scholarly journals Inhibition of Hepatitis C Virus by the Cyanobacterial ProteinMicrocystis viridisLectin: Mechanistic Differences between the High-Mannose Specific Lectins MVL, CV-N, and GNA

2013 ◽  
Vol 10 (12) ◽  
pp. 4590-4602 ◽  
Author(s):  
Alla Kachko ◽  
Sandra Loesgen ◽  
Syed Shahzad-ul-Hussan ◽  
Wendy Tan ◽  
Iryna Zubkova ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
High Mannose

scholarly journals Effects of microvirin monomers and oligomers on hepatitis C virus

2017 ◽  
Vol 37 (3) ◽  
Author(s):  
Yuan-Qin Min ◽  
Xu-Chu Duan ◽  
Yi-Dan Zhou ◽  
Anna Kulinich ◽  
Wang Meng ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
High Specificity ◽  
Antiviral Effect ◽  
Carbohydrate Binding ◽  
Viral Inhibition ◽  
Linker Sequence ◽  
Carbohydrate Binding Protein ◽  
High Mannose ◽  
Tetrameric Form

Microvirin (MVN) is a carbohydrate-binding protein which shows high specificity for high-mannose type N-glycan structures. In the present study, we tried to identify whether MVN could bind to high-mannose containing hepatitis C virus (HCV) envelope glycoproteins, which are heavily decorated high-mannose glycans. In addition, recombinantly expressed MVN oligomers in di-, tri- and tetrameric form were evaluated for their viral inhibition. MVN oligomers bound more efficiently to HCV virions, and displayed in comparison with the MVN monomer a higher neutralization potency against HCV infection. The antiviral effect was furthermore affected by the peptide linker sequence connecting the MVN monomers. The results indicate that MVN oligomers such as trimers and tetramers may be used as future neutralization agents against HCV infections.

HEPATITIS C VIRUS INFECTION (AND ADDITIONAL NEOPLASMS) AMONG MARGINAL ZONE LYMPHOMAS

1997 ◽  
Vol 96 (2) ◽  
pp. 427-428 ◽  
Author(s):  
FREDERICO SILVESTRI ◽  
GIOVANNI BARILLARI ◽  
RENATO FANIN ◽  
FLAVIA SALMASO ◽  
LAURA INFANTI ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Virus Infection ◽  
Marginal Zone ◽  
Hepatitis C Virus Infection

Public health challenges in hepatitis C virus infection

2000 ◽  
Vol 15 (5 (Suppl.)) ◽  
pp. E83-E90 ◽  
Author(s):  
John M Kaldor ◽  
Gregory J Dore ◽  
Patricia Kl Correll
Keyword(s):  
Public Health ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Virus Infection ◽  
Hepatitis C Virus Infection ◽  
Public Health Challenges

Expression of CD81, am ligand for hepatitis C virus (HCV) is increased on CD5+ B-lymphocytes but may not be the receptor for internalisation of HCV

2001 ◽  
Vol 120 (5) ◽  
pp. A552-A552
Author(s):  
M CURRY ◽  
T DEIGNAN ◽  
P COSTELLO ◽  
L GOLDENMASON ◽  
M DUFFY ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
B Lymphocytes

Analysis of interferon signal expression in hepatitis C virus-infected patients' lymphocytes

2001 ◽  
Vol 120 (5) ◽  
pp. A570-A570
Author(s):  
T TANAKA ◽  
K ASAO ◽  
K INOUE ◽  
K KOHARATSUKIYAMA ◽  
M KOHARA
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C

Evolution of hepatitis C virus quasispecies after liver transplantation

2001 ◽  
Vol 120 (5) ◽  
pp. A373-A374
Author(s):  
A LYRA ◽  
X FAN ◽  
S RAMRAKHIANI ◽  
A DIBISCEGLIE
Keyword(s):  
Liver Transplantation ◽  
Hepatitis C Virus ◽  
Hepatitis C

Psychiatric and drug use disorders among veterans infected with hepatitis C virus

2001 ◽  
Vol 120 (5) ◽  
pp. A409-A409
Author(s):  
H ELSERAG ◽  
M KUNIK ◽  
P RICHARDSON ◽  
L RABENECK
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Drug Use ◽  
Drug Use Disorders
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