Self-Assembling Properties of Well-Defined Poly(ethylene oxide)-b-poly(ethyl acrylate) Diblock Copolymers

2009 ◽  
Vol 42 (12) ◽  
pp. 4262-4272 ◽  
Author(s):  
Sandie Piogé ◽  
Laurent Fontaine ◽  
Cédric Gaillard ◽  
Erwan Nicol ◽  
Sagrario Pascual
Keyword(s):  
Ethylene Oxide ◽  
Diblock Copolymers ◽  
Ethyl Acrylate ◽  
Self Assembling ◽  
Poly Ethylene Oxide ◽  
Poly Ethylene

Block Copolymer Nanosystems Encapsulating Magnetic Nanoparticles and Drug

2020 ◽  
Vol 20 (7) ◽  
pp. 3981-3988 ◽  
Author(s):  
E. Vlassi ◽  
A. Papagiannopoulos ◽  
A. Sergides ◽  
S. Pispas
Keyword(s):  
Magnetic Nanoparticles ◽  
Ethylene Oxide ◽  
Diblock Copolymers ◽  
Serum Proteins ◽  
Aqueous Media ◽  
Self Assembling ◽  
Bio Imaging ◽  
Poly Ethylene Oxide ◽  
Amphiphilic Diblock Copolymers ◽  
Poly Ethylene

The goal of this study was to investigate the solution behavior of nanosystems composed of self-assembling amphiphilic diblock copolymers, poly(ethylene oxide-b-phenyl oxazoline) and poly(isoprene-b-ethylene oxide) (PEO-b-PPhOx and PI-b-PEO), with encapsulated iron oxide nanoparticles (γ-Fe2O3). The hybrid nanosystems were tested in aqueous solution, under physiological conditions and in mixtures with serum proteins. Light scattering methods were used to probe changes in size and mass of the formed aggregates in different solution conditions and as a function of storage time. The developed stable hybrid systems with encapsulated magnetic nanoparticles were able to entrap the anti-inflammatory drug, indomethacin. This work demonstrates versatile nanosystems with metal oxide characteristics for bio-imaging and the potential for drug delivery in aqueous media.

Photoluminescent polymeric micelles from poly(ethylene oxide)-block-poly(((4-vinylphenyl)ethene-1,1,2-triyl)tribenzene) diblock copolymers

2018 ◽  
Vol 42 (9) ◽  
pp. 7283-7292 ◽  
Author(s):  
Muhammad Adeel ◽  
Sen Xu ◽  
Bingjie Zhao ◽  
Lei Li ◽  
Sixun Zheng
Keyword(s):  
Ethylene Oxide ◽  
Diblock Copolymers ◽  
Polymeric Micelles ◽  
Raft Polymerization ◽  
Aqueous Media ◽  
Self Assembling ◽  
Poly Ethylene Oxide ◽  
Poly Ethylene

We report the synthesis of poly(ethylene oxide)-block-poly(((4-vinylphenyl)ethene-1,1,2-triyl)tribenzene) diblock copolymers via RAFT polymerization. The diblock copolymers were capable of self-assembling into photoluminescent micelles in aqueous media.

Composition and properties of complexes between anionic liposomes and diblock copolymers with cationic and poly(ethylene oxide) blocks

2017 ◽  
Vol 66 (11) ◽  
pp. 1669-1674 ◽  
Author(s):  
Oleg V Ivashkov ◽  
Andrey V Sybachin ◽  
Anna A Efimova ◽  
Viktor N Orlov ◽  
Dmitry V Pergushov ◽  
...  
Keyword(s):  
Ethylene Oxide ◽  
Diblock Copolymers ◽  
Anionic Liposomes ◽  
Poly Ethylene Oxide ◽  
Poly Ethylene

Synthesis, characterization and association behavior of linear-dendritic amphiphilic diblock copolymers based on poly(ethylene oxide) and a dendron derived from 2,2′-bis(hydroxymethyl)propionic acid

2015 ◽  
Vol 6 (12) ◽  
pp. 2274-2282 ◽  
Author(s):  
Weiwei Zhang ◽  
Weiwei Jiang ◽  
Delong Zhang ◽  
Guangyue Bai ◽  
Pengxiao Lou ◽  
...  
Keyword(s):  
Block Copolymers ◽  
Ethylene Oxide ◽  
Propionic Acid ◽  
Diblock Copolymers ◽  
Association Behavior ◽  
Poly Ethylene Oxide ◽  
Amphiphilic Diblock Copolymers ◽  
Poly Ethylene

Two new amphiphilic linear-dendritic block copolymers have been synthesized and characterized. And their association behaviors have also been studied.

Nanostructures from photo-cross-linked amphiphilic poly(ethylene oxide)-b-alkyl diblock copolymers

Polymer ◽  
2005 ◽  
Vol 46 (7) ◽  
pp. 2020-2028 ◽  
Author(s):  
Erwan Nicol ◽  
Frédérick Niepceron ◽  
Chantal Bonnans-Plaisance ◽  
Dominique Durand
Keyword(s):  
Ethylene Oxide ◽  
Diblock Copolymers ◽  
Poly Ethylene Oxide ◽  
Poly Ethylene

scholarly journals Chaperone-Like Effect of Polyzwitterions on the Interaction of C1q with IgG

2009 ◽  
Vol 64 (1-2) ◽  
pp. 149-154 ◽  
Author(s):  
Ivo Ivanov ◽  
Ivanka Tsacheva ◽  
Vishnia Stoyanova ◽  
Miroslav Nikolov ◽  
Magdalena I. Tchorbadjieva ◽  
...  
Keyword(s):  
Critical Micelle Concentration ◽  
Ethylene Oxide ◽  
Specific Protein ◽  
Zwitterionic Surfactant ◽  
Zwitterionic Surfactants ◽  
Denatured Protein ◽  
Self Assembling ◽  
Protein Molecules ◽  
Poly Ethylene Oxide ◽  
Poly Ethylene

The amphiphilic polyzwitterion (PZ) poly(ethylene oxide-b-N,N-dimethyl(methacryloyloxyethyl) ammonium propanesulfonate), zwitterionic surfactant (ZS) n-dodecyl- N,N-dimethyl-3-ammonium-1-propanesulfonate, and zwitterionic monomer (ZM) N,Ndimethyl( methacryloyloxyethyl)ammonium propanesulfonate were analyzed for their suggested chaperone-like effect on the interaction of C1q and IgG. Our results proved that the PZ retarded the C1q interaction with IgG, demonstrating a specific protein-folding helper effect. The ZS enhanced this interaction, when the ZS concentration was lower than the critical micelle concentration (CMC), and retarded it, when the ZS concentration was above the CMC. The ZM, with no self-assembling ability, did not influence this interaction. These results support the hypothesis of a hydrophobic interaction between Pts and hydrophobic domains of partly denatured protein molecules. The amphiphilic self-assemblies, formed by polyzwitterionic macromolecules or zwitterionic surfactants, have the ability to transform the hydrophobic domains of the protein molecules into hydrophilic ones, covering them with their hydrophilic parts.

Solution Crystallization Behavior of Crystalline−Crystalline Diblock Copolymers of Poly(ethylene oxide)-block-poly(ε-caprolactone)

2010 ◽  
Vol 43 (14) ◽  
pp. 6113-6119 ◽  
Author(s):  
Ryan M. Van Horn ◽  
Joseph X. Zheng ◽  
Hao-Jan Sun ◽  
Ming-Siao Hsiao ◽  
Wen-Bin Zhang ◽  
...  
Keyword(s):  
Ethylene Oxide ◽  
Crystallization Behavior ◽  
Diblock Copolymers ◽  
Solution Crystallization ◽  
Poly Ethylene Oxide ◽  
Poly Ethylene

scholarly journals Large and Giant Unilamellar Vesicle(s) Obtained by Self-Assembly of Poly(dimethylsiloxane)-b-poly(ethylene oxide) Diblock Copolymers, Membrane Properties and Preliminary Investigation of Their Ability to Form Hybrid Polymer/Lipid Vesicles

Polymers ◽  
2019 ◽  
Vol 11 (12) ◽  
pp. 2013 ◽  
Author(s):  
Martin Fauquignon ◽  
Emmanuel Ibarboure ◽  
Stéphane Carlotti ◽  
Annie Brûlet ◽  
Marc Schmutz ◽  
...  
Keyword(s):  
Light Scattering ◽  
Ethylene Oxide ◽  
Self Assembly ◽  
Diblock Copolymers ◽  
Lipid Vesicles ◽  
Membrane Properties ◽  
Membrane Thickness ◽  
Hybrid Polymer ◽  
Poly Ethylene Oxide ◽  
Poly Ethylene

In the emerging field of hybrid polymer/lipid vesicles, relatively few copolymers have been evaluated regarding their ability to form these structures and the resulting membrane properties have been scarcely studied. Here, we present the synthesis and self-assembly in solution of poly(dimethylsiloxane)-block-poly(ethylene oxide) diblock copolymers (PDMS-b-PEO). A library of different PDMS-b-PEO diblock copolymers was synthesized using ring-opening polymerization of hexamethylcyclotrisiloxane (D3) and further coupling with PEO chains via click chemistry. Self-assembly of the copolymers in water was studied using Dynamic Light Scattering (DLS), Static Light Scattering (SLS), Small Angle Neutron Scattering (SANS), and Cryo-Transmission Electron Microscopy (Cryo-TEM). Giant polymersomes obtained by electroformation present high toughness compared to those obtained from triblock copolymer in previous studies, for similar membrane thickness. Interestingly, these copolymers can be associated to phospholipids to form Giant Hybrid Unilamellar Vesicles (GHUV); preliminary investigations of their mechanical properties show that tough hybrid vesicles can be obtained.

Sign in / Sign up

Export Citation Format

Share Document