A Novel Sustained-Release Formulation of Recombinant Human Growth Hormone and Its Pharmacokinetic, Pharmacodynamic and Safety Profiles

Yi Wei; Yuxia Wang; Aijun Kang; Wei Wang; Sa V. Ho; Junfeng Gao; Guanghui Ma; Zhiguo Su

doi:10.1021/mp300126t

A Novel Sustained-Release Formulation of Recombinant Human Growth Hormone and Its Pharmacokinetic, Pharmacodynamic and Safety Profiles

Molecular Pharmaceutics ◽

10.1021/mp300126t ◽

2012 ◽

Vol 9 (7) ◽

pp. 2039-2048 ◽

Cited By ~ 27

Author(s):

Yi Wei ◽

Yuxia Wang ◽

Aijun Kang ◽

Wei Wang ◽

Sa V. Ho ◽

...

Keyword(s):

Growth Hormone ◽

Sustained Release ◽

Human Growth Hormone ◽

Recombinant Human Growth Hormone ◽

Human Growth ◽

Release Formulation ◽

Sustained Release Formulation

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Development of a novel sustained release formulation of recombinant human growth hormone using sodium hyaluronate microparticles

Journal of Controlled Release ◽

10.1016/j.jconrel.2005.02.012 ◽

2005 ◽

Vol 104 (2) ◽

pp. 323-335 ◽

Cited By ~ 100

Author(s):

Sun Jin Kim ◽

Sei Kwang Hahn ◽

Myung Jin Kim ◽

Duk Hee Kim ◽

Young Phil Lee

Keyword(s):

Growth Hormone ◽

Sustained Release ◽

Human Growth Hormone ◽

Recombinant Human Growth Hormone ◽

Sodium Hyaluronate ◽

Human Growth ◽

Release Formulation ◽

Sustained Release Formulation

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Development and Characterization of Sodium Hyaluronate Microparticle-Based Sustained Release Formulation of Recombinant Human Growth Hormone Prepared by Spray-Drying

Journal of Pharmaceutical Sciences ◽

10.1016/j.xphs.2015.11.046 ◽

2016 ◽

Vol 105 (2) ◽

pp. 613-622 ◽

Cited By ~ 5

Author(s):

Sun J. Kim ◽

Chan W. Kim

Keyword(s):

Growth Hormone ◽

Sustained Release ◽

Spray Drying ◽

Human Growth Hormone ◽

Recombinant Human Growth Hormone ◽

Sodium Hyaluronate ◽

Human Growth ◽

Release Formulation ◽

Sustained Release Formulation

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Characterization of recombinant human growth hormone variants from sodium hyaluronate-based sustained release formulation of rhGH under heat stress

Analytical Biochemistry ◽

10.1016/j.ab.2015.04.028 ◽

2015 ◽

Vol 485 ◽

pp. 59-65 ◽

Cited By ~ 1

Author(s):

Sun Jin Kim ◽

Chan Wha Kim

Keyword(s):

Growth Hormone ◽

Heat Stress ◽

Sustained Release ◽

Human Growth Hormone ◽

Recombinant Human Growth Hormone ◽

Sodium Hyaluronate ◽

Human Growth ◽

Release Formulation ◽

Sustained Release Formulation

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Characterization and In Vivo Study of Sustained-Release Formulation of Human Growth Hormone Using Sodium Hyaluronate

Pharmaceutical Research ◽

10.1023/b:pham.0000036910.41224.de ◽

2004 ◽

Vol 21 (8) ◽

pp. 1374-1381 ◽

Cited By ~ 41

Author(s):

Sei Kwang Hahn ◽

Sun Jin Kim ◽

Myung Jin Kim ◽

Duk Hee Kim

Keyword(s):

Growth Hormone ◽

Sustained Release ◽

Human Growth Hormone ◽

Sodium Hyaluronate ◽

Human Growth ◽

In Vivo Study ◽

Release Formulation ◽

Sustained Release Formulation

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Development of Recombinant Human Growth Hormone (rhGH) sustained-release microspheres by a low temperature aqueous phase/aqueous phase emulsion method

European Journal of Pharmaceutical Sciences ◽

10.1016/j.ejps.2014.05.027 ◽

2014 ◽

Vol 62 ◽

pp. 141-147 ◽

Cited By ~ 15

Author(s):

Jian Kang ◽

Fei Wu ◽

Yunpeng Cai ◽

Mingxin Xu ◽

Mu He ◽

...

Keyword(s):

Growth Hormone ◽

Low Temperature ◽

Sustained Release ◽

Aqueous Phase ◽

Human Growth Hormone ◽

Recombinant Human Growth Hormone ◽

Human Growth ◽

Emulsion Method ◽

Sustained Release Microspheres

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Sustained-Release Recombinant Human Growth Hormone Improved Body Composition and Quality of Life in Adults over 50 Years Old with Somatopause

10.1210/endo-meetings.2011.part3.p1.p2-418 ◽

2011 ◽

pp. P2-418-P2-418

Author(s):

Hannah Seok ◽

Jae Won Hong ◽

Yoon Sok Chung ◽

Sung Woon Kim ◽

Eun Jig Lee ◽

...

Keyword(s):

Quality Of Life ◽

Growth Hormone ◽

Body Composition ◽

Sustained Release ◽

Human Growth Hormone ◽

Recombinant Human Growth Hormone ◽

Human Growth

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Development of a sustained-release recombinant human growth hormone formulation

Journal of Controlled Release ◽

10.1016/j.jconrel.2009.03.014 ◽

2009 ◽

Vol 137 (2) ◽

pp. 160-165 ◽

Cited By ~ 38

Author(s):

H.H. Kwak ◽

W.S. Shim ◽

M.K. Choi ◽

M.K. Son ◽

Y.J. Kim ◽

...

Keyword(s):

Growth Hormone ◽

Sustained Release ◽

Human Growth Hormone ◽

Recombinant Human Growth Hormone ◽

Human Growth

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Economic evaluation of a weekly administration of a sustained-release injection of recombinant human growth hormone for the treatment of children with growth hormone deficiency

Korean Journal of Pediatrics ◽

10.3345/kjp.2009.52.11.1249 ◽

2009 ◽

Vol 52 (11) ◽

pp. 1249

Author(s):

Hye-Young Kang ◽

Duk Hee Kim ◽

Sei-Won Yang ◽

Yoon-Nam Kim ◽

Miseon Kim

Keyword(s):

Growth Hormone ◽

Economic Evaluation ◽

Sustained Release ◽

Growth Hormone Deficiency ◽

Human Growth Hormone ◽

Recombinant Human Growth Hormone ◽

Human Growth ◽

Hormone Deficiency ◽

Weekly Administration

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SUSTAINED-RELEASE RECOMBINANT HUMAN GROWTH HORMONE IMPROVES BODY COMPOSITION AND QUALITY OF LIFE IN ADULTS WITH SOMATOPAUSE

Journal of the American Geriatrics Society ◽

10.1111/j.1532-5415.2011.03382.x ◽

2011 ◽

Vol 59 (5) ◽

pp. 944-947 ◽

Cited By ~ 6

Author(s):

Jeong Kyung Park ◽

Jae Won Hong ◽

Chang Oh Kim ◽

Sang Woo Kim ◽

Chi-Yeon Lim ◽

...

Keyword(s):

Quality Of Life ◽

Growth Hormone ◽

Body Composition ◽

Sustained Release ◽

Human Growth Hormone ◽

Recombinant Human Growth Hormone ◽

Human Growth

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Biodegradable laminar implants for sustained release of recombinant human growth hormone

Biomaterials ◽

10.1016/s0142-9612(02)00225-9 ◽

2002 ◽

Vol 23 (24) ◽

pp. 4759-4764 ◽

Cited By ~ 11

Author(s):

Juan T Garcı́a ◽

Mª Jesús Dorta ◽

Obdulia Munguı́a ◽

Matı́as Llabrés ◽

José B Fariña

Keyword(s):

Growth Hormone ◽

Sustained Release ◽

Human Growth Hormone ◽

Recombinant Human Growth Hormone ◽

Human Growth

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