A Novel Layer-by-Layer Approach for the Fabrication of Conducting Polymer/RNA Multilayer Films for Controlled Release

Langmuir ◽  
2006 ◽  
Vol 22 (6) ◽  
pp. 2811-2815 ◽  
Author(s):  
Carmen L. Recksiedler ◽  
Bhavana A. Deore ◽  
Michael S. Freund
RSC Advances ◽  
2020 ◽  
Vol 10 (17) ◽  
pp. 10329-10337 ◽  
Author(s):  
Hanan Fael ◽  
A. Levent Demirel

Polyanion–nisin multilayer films exhibit antimicrobial activity by controlled release of nisin or as stable biofilm inhibiting coatings depending on polyanion.


2020 ◽  
Vol 2 (2) ◽  
pp. 741-750 ◽  
Author(s):  
Li Xu ◽  
Hailong Wang ◽  
Zihan Chu ◽  
Lawrence Cai ◽  
Haifeng Shi ◽  
...  

2012 ◽  
Vol 28 (10) ◽  
pp. 929-938 ◽  
Author(s):  
Katsuhiko SATO ◽  
Shigehiro TAKAHASHI ◽  
Jun-ichi ANZAI

2014 ◽  
Vol 1060 ◽  
pp. 45-49
Author(s):  
Kamonrak Cheewatanakornkool ◽  
Pornsak Sriamornsak

The main objective of this study was to fabricate biopolymer-based microbeads, providing enteric properties and controlled release of diclofenac sodium, using layer-by-layer technique. The calcium pectinate microbeads have been designed and coated with chitosan and pectin multilayers. Drug release was performed in simulate gastric fluid (pH 1.2) for 2 hours, followed by pH 6.8 buffer for 8 hours. The effects of chitosan concentration, number of layer and drying technique on drug release were investigated. The results showed that the calcium pectinate microbeads could be simply prepared by ionotropic gelation and then coated with chitosan and pectin solutions using layer-by-layer procedure. The diameter of the microbeads ranged from 800 to 1000 μm for air-dried samples and from 1 to 2 mm for freeze-dried samples. The freeze-dried microbeads had a rough surface and many pores inside, as observed by SEM. The microbeads coated with 4% chitosan/4% pectin revealed a slower drug release than those coated with 1% chitosan/4% pectin and demonstrated a controlled release pattern. Moreover, different drying techniques and numbers of layer also influenced drug release behavior of the prepared microbeads.


RSC Advances ◽  
2014 ◽  
Vol 4 (46) ◽  
pp. 24369-24376 ◽  
Author(s):  
Jiemin Zhao ◽  
Xiaoping Wang ◽  
Yanshen Kuang ◽  
Yufeng Zhang ◽  
Xiaowen Shi ◽  
...  

Alginate (ALG)–lysozyme (LZ) beads were fabricated by a cross-linking process. Negatively charged ALG and positively charged LZ were alternately deposited on the positively charged ALG–LZ beads via a layer-by-layer (LBL) self-assembly technique.


2008 ◽  
Vol 3 (2) ◽  
pp. 133-145 ◽  
Author(s):  
Chaoyang Wang ◽  
Shiqu Ye ◽  
Qilong Sun ◽  
Chengyi He ◽  
Weihua Ye ◽  
...  

2012 ◽  
Vol 571 ◽  
pp. 56-59
Author(s):  
Yu Fang Sha ◽  
Mei Zhao ◽  
Ming Quan Yang ◽  
Hai Xin Bai ◽  
Man Zhao

Biological multilayer films of redox polymer and horseradish peroxidase (HRP) were successfully assembled on a screen-printed carbon electrode using layer-by-layer (LBL) assembled method based on the electrostatic interaction. The screen-printed carbon electrode surface was modified by the positively charged redox polymer, and the negatively charged HRP by LBL method.


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