Ultraviolet spectroscopic estimation of microenvironments and bitter tastes of oxyphenonium bromide in cyclodextrin solutions

1999 ◽  
Vol 88 (8) ◽  
pp. 759-762 ◽  
Author(s):  
Noriaki Funasaki ◽  
Ryusaku Kawaguchi ◽  
Sakae Hada ◽  
Saburo Neya
Keyword(s):  
Oxyphenonium Bromide

scholarly journals Stability-Indicating Method for Determination of Oxyphenonium Bromide and Its Degradation Product by High-Performance Liquid Chromatography

2007 ◽  
Vol 90 (5) ◽  
pp. 1250-1257 ◽  
Author(s):  
Alaa EL-Gindy ◽  
Samy Emara ◽  
Heba Shaaban
Keyword(s):  
Degradation Product ◽  
High Performance ◽  
Potassium Dihydrogen Phosphate ◽  
Order Rate Constant ◽  
High Performance Liquid Chromatographic ◽  
Hplc Method ◽  
Dihydrogen Phosphate ◽  
Stability Indicating Method ◽  
Oxyphenonium Bromide

Abstract A high-performance liquid chromatographic (HPLC) method was developed for determination of oxyphenonium bromide (OX) and its degradation product. The method was based on the HPLC separation of OX from its degradation product, using a cyanopropyl column at ambient temperature with mobile phase of acetonitrile25 mM potassium dihydrogen phosphate, pH 3.4 (50 + 50, v/v). UV detection at 222 nm was used for quantitation based on peak area. The method was applied to the determination of OX and its degradation product in tablets. The proposed method was also used to investigate the kinetics of the acidic and alkaline degradation of OX at different temperatures, and the apparent pseudo first-order rate constant, half-life, and activation energy were calculated. The pH-rate profile of the degradation of OX in Britton-Robinson buffer solutions within the pH range 212 was studied.

scholarly journals THE ANTISIALOGOGUE EFFECT OF ANTRENYL (OXYPHENONIUM BROMIDE)

1955 ◽  
Vol 27 (11) ◽  
pp. 519-524 ◽  
Author(s):  
WILLIAM W. MUSHIN ◽  
ADAM S. ADAMS
Keyword(s):  
Oxyphenonium Bromide

scholarly journals Comparative study of the bronchodilating effects of (−)− and (+)- oxyphenonium bromide.

1988 ◽  
Vol 25 (6) ◽  
pp. 683-687 ◽  
Author(s):  
KG Feitsma ◽  
DS Postma ◽  
GH Koeter ◽  
GD Nossent ◽  
BF Brenth ◽  
...  
Keyword(s):  
Comparative Study ◽  
Oxyphenonium Bromide

Hydration Effect on Molecular Conformation of Oxyphenonium Bromide

2000 ◽  
Vol 104 (44) ◽  
pp. 10412-10418 ◽  
Author(s):  
Noriaki Funasaki ◽  
Hiroshi Yamaguchi ◽  
Seiji Ishikawa ◽  
Saburo Neya
Keyword(s):  
Molecular Conformation ◽  
Hydration Effect ◽  
Oxyphenonium Bromide

Coexistence of Two 1:1 Complexes of Oxyphenonium Bromide and α-Cyclodextrin

2003 ◽  
Vol 76 (5) ◽  
pp. 903-911 ◽  
Author(s):  
Noriaki Funasaki ◽  
Hiroshi Yamaguchi ◽  
Seiji Ishikawa ◽  
Saburo Neya
Keyword(s):  
Oxyphenonium Bromide
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