Physicochemical Investigation of a Lipid with a New Core Structure for Gene Transfection:  2-Amino-3-hexadecyloxy-2-(hexadecyloxymethyl)propan-1-ol

Langmuir ◽  
2007 ◽  
Vol 23 (7) ◽  
pp. 3919-3926 ◽  
Author(s):  
Maria N. Antipina ◽  
Ingo Schulze ◽  
Bodo Dobner ◽  
Andreas Langner ◽  
Gerald Brezesinski
1983 ◽  
Vol 44 (C4) ◽  
pp. C4-37-C4-42 ◽  
Author(s):  
K. W. Lodge ◽  
A. Lapiccirella ◽  
N. Tomassini ◽  
S. L. Altmann

1988 ◽  
Vol 49 (C5) ◽  
pp. C5-251-C5-256 ◽  
Author(s):  
K. L. MERKLE ◽  
J. F. REDDY ◽  
C. L. WILEY ◽  
D. J. SMITH
Keyword(s):  

2020 ◽  
Vol 35 (10) ◽  
pp. 1000-1005
Author(s):  
Jian LI ◽  
◽  
Zhao-yi CHE ◽  
Ling-chao MO ◽  
Ming-gang HU ◽  
...  

2013 ◽  
Vol 29 (1) ◽  
pp. 3
Author(s):  
Qiong WANG ◽  
Jienan CHEN ◽  
Lin ZHANG

2020 ◽  
Author(s):  
Xuan Zhang ◽  
Yanjun Tong ◽  
Xiaomei Lyu ◽  
Jianfen Ye ◽  
Ruijin Yang

2018 ◽  
Vol 9 (1) ◽  
pp. 4-11 ◽  
Author(s):  
Aparna Bansal ◽  
Himanshu

Introduction: Gene therapy has emerged out as a promising therapeutic pave for the treatment of genetic and acquired diseases. Gene transfection into target cells using naked DNA is a simple and safe approach which has been further improved by combining vectors or gene carriers. Both viral and non-viral approaches have achieved a milestone to establish this technique, but non-viral approaches have attained a significant attention because of their favourable properties like less immunotoxicity and biosafety, easy to produce with versatile surface modifications, etc. Literature is rich in evidences which revealed that undoubtedly, non–viral vectors have acquired a unique place in gene therapy but still there are number of challenges which are to be overcome to increase their effectiveness and prove them ideal gene vectors. Conclusion: To date, tissue specific expression, long lasting gene expression system, enhanced gene transfection efficiency has been achieved with improvement in delivery methods using non-viral vectors. This review mainly summarizes the various physical and chemical methods for gene transfer in vitro and in vivo.


Author(s):  
Hideko Abe

This article discusses how the intersection of grammatical gender and social gender, entwined in the core structure of language, can be analyzed to understand the dynamic status of selfhood. After reviewing a history of scholarship that demonstrates this claim, the discussion analyzes the language practices of transgender individuals in Japan, where transgender identity is currently understood in terms of sei-dōitsusei-shōgai (gender identity disorder). Based on fieldwork conducted between 2011 and 2017, the analysis reveals how individuals identifying with sei-dōitsusei-shōgai negotiate subject positions by manipulating the specific indexical meanings attached to grammatical structures.


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