Integral Geometry Analysis of Fluorescence Micrographs for Quantitative Relative Comparison of Protein Adsorption onto Polymer Surfaces

Langmuir ◽  
2008 ◽  
Vol 24 (18) ◽  
pp. 10253-10258 ◽  
Author(s):  
Joanna Zemła ◽  
Małgorzata Lekka ◽  
Joanna Wiltowska-Zuber ◽  
Andrzej Budkowski ◽  
Jakub Rysz ◽  
...  
Keyword(s):  
Protein Adsorption ◽  
Integral Geometry ◽  
Polymer Surfaces ◽  
Geometry Analysis

Self-Assembled Monolayers as Models for Studying Protein Adsorption to Polymer Surfaces

1991 ◽  
Vol 237 ◽  
Author(s):  
Kevin L. Prime ◽  
George M. Whttesides
Keyword(s):  
Ethylene Oxide ◽  
Protein Adsorption ◽  
Organic Materials ◽  
Polymer Surfaces ◽  
Self Assembled Monolayers ◽  
Assembled Monolayers ◽  
Poly Ethylene Oxide ◽  
Self Assembled ◽  
Protein Resistant ◽  
Poly Ethylene

ABSTRACTSelf-assembled monolayers (SAMs) of functionalized alkanethiolates on gold are a well-characterized system for studying the interfacial properties of organic materials. We have used SAMs as models for the surfaces of organic polymers and used mem to study the adsorption of proteins onto organic materials. We have formed SAMs from mixtures of alkanethiols in which one alkanethiol is hydrophobic and the other is terminated by a short (2 ≤ n ≤ 17) oligomer of poly(ethylene oxide). These “mixed” SAMs effectively resist the adsorption of fibrinogen from moderately concentrated (1 mg/mL) solutions. Protein adsorption begins when < 5% of the accessible area of the surface consists of hydrophobic groups. These findings suggest that real protein-resistant monolayers must present an almost defect-free surface of oligo(ethylene oxide) groups in order to eliminate adsorption.

Rapid Development of Hydrophilicity and Protein Adsorption Resistance by Polymer Surfaces Bearing Phosphorylcholine and Naphthalene Groups

Langmuir ◽  
2008 ◽  
Vol 24 (18) ◽  
pp. 10340-10344 ◽  
Author(s):  
Koji Futamura ◽  
Ryosuke Matsuno ◽  
Tomohiro Konno ◽  
Madoka Takai ◽  
Kazuhiko Ishihara
Keyword(s):  
Protein Adsorption ◽  
Rapid Development ◽  
Polymer Surfaces

Protein adsorption and platelet adhesion on polymer surfaces having phospholipid polar group connected with oxyethylene chain

1997 ◽  
Vol 8 (2) ◽  
pp. 91-102 ◽  
Author(s):  
Yasuhiko Iwasaki ◽  
Akiko Fujke ◽  
Kimio Kurita ◽  
Kazuhiko Ishihara ◽  
Nobuo Nakabayashi
Keyword(s):  
Protein Adsorption ◽  
Platelet Adhesion ◽  
Polymer Surfaces ◽  
Polar Group

Measurements of water sorption enthalpy on polymer surfaces and its effect on protein adsorption

2011 ◽  
Vol 605 (3-4) ◽  
pp. 419-423 ◽  
Author(s):  
Joonyeong Kim ◽  
Wei Qian ◽  
Zeki Y. Al-Saigh
Keyword(s):  
Protein Adsorption ◽  
Water Sorption ◽  
Polymer Surfaces ◽  
Sorption Enthalpy
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