Synthesis of Organic and Water Soluble Poly(1,4-phenylenevinylenes) Containing Carboxyl Groups:  Living Ring-Opening Metathesis Polymerization (ROMP) of 2,3-Dicarboxybarrelenes

1997 ◽  
Vol 30 (14) ◽  
pp. 3978-3985 ◽  
Author(s):  
Michael W. Wagaman ◽  
Robert H. Grubbs
Keyword(s):  
Ring Opening ◽  
Water Soluble ◽  
Carboxyl Groups ◽  
Ring Opening Metathesis Polymerization ◽  
Metathesis Polymerization ◽  
Soluble Poly

scholarly journals Dewar Heterocycles as Versatile Monomers for Ring-Opening Metathesis Polymerization

2020 ◽  
Author(s):  
Sepand Nistanaki ◽  
Hosea Nelson
Keyword(s):  
Ring Opening ◽  
Water Soluble ◽  
Ring Opening Metathesis Polymerization ◽  
Valence Isomerization ◽  
Metathesis Polymerization ◽  
Grubbs Catalysts ◽  
Amino Acid Polymers ◽  
Highly Strained ◽  
Acetylene Derivatives ◽  
Soluble Poly

We report the utility of readily available heterocycles as precursors to unique ring-opening metathesis polymerization (ROMP) monomers. Photochemical valence isomerization reactions of pyridones, dihydropyridines, and pyrones dearomatize the parent heterocycles to their highly strained Dewar isomers, which readily engage in controlled ROMP reactions using Grubbs catalysts. This strategy is used to access novel polymer backbones that contain strained β-lactam and azetidine cores, which can be further derivatized using post-polymerization chemistries. We demonstrate this through the synthesis of water-soluble β-amino acid polymers and soluble poly(acetylene) derivatives.

scholarly journals Dewar Heterocycles as Versatile Monomers for Ring-Opening Metathesis Polymerization

2020 ◽  
Author(s):  
Sepand Nistanaki ◽  
Hosea Nelson
Keyword(s):  
Ring Opening ◽  
Water Soluble ◽  
Ring Opening Metathesis Polymerization ◽  
Valence Isomerization ◽  
Metathesis Polymerization ◽  
Grubbs Catalysts ◽  
Amino Acid Polymers ◽  
Highly Strained ◽  
Acetylene Derivatives ◽  
Soluble Poly

We report the utility of readily available heterocycles as precursors to unique ring-opening metathesis polymerization (ROMP) monomers. Photochemical valence isomerization reactions of pyridones, dihydropyridines, and pyrones dearomatize the parent heterocycles to their highly strained Dewar isomers, which readily engage in controlled ROMP reactions using Grubbs catalysts. This strategy is used to access novel polymer backbones that contain strained β-lactam and azetidine cores, which can be further derivatized using post-polymerization chemistries. We demonstrate this through the synthesis of water-soluble β-amino acid polymers and soluble poly(acetylene) derivatives.

Diblock brush-arm star copolymers via a core-first/graft-from approach using γ-cyclodextrin and ROMP: a modular platform for drug delivery

2020 ◽  
Vol 11 (2) ◽  
pp. 541-550 ◽  
Author(s):  
Ruihan Li ◽  
Xuesong Li ◽  
Yipei Zhang ◽  
Abigail O. Delawder ◽  
Nathan D. Colley ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Anticancer Drug ◽  
Ring Opening ◽  
Water Soluble ◽  
Ring Opening Metathesis Polymerization ◽  
Metathesis Polymerization ◽  
Anticancer Drug Delivery ◽  
Star Copolymers ◽  
Modular Platform

Water-soluble diblock brush-arm star copolymers using γ-CD-based core-first ring-opening metathesis polymerization, allowing for anticancer drug delivery via host–guest interaction.

Aggregation-induced emission block copolymers based on ring-opening metathesis polymerization

RSC Advances ◽  
2014 ◽  
Vol 4 (93) ◽  
pp. 51194-51200 ◽  
Author(s):  
Yuming Zhao ◽  
Ying Wu ◽  
Guowei Yan ◽  
Ke Zhang
Keyword(s):  
Block Copolymers ◽  
Self Assembly ◽  
Ring Opening ◽  
Water Soluble ◽  
Amphiphilic Block Copolymers ◽  
Ring Opening Metathesis Polymerization ◽  
Metathesis Polymerization ◽  
Aggregation Induced Emission ◽  
Selective Solvents ◽  
First Time

AIE amphiphilic block copolymers were developed from ROMP for the first time. By self-assembly in selective solvents, water soluble fluorescent nano-objects were prepared with varied structures including micelles and vesicles.

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