Self-Assembling Peptide/Thermoresponsive Polymer Composite Hydrogels: Effect of Peptide–Polymer Interactions on Hydrogel Properties

Langmuir ◽  
2014 ◽  
Vol 30 (34) ◽  
pp. 10471-10480 ◽  
Author(s):  
A. Maslovskis ◽  
J.-B. Guilbaud ◽  
I. Grillo ◽  
N. Hodson ◽  
A. F. Miller ◽  
...  
2018 ◽  
Vol 6 (8) ◽  
pp. 2073-2083 ◽  
Author(s):  
Amir Sheikhi ◽  
Samson Afewerki ◽  
Rahmi Oklu ◽  
Akhilesh K. Gaharwar ◽  
Ali Khademhosseini

The effect of ionic strength on the structure and rheological properties of nanoclay–gelatin shear-thinning biomaterials (STBs) is investigated. A fundamental insight into nanoclay–polymer interactions in physiological environments is provided to design clay-based biomaterials for biomedical applications.


Langmuir ◽  
2014 ◽  
Vol 30 (46) ◽  
pp. 14056-14061 ◽  
Author(s):  
Beate Stempfle ◽  
Anna Große ◽  
Bernhard Ferse ◽  
Karl-Friedrich Arndt ◽  
Dominik Wöll

2012 ◽  
Vol 1418 ◽  
Author(s):  
Jean-Baptiste Guilbaud ◽  
Aline F. Miller ◽  
Alberto Saiani

ABSTRACTA synthetic strategy to couple selectively an ionic complementary thiol modified octapeptide, that is able to gel at low temperature, to the thermoresponsive polymer poly(N-isopropylacrylamide) (pNIPAAm) with controlled molecular weight and narrow polydispersity is described. The polymer was synthesized by atom transfer radical polymerization (ATRP) affording halogen functionalized chain ends. This allowed subsequent coupling to a thiol terminated ionic complementary octapeptide via nucleophile substitution. Results indicated that the peptide was covalently attached to the polymer and that both the coil-globule phase transition of pNIPAAm and the gelation properties of the peptide were retained in the conjugated product. This method provides a versatile route for the synthesis of a range of bioconjugate materials with controlled architecture and dual self-assembling and thermoresponsive behavior.


2011 ◽  
Vol 21 (46) ◽  
pp. 18653 ◽  
Author(s):  
Hua Bai ◽  
Kaixuan Sheng ◽  
Pengfei Zhang ◽  
Chun Li ◽  
Gaoquan Shi

2016 ◽  
Vol 127 ◽  
pp. 119-126 ◽  
Author(s):  
Ashraful Alam ◽  
Qingshi Meng ◽  
Ge Shi ◽  
Sherif Arabi ◽  
Jun Ma ◽  
...  

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