Kinetics of the conformational transition of poly(methacrylic acid) after changes of its degree of ionization

1985 ◽  
Vol 18 (10) ◽  
pp. 1940-1944 ◽  
Author(s):  
Bohumil Bednar ◽  
Herbert Morawetz ◽  
Jules A. Shafer
Keyword(s):  
Methacrylic Acid ◽  
Conformational Transition ◽  
Degree Of Ionization ◽  
Kinetics Of

Propagation Kinetics of Free-Radical Methacrylic Acid Polymerization in Aqueous Solution. The Effect of Concentration and Degree of Ionization

2007 ◽  
Vol 248 (1) ◽  
pp. 23-32 ◽  
Author(s):  
Sabine Beuermann ◽  
Michael Buback ◽  
Pascal Hesse ◽  
Silvia Kukučková ◽  
Igor Lacık
Keyword(s):  
Aqueous Solution ◽  
Free Radical ◽  
Methacrylic Acid ◽  
Degree Of Ionization ◽  
Kinetics Of

scholarly journals Membrane-tethered mucin-like polypeptides sterically inhibit binding and slow fusion kinetics of influenza A virus

2020 ◽  
Vol 117 (23) ◽  
pp. 12643-12650 ◽  
Author(s):  
Corleone S. Delaveris ◽  
Elizabeth R. Webster ◽  
Steven M. Banik ◽  
Steven G. Boxer ◽  
Carolyn R. Bertozzi
Keyword(s):  
Lipid Bilayers ◽  
Influenza A ◽  
Conformational Transition ◽  
Molecular Model ◽  
High Surface ◽  
Protective Mechanism ◽  
Dependent Manner ◽  
Influenza A Viruses ◽  
Virus Binding ◽  
Kinetics Of

The mechanism(s) by which cell-tethered mucins modulate infection by influenza A viruses (IAVs) remain an open question. Mucins form both a protective barrier that can block virus binding and recruit IAVs to bind cells via the sialic acids of cell-tethered mucins. To elucidate the molecular role of mucins in flu pathogenesis, we constructed a synthetic glycocalyx to investigate membrane-tethered mucins in the context of IAV binding and fusion. We designed and synthesized lipid-tethered glycopolypeptide mimics of mucins and added them to lipid bilayers, allowing chemical control of length, glycosylation, and surface density of a model glycocalyx. We observed that the mucin mimics undergo a conformational change at high surface densities from a compact to an extended architecture. At high surface densities, asialo mucin mimics inhibited IAV binding to underlying glycolipid receptors, and this density correlated to the mucin mimic’s conformational transition. Using a single virus fusion assay, we observed that while fusion of virions bound to vesicles coated with sialylated mucin mimics was possible, the kinetics of fusion was slowed in a mucin density-dependent manner. These data provide a molecular model for a protective mechanism by mucins in IAV infection, and therefore this synthetic glycocalyx provides a useful reductionist model for studying the complex interface of host–pathogen interactions.

Study of kinetics of vulcanization and structure of heterogeneous rubber with acrylic and methacrylic acid amides

1974 ◽  
Vol 16 (1) ◽  
pp. 256-264 ◽  
Author(s):  
A.A. Dontsov ◽  
A.A. Kanauzova ◽  
G.M. Sas'kova ◽  
B.A. Dogadkin
Keyword(s):  
Methacrylic Acid ◽  
Kinetics Of ◽  
Kinetics Of Vulcanization

Study of the kinetics of polymerization and copolymerization of methacrylic acid sulpholanate

1974 ◽  
Vol 16 (2) ◽  
pp. 405-411
Author(s):  
A.I. Vorob'eva ◽  
E.I. Ablyakimov ◽  
G.V. Leplyanin ◽  
S.R. Rafikov ◽  
G.P. Gladyshev
Keyword(s):  
Methacrylic Acid ◽  
Kinetics Of Polymerization ◽  
Kinetics Of
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