-based drug delivery systems for enhanced photodynamic therapy are described, and the current challenges and perspectives in this emerging field are also discussed.

Fluorescence Resonance Energy Transfer Between Quantum Dot Donors and Dye-Labeled Protein Acceptors

2004 ◽  
Vol 126 (1) ◽  
pp. 301-310 ◽  
Author(s):  
Aaron R. Clapp ◽  
Igor L. Medintz ◽  
J. Matthew Mauro ◽  
Brent R. Fisher ◽  
Moungi G. Bawendi ◽  
...  
Keyword(s):  
Energy Transfer ◽  
Quantum Dot ◽  
Fluorescence Resonance Energy Transfer ◽  
Resonance Energy Transfer ◽  
Resonance Energy ◽  
Fluorescence Resonance
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