Synthesis and Swelling Behavior of pH-Responsive Polybase Brushes

Langmuir ◽  
2007 ◽  
Vol 23 (10) ◽  
pp. 5769-5778 ◽  
Author(s):  
S. Sanjuan ◽  
P. Perrin ◽  
N. Pantoustier ◽  
Y. Tran
Keyword(s):  
Swelling Behavior ◽  
Ph Responsive

Ph-Responsive Swelling Behavior of Collagen Complex Materials

2000 ◽  
Vol 28 (3) ◽  
pp. 255-262 ◽  
Author(s):  
Qiqing Zhang ◽  
Lingrong Liu ◽  
Haiying Zhou ◽  
Xiaoyu Wu ◽  
K. D. Yao
Keyword(s):  
Swelling Behavior ◽  
Complex Materials ◽  
Ph Responsive

scholarly journals Importance of pH in Synthesis of pH-Responsive Cationic Nano- and Microgels

Polymers ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 827
Author(s):  
Marco Annegarn ◽  
Maxim Dirksen ◽  
Thomas Hellweg
Keyword(s):  
Primary Amine ◽  
Strong Influence ◽  
Ph Value ◽  
Swelling Behavior ◽  
Ph Responsive ◽  
Strong Decrease ◽  
Negative Effects ◽  
Monomer Feed ◽  
Synthesis Yield

While cationic microgels are potentially useful for the transfection or transformation of cells, their synthesis has certain drawbacks regarding size, polydispersity, yield, and incorporation of the cationic comonomers. In this work, a range of poly(N-isopropylacrylamide) (PNIPAM) microgels with different amounts of the primary amine N-(3-aminopropyl)methacrylamide hydrochloride (APMH) as the cationic comonomer were synthesized. Moreover, the pH-value during reaction was varied for the synthesis of microgels with 10 mol% APMH-feed. The microgels were analyzed by means of their size, thermoresponsive swelling behavior, synthesis yield, polydispersity and APMH-incorporation. The copolymerization of APMH leads to a strong decrease in size and yield of the microgels, while less than one third of the nominal APMH monomer feed is incorporated into the microgels. With an increase of the reaction pH up to 9.5, the negative effects of APMH copolymerization were significantly reduced. Above this pH, synthesis was not feasible due to aggregation. The results show that the reaction pH has a strong influence on the synthesis of pH-responsive cationic microgels and therefore it can be used to tailor the microgel properties.

scholarly journals Dependence of the swelling behavior of a pH-responsive PEG-modified nanogel on the cross-link density

2011 ◽  
Vol 44 (3) ◽  
pp. 240-244 ◽  
Author(s):  
Goshu Tamura ◽  
Yuya Shinohara ◽  
Atsushi Tamura ◽  
Yusuke Sanada ◽  
Motoi Oishi ◽  
...  
Keyword(s):  
Swelling Behavior ◽  
Ph Responsive ◽  
Cross Link ◽  
Link Density ◽  
Cross Link Density ◽  
The Cross

Poly(Methacrylic Acid-g-Ethylene Glycol) Hydrogels as pH Responsive Biomedical Materials

1993 ◽  
Vol 331 ◽  
Author(s):  
Cristi L. Bell ◽  
Nicholas A. Peppas
Keyword(s):  
Hydrogen Bonding ◽  
Ethylene Glycol ◽  
Methacrylic Acid ◽  
Swelling Behavior ◽  
Ph Responsive ◽  
Responsive Membranes ◽  
Swelling Studies ◽  
Environmentally Sensitive ◽  
Responsive Hydrogels ◽  
Complexation Equilibrium

AbstractNovel graft copolymeric, pH responsive hydrogels have been synthesized by solution polymerization. Poly(methacrylic acid-g-ethylene glycol) hydrogels exhibit reversible complexation as a function of pH because of hydrogen bonding between the PEG grafts and the PMAA main chains. These gels are being developed as pH responsive membranes for use in biomedical applications. ATR-FTIR results indicate that there is hydrogen bonding occurring in membranes swollen under conditions favorable for complexation. Equilibrium swelling studies have shown that the pH of the surrounding environment has a significant effect on the swelling behavior of these membranes. The swelling behavior has also been shown to respond rapidly to changing pH conditions. P(MAA-g-EG) membranes also show pH sensitive permeability toward solutes as a result of this environmentally sensitive swelling.

Biodegradable pH-responsive polyacrylic acid derivative hydrogels with tunable swelling behavior for oral delivery of insulin

Polymer ◽  
2013 ◽  
Vol 54 (7) ◽  
pp. 1786-1793 ◽  
Author(s):  
Xiaoye Gao ◽  
Chaoliang He ◽  
Chunsheng Xiao ◽  
Xiuli Zhuang ◽  
Xuesi Chen
Keyword(s):  
Acid Derivative ◽  
Polyacrylic Acid ◽  
Oral Delivery ◽  
Swelling Behavior ◽  
Ph Responsive
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