Size-Selective Protein Adsorption to Polystyrene Surfaces by Self-Assembled Grafted Poly(ethylene Glycols) with Varied Chain Lengths

Langmuir ◽  
2005 ◽  
Vol 21 (19) ◽  
pp. 8774-8784 ◽  
Author(s):  
Dimitrios Lazos ◽  
Steffen Franzka ◽  
Mathias Ulbricht
Keyword(s):  
Protein Adsorption ◽  
Ethylene Glycols ◽  
Self Assembled ◽  
Poly Ethylene ◽  
Chain Lengths

Self-Assembled Monolayers as Models for Studying Protein Adsorption to Polymer Surfaces

1991 ◽  
Vol 237 ◽  
Author(s):  
Kevin L. Prime ◽  
George M. Whttesides
Keyword(s):  
Ethylene Oxide ◽  
Protein Adsorption ◽  
Organic Materials ◽  
Polymer Surfaces ◽  
Self Assembled Monolayers ◽  
Assembled Monolayers ◽  
Poly Ethylene Oxide ◽  
Self Assembled ◽  
Protein Resistant ◽  
Poly Ethylene

ABSTRACTSelf-assembled monolayers (SAMs) of functionalized alkanethiolates on gold are a well-characterized system for studying the interfacial properties of organic materials. We have used SAMs as models for the surfaces of organic polymers and used mem to study the adsorption of proteins onto organic materials. We have formed SAMs from mixtures of alkanethiols in which one alkanethiol is hydrophobic and the other is terminated by a short (2 ≤ n ≤ 17) oligomer of poly(ethylene oxide). These “mixed” SAMs effectively resist the adsorption of fibrinogen from moderately concentrated (1 mg/mL) solutions. Protein adsorption begins when < 5% of the accessible area of the surface consists of hydrophobic groups. These findings suggest that real protein-resistant monolayers must present an almost defect-free surface of oligo(ethylene oxide) groups in order to eliminate adsorption.

Star Shaped Poly(ethylene glycols) Yield Biocompatible Gene Delivery Systems

2015 ◽  
Vol 2 (4) ◽  
pp. 182-195 ◽  
Author(s):  
Jayanant Iemsam-Arng ◽  
Xiao Kong ◽  
Andreas G. Schatzlein ◽  
Ijeoma F. Uchegbu
Keyword(s):  
Gene Delivery ◽  
Delivery Systems ◽  
Ethylene Glycols ◽  
Poly Ethylene

Ch2-rocking vibrations and structural correlations of poly(ethylene glycols)

1959 ◽  
Vol 41 (138) ◽  
pp. 369-374 ◽  
Author(s):  
Horace F. White ◽  
Channing M. Lovell
Keyword(s):  
Ethylene Glycols ◽  
Poly Ethylene

Poly(ethylene oxide) Grafted to Silicon Surfaces: Grafting Density and Protein Adsorption

1998 ◽  
Vol 31 (15) ◽  
pp. 5059-5070 ◽  
Author(s):  
Susan J. Sofia ◽  
V. Premnath ◽  
Edward W. Merrill
Keyword(s):  
Ethylene Oxide ◽  
Protein Adsorption ◽  
Silicon Surfaces ◽  
Grafting Density ◽  
Poly Ethylene Oxide ◽  
Poly Ethylene
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