Influence of Lipid-Bilayer-Associated Molecules on Lipid-Vesicle Adsorption

Langmuir ◽  
2010 ◽  
Vol 26 (8) ◽  
pp. 5706-5714 ◽  
Author(s):  
Kristian Dimitrievski
Keyword(s):  
Lipid Bilayer ◽  
Lipid Vesicle ◽  
Vesicle Adsorption

Simulations of Lipid Vesicle Adsorption for Different Lipid Mixtures

Langmuir ◽  
2008 ◽  
Vol 24 (8) ◽  
pp. 4077-4091 ◽  
Author(s):  
Kristian Dimitrievski ◽  
Bengt Kasemo
Keyword(s):  
Lipid Vesicle ◽  
Lipid Mixtures ◽  
Vesicle Adsorption

scholarly journals Interaction of botulinum and tetanus toxins with the lipid bilayer surface

1988 ◽  
Vol 251 (2) ◽  
pp. 379-383 ◽  
Author(s):  
C Montecucco ◽  
G Schiavo ◽  
Z Gao ◽  
E Bauerlein ◽  
P Boquet ◽  
...  
Keyword(s):  
Lipid Bilayer ◽  
Clostridium Botulinum ◽  
Membrane Surface ◽  
Light Chains ◽  
Lipid Vesicle ◽  
Clostridium Tetani ◽  
Tetanus Neurotoxin ◽  
Clostridial Neurotoxins ◽  
Zwitterionic Lipids ◽  
Botulinum Neurotoxins

The interaction of botulinum neurotoxins serotypes A, B and E (from Clostridium botulinum) and of tetanus neurotoxin (from Clostridium tetani) with the surface of liposomes made of different lipid compositions was studied by photolabelling with a radioiodinated photoactive phosphatidylethanolamine analogue [125I-dipalmitoyl (3,4-azidosalicylamido)phosphatidylethanolamine]. When the vesicles were made of negatively charged lipids (asolectin), each of these neurotoxic proteins was radioiodinated, thus providing evidence for their attachment to the membrane surface. The presence of gangliosides on liposome membranes enhanced fixation of the neurotoxic proteins to the lipid vesicle surface. Both the heavy and light chains of the clostridial neurotoxins were involved in the attachment to the lipid bilayer surface. Each of the toxins tested here attached poorly to liposomes made of zwitterionic lipids (egg phosphatidylcholine), even when polysialogangliosides were present. The data suggest that the binding of botulinum and tetanus neurotoxins to their target neuronal cells involves negatively charged lipids and polysialogangliosides on the cell membrane.

Spatiotemporal Kinetics of Supported Lipid Bilayer Formation on Glass via Vesicle Adsorption and Rupture

2018 ◽  
Vol 9 (17) ◽  
pp. 5143-5149 ◽  
Author(s):  
Mokhtar Mapar ◽  
Silver Jõemetsa ◽  
Hudson Pace ◽  
Vladimir P. Zhdanov ◽  
Björn Agnarsson ◽  
...  
Keyword(s):  
Lipid Bilayer ◽  
Supported Lipid Bilayer ◽  
Vesicle Adsorption ◽  
Kinetics Of ◽  
Bilayer Formation

Simulations of lipid vesicle rupture induced by an adjacent supported lipid bilayer patch

2011 ◽  
Vol 82 (2) ◽  
pp. 632-636 ◽  
Author(s):  
Oskar Allerbo ◽  
Anders Lundström ◽  
Kristian Dimitrievski
Keyword(s):  
Lipid Bilayer ◽  
Lipid Vesicle ◽  
Supported Lipid Bilayer ◽  
Vesicle Rupture

scholarly journals X-ray scattering from unilamellar lipid vesicles

2005 ◽  
Vol 38 (1) ◽  
pp. 126-131 ◽  
Author(s):  
Michael R. Brzustowicz ◽  
Axel T. Brunger
Keyword(s):  
Form Factor ◽  
Lipid Bilayer ◽  
Electron Density ◽  
Lipid Vesicles ◽  
Lipid Vesicle ◽  
Asymmetric Structure ◽  
Bilayer Structure ◽  
X Ray ◽  
X Ray Scattering ◽  
Ray Scattering

An improved small-angle X-ray scattering (SAXS) method for determining asymmetric lipid bilayer structure in unilamellar vesicles is presented. From scattering theory, analytic expressions are derived for the bilayer form factor over flat and spherical geometries, assuming the lipid bilayer electron density to be composed of a series of Gaussian shells. This is in contrast to both classic diffraction and Guinier hard-shell SAXS methods which, respectively, are capable only of ascertaining symmetric bilayer structure and limited-resolution asymmetric structure. Using model fitting and direct calculation of the form factor, using only one equation, an asymmetric electron density profile of the lipid vesicle is obtained with high accuracy, as well as the average radius. The analysis suggests that the inner leaflet of a unilamellar lipid vesicle is `rougher' than the outer one.

scholarly journals Nanoplasmonic ruler to measure lipid vesicle deformation

2016 ◽  
Vol 52 (1) ◽  
pp. 76-79 ◽  
Author(s):  
Joshua A. Jackman ◽  
Barbora Špačková ◽  
Eric Linardy ◽  
Min Chul Kim ◽  
Bo Kyeong Yoon ◽  
...  
Keyword(s):  
Direct Evidence ◽  
Lipid Vesicle ◽  
Membrane Tension ◽  
Vesicle Adsorption

A nanoplasmonic ruler measures vesicle deformation and provides direct evidence to support membrane tension-based models of vesicle adsorption and rupture.

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