Intravenous Delivery of Hydrophobin-Functionalized Porous Silicon Nanoparticles: Stability, Plasma Protein Adsorption and Biodistribution

2012 ◽  
Vol 9 (3) ◽  
pp. 654-663 ◽  
Author(s):  
Mirkka Sarparanta ◽  
Luis M. Bimbo ◽  
Jussi Rytkönen ◽  
Ermei Mäkilä ◽  
Timo J. Laaksonen ◽  
...  
Keyword(s):  
Porous Silicon ◽  
Protein Adsorption ◽  
Plasma Protein ◽  
Silicon Nanoparticles ◽  
Porous Silicon Nanoparticles ◽  
Nanoparticles Stability ◽  
Plasma Protein Adsorption

Fusogenic porous silicon nanoparticles as a broad-spectrum immunotherapy against bacterial infections

2021 ◽  
Author(s):  
Byungji Kim ◽  
Qinglin Yang ◽  
Leslie W. Chan ◽  
Sangeeta N. Bhatia ◽  
Erkki Ruoslahti ◽  
...  
Keyword(s):  
Porous Silicon ◽  
Broad Spectrum ◽  
Therapeutic Efficacy ◽  
Bacterial Infections ◽  
Silicon Nanoparticles ◽  
First Line ◽  
Gram Positive ◽  
Gram Negative ◽  
Porous Silicon Nanoparticles

RNAi-mediated immunotherapy provided by fusogenic porous silicon nanoparticles demonstrates superior therapeutic efficacy against both Gram-positive and Gram-negative bacterial infections compared with first-line antibiotics.

Plasma protein adsorption and biological identity of systemically administered nanoparticles

Nanomedicine ◽  
2017 ◽  
Vol 12 (17) ◽  
pp. 2113-2135 ◽  
Author(s):  
Dongyu Chen ◽  
Shanthi Ganesh ◽  
Weimin Wang ◽  
Mansoor Amiji
Keyword(s):  
Protein Adsorption ◽  
Plasma Protein ◽  
Plasma Protein Adsorption
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