Small Interfering RNA Knocks Down the Molecular Target of Alendronate, Farnesyl Pyrophosphate Synthase, in Osteoclast and Osteoblast Cultures

Yuwei Wang; Alexandra Panasiuk; David W. Grainger

doi:10.1021/mp100374n

Small Interfering RNA Knocks Down the Molecular Target of Alendronate, Farnesyl Pyrophosphate Synthase, in Osteoclast and Osteoblast Cultures

Molecular Pharmaceutics ◽

10.1021/mp100374n ◽

2011 ◽

Vol 8 (4) ◽

pp. 1016-1024 ◽

Cited By ~ 13

Author(s):

Yuwei Wang ◽

Alexandra Panasiuk ◽

David W. Grainger

Keyword(s):

Small Interfering Rna ◽

Molecular Target ◽

Farnesyl Pyrophosphate ◽

Farnesyl Pyrophosphate Synthase ◽

Interfering Rna

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Farnesyl Pyrophosphate Synthase Is the Molecular Target of Nitrogen-Containing Bisphosphonates

Biochemical and Biophysical Research Communications ◽

10.1006/bbrc.1999.1499 ◽

1999 ◽

Vol 264 (1) ◽

pp. 108-111 ◽

Cited By ~ 330

Author(s):

Ermond van Beek ◽

Elsbet Pieterman ◽

Louis Cohen ◽

Clemens Löwik ◽

Socrates Papapoulos

Keyword(s):

Molecular Target ◽

Farnesyl Pyrophosphate ◽

Farnesyl Pyrophosphate Synthase

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Farnesyl pyrophosphate synthase: a key enzyme in isoprenoid biosynthetic pathway and potential molecular target for drug development

New Biotechnology ◽

10.1016/j.nbt.2012.07.001 ◽

2013 ◽

Vol 30 (2) ◽

pp. 114-123 ◽

Cited By ~ 59

Author(s):

Manoj K. Dhar ◽

Archana Koul ◽

Sanjana Kaul

Keyword(s):

Drug Development ◽

Biosynthetic Pathway ◽

Molecular Target ◽

Farnesyl Pyrophosphate ◽

Farnesyl Pyrophosphate Synthase ◽

Key Enzyme ◽

Isoprenoid Biosynthetic Pathway

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Prion or virino or just a small interfering RNA?

PsycEXTRA Dataset ◽

10.1037/e516032012-143 ◽

2004 ◽

Author(s):

Y. E. Karapetyan

Keyword(s):

Small Interfering Rna ◽

Interfering Rna

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Cloning and characterization of Farnesyl pyrophosphate synthase gene from Anoectochilus

Pakistan Journal of Botany ◽

10.30848/pjb2020-3(14) ◽

2019 ◽

Vol 52 (3) ◽

Author(s):

Lin Yang ◽

Jun Cheng Zhang ◽

Wan Chen Li ◽

Jing Tao Qu ◽

Hao Qiang Yu ◽

...

Keyword(s):

Farnesyl Pyrophosphate ◽

Farnesyl Pyrophosphate Synthase

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Faculty Opinions recommendation of Adenovirus VA1 noncoding RNA can inhibit small interfering RNA and MicroRNA biogenesis.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1022420.255641 ◽

2004 ◽

Author(s):

Jim Smiley

Keyword(s):

Small Interfering Rna ◽

Noncoding Rna ◽

Microrna Biogenesis ◽

Interfering Rna

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Faculty Opinions recommendation of DICER-LIKE 4 is required for RNA interference and produces the 21-nucleotide small interfering RNA component of the plant cell-to-cell silencing signal.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1029052.345437 ◽

2005 ◽

Author(s):

Andy Maule

Keyword(s):

Rna Interference ◽

Plant Cell ◽

Small Interfering Rna ◽

Interfering Rna

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Faculty Opinions recommendation of Transvascular delivery of small interfering RNA to the central nervous system.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1087517.541813 ◽

2007 ◽

Author(s):

Günter Mayer

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Small Interfering Rna ◽

The Central Nervous System ◽

Interfering Rna

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Faculty Opinions recommendation of Transvascular delivery of small interfering RNA to the central nervous system.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1087517.541346 ◽

2007 ◽

Author(s):

Marina Picciotto

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Small Interfering Rna ◽

The Central Nervous System ◽

Interfering Rna

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Faculty Opinions recommendation of Targets of small interfering RNA restriction during human immunodeficiency virus type 1 replication.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1103370.559416 ◽

2008 ◽

Author(s):

Donald Burke

Keyword(s):

Human Immunodeficiency Virus ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Small Interfering Rna ◽

Immunodeficiency Virus ◽

Interfering Rna

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Faculty Opinions recommendation of Interleukin-6 small interfering RNA improved the herpes simplex virus-induced systemic inflammation in vivo Behcet's disease-like mouse model.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1158441.618600 ◽

2009 ◽

Author(s):

Florence Apparailly ◽

Gabriel Courties

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Mouse Model ◽

Systemic Inflammation ◽

Interleukin 6 ◽

Small Interfering Rna ◽

Behcet’S Disease ◽

Simplex Virus ◽

Interfering Rna

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