Characterization of Low-Mass Model 3-Arm Stars Produced in Reversible Addition−Fragmentation Chain Transfer (RAFT) Process

2004 ◽  
Vol 37 (12) ◽  
pp. 4434-4440 ◽  
Author(s):  
Yungwan Kwak ◽  
Atsushi Goto ◽  
Koichi Komatsu ◽  
Yukio Sugiura ◽  
Takeshi Fukuda
Keyword(s):  
Chain Transfer ◽  
Mass Model ◽  
Reversible Addition ◽  
Low Mass

scholarly journals Nano-Assemblies from Amphiphilic PnBA-b-POEGA Copolymers as Drug Nanocarriers

Polymers ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 1164
Author(s):  
Angeliki Chroni ◽  
Thomas Mavromoustakos ◽  
Stergios Pispas
Keyword(s):  
Molecular Weight ◽  
Chain Transfer ◽  
Raft Polymerization ◽  
Polymeric Nanocarriers ◽  
Reversible Addition ◽  
2D Noesy ◽  
Drug Nanocarriers ◽  
Glycol Methyl Ether ◽  
Different Molecular Weight

The focus of this study is the development of highly stable losartan potassium (LSR) polymeric nanocarriers. Two novel amphiphilic poly(n-butyl acrylate)-block-poly(oligo(ethylene glycol) methyl ether acrylate) (PnBA-b-POEGA) copolymers with different molecular weight (Mw) of PnBA are synthesized via reversible addition fragmentation chain transfer (RAFT) polymerization, followed by the encapsulation of LSR into both PnBA-b-POEGA micelles. Based on dynamic light scattering (DLS), the PnBA30-b-POEGA70 and PnBA27-b-POEGA73 (where the subscripts denote wt.% composition of the components) copolymers formed micelles of 10 nm and 24 nm in water. The LSR-loaded PnBA-b-POEGA nanocarriers presented increased size and greater mass nanostructures compared to empty micelles, implying the successful loading of LSR into the inner hydrophobic domains. A thorough NMR (nuclear magnetic resonance) characterization of the LSR-loaded PnBA-b-POEGA nanocarriers was conducted. Strong intermolecular interactions between the biphenyl ring and the butyl chain of LSR with the methylene signals of PnBA were evidenced by 2D-NOESY experiments. The highest hydrophobicity of the PnBA27-b-POEGA73 micelles contributed to an efficient encapsulation of LSR into the micelles exhibiting a greater value of %EE compared to PnBA30-b-POEGA70 + 50% LSR nanocarriers. Ultrasound release profiles of LSR signified that a great amount of the encapsulated LSR is strongly attached to both PnBA30-b-POEGA70 and PnBA27-b-POEGA73 micelles.

Light-responsive terpolymers based on polymerizable photoacids

2017 ◽  
Vol 8 (19) ◽  
pp. 2959-2971 ◽  
Author(s):  
Felix Wendler ◽  
Kilian R. A. Schneider ◽  
Benjamin Dietzek ◽  
Felix H. Schacher
Keyword(s):  
Radical Polymerization ◽  
Chain Transfer ◽  
Synthesis And Characterization ◽  
Reversible Addition

We present the synthesis and characterization of amphiphilic terpolymers containing photoacids based on 1-naphthol using reversible addition fragmentation chain transfer radical polymerization (RAFT).

Synthesis of Novel Triazole-Containing Phosphonate Polymers

2015 ◽  
Vol 68 (4) ◽  
pp. 680 ◽  
Author(s):  
Ciarán Dolan ◽  
Briar Naysmith ◽  
Simon F. R. Hinkley ◽  
Ian M. Sims ◽  
Margaret A. Brimble ◽  
...  
Keyword(s):  
Chain Transfer ◽  
Click Reaction ◽  
Raft Polymerization ◽  
Ethyl Acrylate ◽  
Polymer Chemistry ◽  
Synthesis And Characterization ◽  
Reversible Addition

The objective of this research was to develop novel phosphonate-containing polymers as they remain a relatively under researched area of polymer chemistry. Herein, we report the synthesis and characterization of 2-(1-(2-(diethoxyphosphoryl)ethyl)-1H-1,2,3-triazol-4-yl)ethyl acrylate (M1) and diethyl (2-(4-(2-acrylamidoethyl)-1H-1,2,3-triazol-1-yl)ethyl)phosphonate (M2) monomers using the copper-catalyzed azide–alkyne cycloaddition (CuAAC) ‘click’ reaction, and their subsequent polymerization via both uncontrolled and reversible addition–fragmentation chain transfer (RAFT) polymerization techniques yielding phosphonate polymers (P1–P4).

Chiral Recognition of L-Carnitine Using Surface Molecularly Imprinted Microspheres via RAFT Polymerization

2014 ◽  
Vol 884-885 ◽  
pp. 33-36 ◽  
Author(s):  
Lin Tong Hou ◽  
Jiao Jiao Chen ◽  
Hong Jun Fu ◽  
Xin Lei Fu
Keyword(s):  
Experimental Data ◽  
Chiral Recognition ◽  
Chain Transfer ◽  
Raft Polymerization ◽  
Isothermal Adsorption ◽  
Molecularly Imprinted ◽  
Reversible Addition ◽  
Ft Ir ◽  
Molecularly Imprinted Microspheres

A molecularly imprinted microsphere (MIPs) was prepared successfullyviasurface-initiated reversible addition-fragmentation chain transfer (RAFT) polymerization. Characterization of the obtained MIPs was achieved by FT-IR and TGA. The isothermal adsorption and chiral separation experiments of MIPs on L-Carnitine were investigated. Compared with non-imprinted microsphere (NMIPs) adsorbent, MIPs showed faster adsorption rate and stronger adsorption capacity for L-Carnitine. Equilibrium experimental data of MIPs fitted the Langmuir isotherm better. Furthermore, the MIPs also exhibited enantioselectivity for L-Carnitine through the resolution experiment.

Synthesis and characterization of bead-like poly(N-isopropylacrylamide) copolymers with double decker silsesquioxane in the main chains

2015 ◽  
Vol 6 (2) ◽  
pp. 256-269 ◽  
Author(s):  
Kun Wei ◽  
Lei Wang ◽  
Lei Li ◽  
Sixun Zheng
Keyword(s):  
Chain Transfer ◽  
Main Chain ◽  
Synthesis And Characterization ◽  
Double Decker ◽  
Reversible Addition ◽  
Chain Transfer Polymerization

A bead-like PNIPAAm copolymer with double-decker silsesquioxane (DDSQ) in the main chain was synthesized via a reversible addition–fragmentation chain transfer polymerization (RAFT) approach.

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