Photoresponsive Surfactants in Microgel Dispersions

Langmuir ◽  
2006 ◽  
Vol 22 (1) ◽  
pp. 101-105 ◽  
Author(s):  
Melanie Bradley ◽  
Brian Vincent ◽  
Nicholas Warren ◽  
Julian Eastoe ◽  
Ana Vesperinas
Keyword(s):  
Photoresponsive Surfactants

Photoresponsive Surfactants Exhibiting Unusually Large, Reversible Surface Tension Changes under Varying Illumination Conditions

Langmuir ◽  
2003 ◽  
Vol 19 (26) ◽  
pp. 10764-10773 ◽  
Author(s):  
Tiangang Shang ◽  
Kenneth A. Smith ◽  
T. Alan Hatton
Keyword(s):  
Surface Tension ◽  
Photoresponsive Surfactants

Adsorption of Photoresponsive Surfactants at Solid–Liquid Interfaces

Langmuir ◽  
2020 ◽  
Vol 36 (46) ◽  
pp. 14009-14018
Author(s):  
Maren Umlandt ◽  
David Feldmann ◽  
Emanuel Schneck ◽  
Svetlana A. Santer ◽  
Marek Bekir
Keyword(s):  
Liquid Interfaces ◽  
Photoresponsive Surfactants ◽  
Solid Liquid

scholarly journals Rapid controlled release by photo-irradiation using morphological changes in micelles formed by amphiphilic lophine dimers

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Masaaki Akamatsu ◽  
Kazuki Kobayashi ◽  
Hiroki Iwase ◽  
Yoshifumi Sakaguchi ◽  
Risa Tanaka ◽  
...  
Keyword(s):  
Controlled Release ◽  
Morphological Changes ◽  
Molecular Assembly ◽  
Active Components ◽  
Molecular Assemblies ◽  
On Demand ◽  
Photoresponsive Surfactants ◽  
Rapid Control ◽  
Ultraviolet Light Irradiation ◽  
Model Drug

AbstractPhoto-induced rapid control of molecular assemblies, such as micelles and vesicles, enables effective and on-demand release of drugs or active components, with applications such as drug delivery systems (DDS) and cosmetics. Thus far, no attempts to optimize the responsiveness of photoresponsive molecular assemblies have been published. We previously reported photoresponsive surfactants bearing a lophine dimer moiety that exhibit fast photochromism in confined spaces, such as inside a molecular assembly. However, rapid control of the micelle structures and solubilization capacity have not yet been demonstrated. In the present work, photo-induced morphological changes in micelles were monitored using in-situ small-angle neutron scattering (SANS) and UV/Vis absorption spectroscopy. An amphiphilic lophine dimer (3TEG-LPD) formed elliptical micelles. These were rapidly elongated by ultraviolet light irradiation, which could be reversed by dark treatment, both within 60 s. For a solution of 3TEG-LPD micelles solubilizing calcein as a model drug molecule, fluorescence and SANS measurements indicated rapid release of the incorporated calcein into the bulk solvent under UV irradiation. Building on these results, we investigated rapid controlled release via hierarchical chemical processes: photoisomerization, morphological changes in the micelles, and drug release. This rapid controlled release system allows for effective and on-demand DDS.

Sign in / Sign up

Export Citation Format

Share Document