“Functional Poly(ethylene glycol)”: PEG-Based Random Copolymers with 1,2-Diol Side Chains and Terminal Amino Functionality

2010 ◽  
Vol 43 (20) ◽  
pp. 8511-8518 ◽  
Author(s):  
Christine Mangold ◽  
Frederik Wurm ◽  
Boris Obermeier ◽  
Holger Frey
Keyword(s):  
Ethylene Glycol ◽  
Random Copolymers ◽  
Side Chains ◽  
Poly Ethylene Glycol ◽  
Terminal Amino ◽  
Poly Ethylene

Properties of Waterborne Polyurethane Having Poly(ethylene glycol) Side Chains for Waterproof Breathable Coating

Polymer Korea ◽  
2018 ◽  
Vol 42 (3) ◽  
pp. 417-426
Author(s):  
Baek Beom Seo ◽  
Young Chul Han ◽  
Jeong Han Yang ◽  
Jae Woo Jeon ◽  
Han Mo Jeong
Keyword(s):  
Ethylene Glycol ◽  
Waterborne Polyurethane ◽  
Side Chains ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

Swelling behaviour of hydrogels from methacrylic acid and poly(ethylene glycol) side chains by magnetic resonance imaging

2007 ◽  
Vol 56 (4) ◽  
pp. 506-511 ◽  
Author(s):  
Alberto Prior-Cabanillas ◽  
José M Barrales-Rienda ◽  
Gloria Frutos ◽  
Isabel Quijada-Garrido
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Ethylene Glycol ◽  
Methacrylic Acid ◽  
Side Chains ◽  
Resonance Imaging ◽  
Poly Ethylene Glycol ◽  
Swelling Behaviour ◽  
Poly Ethylene

scholarly journals Haemolytic activity of stonustoxin from stonefish (Synanceja horrida) venom: pore formation and the role of cationic amino acid residues

1997 ◽  
Vol 325 (3) ◽  
pp. 685-691 ◽  
Author(s):  
Desong CHEN ◽  
R. Manjunatha KINI ◽  
Raymond YUEN ◽  
Hoon Eng KHOO
Keyword(s):  
Cell Membrane ◽  
Ethylene Glycol ◽  
Haemolytic Activity ◽  
Side Chains ◽  
Poly Ethylene Glycol ◽  
Arginine Residues ◽  
Poly Ethylene ◽  
Cationic Residues ◽  
Positively Charged

Stonustoxin (SNTX) is a two-subunit protein toxin purified from the venom of the stonefish (Synanceja horrida), which induces potent haemolytic activity. We examined the pore-forming property of this non-enzymic protein by an osmotic protection assay. SNTX-induced haemolysis was completely prevented by osmotic protectants of adequate size [poly(ethylene) glycol 3000; molecular diameter approx. 3.2 nm]. Uncharged molecules of smaller size, such as raffinose and poly(ethylene) glycol 1000–2000, failed to protect against cell lysis. These findings indicate that SNTX induces the formation of hydrophilic pores in the cell membrane, which results in the lysis of erythrocytes. Since cationic residues contribute significantly to the cytolytic activity of several other pore-forming toxins, we examined the role of positively charged lysine and arginine residues in the haemolytic activity of SNTX. SNTX lost its haemolytic activity when the positively charged side chains of lysine residues were neutralized or converted into negatively charged side chains upon carbamylation or succinylation respectively. The haemolytic activity of SNTX was also inhibited by the modification of positively charged arginine residues using 2,3-butanedione. The loss of haemolysis showed strong correlation with the number of Lys or Arg residues modified. CD analyses, however, showed that the conformation of SNTX was not significantly affected by these chemical modifications. Further, the haemolytic activity of SNTX was competitively inhibited by various negatively charged lipids, such as phosphatidylserine, cardiolipin and monosialogangliosides. These results indicate that SNTX induces potent haemolytic activity through the formation of pores in the cell membrane, and that cationic residues play a crucial role in its cytolytic mechanism.

Nonhemolytic and Antibacterial Acrylic Copolymers with Hexamethyleneamine and Poly(ethylene glycol) Side Chains

2015 ◽  
Vol 4 (4) ◽  
pp. 426-430 ◽  
Author(s):  
Ashish Punia ◽  
Andrew Mancuso ◽  
Probal Banerjee ◽  
Nan-Loh Yang
Keyword(s):  
Ethylene Glycol ◽  
Side Chains ◽  
Poly Ethylene Glycol ◽  
Acrylic Copolymers ◽  
Poly Ethylene

scholarly journals Well-Defined Poly(lactic acid)s Containing Poly(ethylene glycol) Side Chains

2011 ◽  
Vol 45 (1) ◽  
pp. 62-69 ◽  
Author(s):  
José A. Castillo ◽  
Dorothee E. Borchmann ◽  
Amy Y. Cheng ◽  
Yufeng Wang ◽  
Chunhua Hu ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Ethylene Glycol ◽  
Poly Lactic Acid ◽  
Side Chains ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

Construction of semi-fluorinated amphiphilic graft copolymer bearing a poly(2-methyl-1,4-bistrifluorovinyloxybenzene) backbone and poly(ethylene glycol) side chains via the grafting-onto strategy

RSC Advances ◽  
2015 ◽  
Vol 5 (50) ◽  
pp. 39668-39676 ◽  
Author(s):  
Guolin Lu ◽  
Hao Liu ◽  
Haifeng Gao ◽  
Chun Feng ◽  
Yongjun Li ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Graft Copolymer ◽  
Graft Copolymers ◽  
Side Chains ◽  
Poly Ethylene Glycol ◽  
Amphiphilic Graft Copolymer ◽  
Amphiphilic Graft Copolymers ◽  
Poly Ethylene ◽  
Williamson Reaction ◽  
Grafting Onto

Amphiphilic graft copolymers bearing a hydrophobic PMBTFVB backbone and hydrophilic PEG side chains were synthesized by Williamson reaction through the grafting-onto strategy.

Synthesis of polycarbonate urethanes with functional poly(ethylene glycol) side chains intended for bioconjugates

Polymer ◽  
2013 ◽  
Vol 54 (20) ◽  
pp. 5363-5373 ◽  
Author(s):  
Yashuo Xu ◽  
Xiangyang Wu ◽  
Xingyi Xie ◽  
Yinping Zhong ◽  
Robert Guidoin ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Side Chains ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene
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