The Nature of Alkanethiol Self-Assembled Monolayer Adsorption on Sputtered Gold Substrates

Langmuir ◽  
2004 ◽  
Vol 20 (19) ◽  
pp. 8172-8182 ◽  
Author(s):  
C. O'Dwyer ◽  
G. Gay ◽  
B. Viaris de Lesegno ◽  
J. Weiner
Langmuir ◽  
2005 ◽  
Vol 21 (4) ◽  
pp. 1661-1661 ◽  
Author(s):  
C. O'Dwyer ◽  
G. Gay ◽  
B. Viaris de Lesegno ◽  
J. Weiner

2009 ◽  
Vol 81 (16) ◽  
pp. 6960-6965 ◽  
Author(s):  
Rajesh Sardar ◽  
Christopher A. Beasley ◽  
Royce W. Murray

Langmuir ◽  
2009 ◽  
Vol 25 (2) ◽  
pp. 931-938 ◽  
Author(s):  
Andrew P. Henderson ◽  
Lalitesh N. Seetohul ◽  
Andrew K. Dean ◽  
Paul Russell ◽  
Stela Pruneanu ◽  
...  

2007 ◽  
Vol 111 (1) ◽  
pp. 286-293 ◽  
Author(s):  
Aloke Kanjilal ◽  
Luca Ottaviano ◽  
Valeria Di Castro ◽  
Marco Beccari ◽  
Maria Grazia Betti ◽  
...  

Coatings ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. 1014
Author(s):  
Zijiao Zhang ◽  
Ni Kou ◽  
Weilong Ye ◽  
Shuo Wang ◽  
Jiaju Lu ◽  
...  

Background: Infection that is related to implanted biomaterials is a serious issue in the clinic. Antimicrobial peptides (AMPs) have been considered as an ideal alternative to traditional antibiotic drugs, for the treatment of infections, while some problems, such as aggregation and protein hydrolysis, are still the dominant concerns that compromise their antimicrobial efficiency in vivo. Methods: In this study, antimicrobial peptides underwent self-assembly on gold substrates, forming good antibacterial surfaces, with stable antibacterial behavior. The antimicrobial ability of AMPs grafted on the surfaces, with or without glycine spaces or a primer layer, was evaluated. Results: Specifically, three Pac-525 derivatives, namely, Ac-CGn-KWRRWVRWI-NH2 (n = 0, 2, or 6) were covalently grafted onto gold substrates via the self-assembling process for inhibiting the growth of Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli). Furthermore, the alkanethiols HS(CH)10SH were firstly self-assembled into monolayers, as a primer layer (SAM-SH) for the secondary self-assembly of Pac-525 derivatives, to effectively enhance the bactericidal performance of the grafted AMPs. The -(CH)10-S-S-G6Pac derivative was highly effective against S. aureus and E. coli, and reduced the viable amount of E. coli and S. aureus to 0.4% and 33.2%, respectively, after 24 h of contact. In addition, the immobilized AMPs showed good biocompatibility, promoting bone marrow stem cell proliferation. Conclusion: the self-assembled monolayers of the Pac-525 derivatives have great potential as a novel therapeutic method for the treatment of implanted biomaterial infections.


2014 ◽  
Vol 18 (8) ◽  
pp. 2289-2295 ◽  
Author(s):  
Zuzana Nováková ◽  
Renáta Oriňáková ◽  
Andrea Straková Fedorková ◽  
Andrej Oriňák

2019 ◽  
Vol 3 (4) ◽  
pp. 636-639 ◽  
Author(s):  
Esther Frederick ◽  
Travis W. Shaw ◽  
Matthew G. Frith ◽  
Steven L. Bernasek

Carbene based self-assembled monolayers are demonstrated to be effective supports for forming highly stable surface-mounted metal–organic frameworks on gold substrates.


Langmuir ◽  
1998 ◽  
Vol 14 (26) ◽  
pp. 7456-7462 ◽  
Author(s):  
Katsuhiko Fujita ◽  
Masahiko Hara ◽  
Hiroyuki Sasabe ◽  
Wolfgang Knoll ◽  
Kazuma Tsuboi ◽  
...  

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