Bridging the Gap between the Nanostructural Organization and Macroscopic Interfacial Rheology of Amyloid Fibrils at Liquid Interfaces

Langmuir ◽  
2014 ◽  
Vol 30 (33) ◽  
pp. 10090-10097 ◽  
Author(s):  
Sophia Jordens ◽  
Patrick A. Rühs ◽  
Christine Sieber ◽  
Lucio Isa ◽  
Peter Fischer ◽  
...  
Keyword(s):  
Amyloid Fibrils ◽  
Interfacial Rheology ◽  
Liquid Interfaces ◽  
Nanostructural Organization

Interfacial Rheology of Hydrogen-Bonded Polymer Multilayers Assembled at Liquid Interfaces: Influence of Anchoring Energy and Hydrophobic Interactions

Langmuir ◽  
2016 ◽  
Vol 32 (24) ◽  
pp. 6089-6096 ◽  
Author(s):  
Sandrine Le Tirilly ◽  
Corentin Tregouët ◽  
Mathilde Reyssat ◽  
Stéphane Bône ◽  
Cédric Geffroy ◽  
...  
Keyword(s):  
Hydrophobic Interactions ◽  
Interfacial Rheology ◽  
Liquid Interfaces ◽  
Anchoring Energy ◽  
Hydrogen Bonded

scholarly journals Interfacial Rheology of Sterically Stabilized Colloids at Liquid Interfaces and Its Effect on the Stability of Pickering Emulsions

Langmuir ◽  
2017 ◽  
Vol 33 (17) ◽  
pp. 4107-4118 ◽  
Author(s):  
Rob Van Hooghten ◽  
Victoria E. Blair ◽  
Anja Vananroye ◽  
Andrew B. Schofield ◽  
Jan Vermant ◽  
...  
Keyword(s):  
Interfacial Rheology ◽  
Liquid Interfaces ◽  
Pickering Emulsions ◽  
The Stability

scholarly journals Nanoscale Surface Topography Modulates hIAPP Aggregation Pathways at Solid–Liquid Interfaces

2021 ◽  
Vol 22 (10) ◽  
pp. 5142
Author(s):  
Marcel Hanke ◽  
Yu Yang ◽  
Yuxin Ji ◽  
Guido Grundmeier ◽  
Adrian Keller
Keyword(s):  
Surface Topography ◽  
Amyloid Fibrils ◽  
Silicon Oxide ◽  
Ion Beam ◽  
Peptide Hormone ◽  
Time Lapse ◽  
Liquid Interfaces ◽  
Ripple Patterns ◽  
Amorphous Aggregation ◽  
Solid Liquid

The effects that solid–liquid interfaces exert on the aggregation of proteins and peptides are of high relevance for various fields of basic and applied research, ranging from molecular biology and biomedicine to nanotechnology. While the influence of surface chemistry has received a lot of attention in this context, the role of surface topography has mostly been neglected so far. In this work, therefore, we investigate the aggregation of the type 2 diabetes-associated peptide hormone hIAPP in contact with flat and nanopatterned silicon oxide surfaces. The nanopatterned surfaces are produced by ion beam irradiation, resulting in well-defined anisotropic ripple patterns with heights and periodicities of about 1.5 and 30 nm, respectively. Using time-lapse atomic force microscopy, the morphology of the hIAPP aggregates is characterized quantitatively. Aggregation results in both amorphous aggregates and amyloid fibrils, with the presence of the nanopatterns leading to retarded fibrillization and stronger amorphous aggregation. This is attributed to structural differences in the amorphous aggregates formed at the nanopatterned surface, which result in a lower propensity for nucleating amyloid fibrillization. Our results demonstrate that nanoscale surface topography may modulate peptide and protein aggregation pathways in complex and intricate ways.

Interfacial rheology of polymer/carbon nanotube films co-assembled at the oil/water interface

Soft Matter ◽  
2016 ◽  
Vol 12 (42) ◽  
pp. 8701-8709 ◽  
Author(s):  
Tao Feng ◽  
David A. Hoagland ◽  
Thomas P. Russell
Keyword(s):  
Thin Films ◽  
Carbon Nanotube ◽  
Interfacial Rheology ◽  
Water Interface ◽  
Liquid Interfaces ◽  
Composite Thin Films ◽  
Oil Water ◽  
Nanotube Films

Rheology of nanoscale composite thin-films at liquid/liquid interfaces.

Simultaneous Control of pH and Ionic Strength during Interfacial Rheology of β-Lactoglobulin Fibrils Adsorbed at Liquid/Liquid Interfaces

Langmuir ◽  
2012 ◽  
Vol 28 (34) ◽  
pp. 12536-12543 ◽  
Author(s):  
Patrick A. Rühs ◽  
Nathalie Scheuble ◽  
Erich J. Windhab ◽  
Raffaele Mezzenga ◽  
Peter Fischer
Keyword(s):  
Ionic Strength ◽  
Interfacial Rheology ◽  
Liquid Interfaces ◽  
Simultaneous Control ◽  
Β Lactoglobulin
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