Interactions between Poly(ethylene oxide) Layers Adsorbed to Glass Surfaces Probed by Using a Modified Atomic Force Microscope

Langmuir ◽  
1996 ◽  
Vol 12 (17) ◽  
pp. 4224-4237 ◽  
Author(s):  
G. J. C. Braithwaite ◽  
A. Howe ◽  
P. F. Luckham
Keyword(s):  
Ethylene Oxide ◽  
Atomic Force Microscope ◽  
Oxide Layers ◽  
Atomic Force ◽  
Poly Ethylene Oxide ◽  
Poly Ethylene ◽  
Glass Surfaces

scholarly journals Nonfouling Poly(ethylene oxide) Layers End-Tethered to Polydopamine

Langmuir ◽  
2012 ◽  
Vol 28 (40) ◽  
pp. 14273-14283 ◽  
Author(s):  
Ognen Pop-Georgievski ◽  
Dominique Verreault ◽  
Mark-Oliver Diesner ◽  
Vladimír Proks ◽  
Stefan Heissler ◽  
...  
Keyword(s):  
Ethylene Oxide ◽  
Oxide Layers ◽  
Poly Ethylene Oxide ◽  
Poly Ethylene

scholarly journals Enhancement in the antibacterial activity of cephalexin by its delivery through star-shaped poly(ε-caprolactone)-block-poly(ethylene oxide) coated silver nanoparticles

2020 ◽  
Vol 7 (10) ◽  
pp. 201097
Author(s):  
Sana Rahim ◽  
Samina Perveen ◽  
Shakil Ahmed ◽  
Muhammad Raza Shah ◽  
Muhammad Imran Malik
Keyword(s):  
Silver Nanoparticles ◽  
Antibacterial Activity ◽  
Ethylene Oxide ◽  
Inhibitory Concentration ◽  
Bacterial Cells ◽  
Force Microscopy ◽  
Atomic Force ◽  
Biofilm Destruction ◽  
Poly Ethylene Oxide ◽  
Poly Ethylene

The antibacterial activity of silver nanoparticles (AgNPs) stabilized with a four-armed star-shaped poly(ε-caprolactone)-block-poly(ethylene oxide) copolymer [St-P(CL-b-EO)] and its application as a drug delivery vehicle for cephalexin (Cp) was evaluated against pathogenic Staphylococcus aureus . The prepared AgNPs were characterized by ultraviolet-visible spectroscopy, Fourier transform infrared spectroscopy, zeta sizer and atomic force microscopy (AFM). The antibacterial efficiency of Cp is enhanced several-fold by its delivery through complexation with St-P(CL-b-EO)-AgNPs, monitored by microplate assay and biofilm destruction studies. Finally, the visual destruction of bacterial cells and its biofilms by employing Cp and its conjugates at their minimum inhibitory concentration (MIC 50 ) and minimum biofilm inhibitory concentration (MBIC 50 ), respectively, is observed by topographic imaging by AFM. Enhanced antibacterial activity of St-P(CL-b-EO)-AgNPs loaded Cp is attributed to penetrative nature of the drug cargo St-P(CL-b-EO)-AgNPs towards the bacterial cell wall.

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