Diffusion-limited polymer-small molecule interactions: a study by phosphorescence quenching

1992 ◽  
Vol 25 (16) ◽  
pp. 4160-4166 ◽  
Author(s):  
Mark S. Gebert ◽  
Daniel H. S. Yu ◽  
John M. Torkelson
Keyword(s):  
Small Molecule ◽  
Phosphorescence Quenching ◽  
Diffusion Limited ◽  
Molecule Interactions

Small Molecule Interactions with Protein−Tyrosine Phosphatase PTP1B and Their Use in Inhibitor Design†

Biochemistry ◽  
1996 ◽  
Vol 35 (50) ◽  
pp. 15989-15996 ◽  
Author(s):  
Terrence R. Burke, ◽  
Bin Ye ◽  
Xinjian Yan ◽  
Shaomeng Wang ◽  
Zongchao Jia ◽  
...  
Keyword(s):  
Small Molecule ◽  
Protein Tyrosine Phosphatase ◽  
Tyrosine Phosphatase ◽  
Inhibitor Design ◽  
Protein Tyrosine ◽  
Molecule Interactions

Aggregation Characteristics of Cu and Ag Nanoparticles in Presence of Starch as the Polymer Stabilizer

2010 ◽  
Vol 123-125 ◽  
pp. 615-618 ◽  
Author(s):  
Indrajit Sinha ◽  
Manjeet Singh ◽  
Rajiv Kumar Mandal
Keyword(s):  
Small Molecule ◽  
Ag Nanoparticles ◽  
Growth Models ◽  
Chemical Reduction ◽  
Cluster Aggregation ◽  
Diffusion Limited ◽  
X Ray Scattering ◽  
Polymer Stabilizer ◽  
Aqueous Conditions ◽  
Diffusion Limited Cluster Aggregation

This presentation deals with the aggregation characteristics of Cu and Ag nanoparticles in presence of starch as the polymer stabilizer. Uncontrolled aggregation of the destabilized nanoparticles offers problem for applications based on surface plasmon activity. Polymer or small molecule surfactants are used to control nature of aggregation of nanoparticles produced by chemical reduction synthesis routes. Different growth models such as diffusion limited cluster aggregation (DLCA), reaction limited cluster aggregation (RLCA) proposed to explain the formation of fractal colloidal aggregates do not account for aggregate formation in presence of polymer or small molecule surfactants. We shall be discussing the role of starch on the aggregation characteristics of copper and silver nanoparticles formed by chemical reduction in aqueous conditions. The effect of NaOH concentration and consequently the pH on such aggregation kinetics during such synthesis is delineated. We use small angle x-ray scattering (SAXS) to quantitatively understand different aspects of aggregation behavior.

scholarly journals Identification of a Hydrophobic Cleft in the LytTR Domain of AgrA as a Locus for Small Molecule Interactions That Inhibit DNA Binding

Biochemistry ◽  
2012 ◽  
Vol 51 (50) ◽  
pp. 10035-10043 ◽  
Author(s):  
Paul G. Leonard ◽  
Ian F. Bezar ◽  
David J. Sidote ◽  
Ann M. Stock
Keyword(s):  
Dna Binding ◽  
Small Molecule ◽  
Molecule Interactions ◽  
Hydrophobic Cleft
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