Competitive Adsorption of High Molecular Weight Kininogen and Fibrinogen from Binary Mixtures to Glass Surface

Langmuir ◽  
1995 ◽  
Vol 11 (10) ◽  
pp. 4001-4007 ◽  
Author(s):  
P. Dejardin ◽  
P. ten Hove ◽  
X. J. Yu ◽  
J. L. Brash
Keyword(s):  
Molecular Weight ◽  
High Molecular Weight ◽  
Binary Mixtures ◽  
Glass Surface ◽  
Competitive Adsorption ◽  
High Molecular Weight Kininogen

High-molecular-weight kininogen preadsorbed to glass surface markedly reduces neutrophil adhesion

Biomaterials ◽  
2000 ◽  
Vol 21 (4) ◽  
pp. 405-414 ◽  
Author(s):  
Lin-Yue L Yung ◽  
Florencia Lim ◽  
Mohammad M.H Khan ◽  
Satya P Kunapuli ◽  
Leonard Rick ◽  
...  
Keyword(s):  
Molecular Weight ◽  
High Molecular Weight ◽  
Glass Surface ◽  
Neutrophil Adhesion ◽  
High Molecular Weight Kininogen

The Contact Phase of Blood Coagulation in Diabetes Mellitus and in Patients with Vasculopathy

1984 ◽  
Vol 52 (03) ◽  
pp. 221-223 ◽  
Author(s):  
M Christe ◽  
P Gattlen ◽  
J Fritschi ◽  
B Lämmle ◽  
W Berger ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Molecular Weight ◽  
Blood Coagulation ◽  
High Molecular Weight ◽  
Negative Correlation ◽  
Factor Xii ◽  
C1 Inhibitor ◽  
High Molecular Weight Kininogen ◽  
Contact Phase ◽  
Α2 Macroglobulin

SummaryThe contact phase has been studied in diabetics and patients with macroangiopathy. Factor XII and high molecular weight kininogen (HMWK) are normal. C1-inhibitor and also α2-macroglobulin are significantly elevated in diabetics with complications, for α1-macroglobulin especially in patients with nephropathy, 137.5% ± 36.0 (p <0.001). C1-inhibitor is also increased in vasculopathy without diabetes 113.2 ± 22.1 (p <0.01).Prekallikrein (PK) is increased in all patients’ groups (Table 2) as compared to normals. PK is particularly high (134% ± 32) in 5 diabetics without macroangiopathy but with sensomotor neuropathy. This difference is remarkable because of the older age of diabetics and the negative correlation of PK with age in normals.

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