Ionic Liquids Entrapped in Reverse Micelles as Nanoreactors for Bimolecular Nucleophilic Substitution Reaction. Effect of the Confinement on the Chloride Ion Availability

Langmuir ◽  
2014 ◽  
Vol 30 (41) ◽  
pp. 12130-12137 ◽  
Author(s):  
Diana Blach ◽  
Marcia Pessêgo ◽  
Juana J. Silber ◽  
N. Mariano Correa ◽  
Luis García-Río ◽  
...  
Keyword(s):  
Ionic Liquids ◽  
Nucleophilic Substitution ◽  
Substitution Reaction ◽  
Reverse Micelles ◽  
Chloride Ion ◽  
Nucleophilic Substitution Reaction

Facile aromatic nucleophilic substitution (SNAr) reactions in ionic liquids: an electrophile–nucleophile dual activation by [Omim]Br for the reaction

2016 ◽  
Vol 18 (20) ◽  
pp. 5580-5585 ◽  
Author(s):  
Xiao Zhang ◽  
Guo-ping Lu ◽  
Chun Cai
Keyword(s):  
Ionic Liquids ◽  
Nucleophilic Substitution ◽  
Substitution Reaction ◽  
Nucleophilic Substitution Reaction ◽  
Aromatic Nucleophilic Substitution ◽  
Aromatic Nucleophilic Substitution Reaction ◽  
Dual Activation

An aromatic nucleophilic substitution reaction in ionic liquids is promoted by an electrophile–nucleophile dual activation.

scholarly journals Synthesis of Carbohydrate Based Macrolactones and Their Applications as Receptors for Ion Recognition and Catalysis

Molecules ◽  
2021 ◽  
Vol 26 (11) ◽  
pp. 3394
Author(s):  
Surya B. Adhikari ◽  
Anji Chen ◽  
Guijun Wang
Keyword(s):  
Nucleophilic Substitution ◽  
Supramolecular Chemistry ◽  
Copper Sulfate ◽  
Substitution Reaction ◽  
Biological Properties ◽  
Anion Binding ◽  
Nucleophilic Substitution Reaction ◽  
Binding Properties ◽  
Intramolecular Nucleophilic Substitution ◽  
Leaving Groups

Glycomacrolactones exhibit many interesting biological properties, and they are also important in molecular recognitions and for supramolecular chemistry. Therefore, it is important to be able to access glycomacrocycles with different sizes and functionality. A new series of carbohydrate-based macrocycles containing triazole and lactone moieties have been designed and synthesized. The synthesis features an intramolecular nucleophilic substitution reaction for the macrocyclization step. In this article, the effect of some common sulfonate leaving groups is evaluated for macrolactonization. Using tosylate gave good selectivity for monolactonization products with good yields. Fourteen different macrocycles have been synthesized and characterized, of which eleven macrocycles are from cyclization of the C1 to C6 positions of N-acetyl D-glucosamine derivatives and three others from C2 to C6 cyclization of functionalized D-glucosamine derivatives. These novel macrolactones have unique structures and demonstrate interesting anion binding properties, especially for chloride. The macrocycles containing two triazoles form complexes with copper sulfate, and they are effective ligands for copper sulfate mediated azide-alkyne cycloaddition reactions (CuAAC). In addition, several macrocycles show some selectivity for different alkynes.

Lewis-Acid-Catalyzed Direct Nucleophilic Substitution Reaction of Alcohols for the Functionalization of Aromatic Amines

2019 ◽  
Vol 4 (4) ◽  
pp. 1371-1374 ◽  
Author(s):  
Onkar S. Nayal ◽  
Maheshwar S. Thakur ◽  
Rohit Rana ◽  
Rahul Upadhyay ◽  
Sushil K. Maurya
Keyword(s):  
Nucleophilic Substitution ◽  
Lewis Acid ◽  
Aromatic Amines ◽  
Substitution Reaction ◽  
Nucleophilic Substitution Reaction ◽  
Acid Catalyzed
Sign in / Sign up

Export Citation Format

Share Document