Recombination and Escape of Ions in High-Energy Charged Particle Tracks:  Computer Simulation Compared with the Analytical Model of Jaffé

1997 ◽  
Vol 101 (43) ◽  
pp. 8135-8139 ◽  
Author(s):  
Witold M. Bartczak ◽  
Laurens D. A. Siebbeles ◽  
Andries Hummel
Keyword(s):  
Computer Simulation ◽  
Charged Particle ◽  
Analytical Model ◽  
High Energy ◽  
Particle Tracks

High throughput on-chip analysis of high-energy charged particle tracks using lensfree imaging

2015 ◽  
Vol 106 (15) ◽  
pp. 151107 ◽  
Author(s):  
Wei Luo ◽  
Faizan Shabbir ◽  
Chao Gong ◽  
Cagatay Gulec ◽  
Jeremy Pigeon ◽  
...  
Keyword(s):  
Charged Particle ◽  
High Throughput ◽  
High Energy ◽  
Lensfree Imaging ◽  
Particle Tracks ◽  
On Chip ◽  
Chip Analysis

Influence of Ultrasound on the Formation of High-energy Particle Tracks in a Liquid-hydrogen Bubble Chamber

1969 ◽  
Vol 99 (9) ◽  
pp. 149-151
Author(s):  
V.A. Akulichev ◽  
L.R. Gavrilov ◽  
V.G. Grebinnik ◽  
V.A. Zhukov ◽  
G. Libman ◽  
...  
Keyword(s):  
Bubble Chamber ◽  
High Energy ◽  
Liquid Hydrogen ◽  
High Energy Particle ◽  
Hydrogen Bubble ◽  
Hydrogen Bubble Chamber ◽  
Energy Particle ◽  
Particle Tracks

scholarly journals Charged Particle and Conventional Radiotherapy: Current Implications as Partner for Immunotherapy

Cancers ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 1468
Author(s):  
Damiënne Marcus ◽  
Relinde I. Y. Lieverse ◽  
Carmen Klein ◽  
Amir Abdollahi ◽  
Philippe Lambin ◽  
...  
Keyword(s):  
Charged Particle ◽  
Clinical Success ◽  
Immune Therapy ◽  
Locally Advanced ◽  
Optimal Dose ◽  
High Energy ◽  
Advanced Lung Cancer ◽  
Antitumor Effects ◽  
Immunological Effects ◽  
Tumor Immunogenicity

Radiotherapy (RT) has been shown to interfere with inflammatory signals and to enhance tumor immunogenicity via, e.g., immunogenic cell death, thereby potentially augmenting the therapeutic efficacy of immunotherapy. Conventional RT consists predominantly of high energy photon beams. Hypofractionated RT regimens administered, e.g., by stereotactic body radiation therapy (SBRT), are increasingly investigated in combination with cancer immunotherapy within clinical trials. Despite intensive preclinical studies, the optimal dose per fraction and dose schemes for elaboration of RT induced immunogenic potential remain inconclusive. Compared to the scenario of combined immune checkpoint inhibition (ICI) and RT, multimodal therapies utilizing other immunotherapy principles such as adoptive transfer of immune cells, vaccination strategies, targeted immune-cytokines and agonists are underrepresented in both preclinical and clinical settings. Despite the clinical success of ICI and RT combination, e.g., prolonging overall survival in locally advanced lung cancer, curative outcomes are still not achieved for most cancer entities studied. Charged particle RT (PRT) has gained interest as it may enhance tumor immunogenicity compared to conventional RT due to its unique biological and physical properties. However, whether PRT in combination with immune therapy will elicit superior antitumor effects both locally and systemically needs to be further investigated. In this review, the immunological effects of RT in the tumor microenvironment are summarized to understand their implications for immunotherapy combinations. Attention will be given to the various immunotherapeutic interventions that have been co-administered with RT so far. Furthermore, the theoretical basis and first evidences supporting a favorable immunogenicity profile of PRT will be examined.

Very-high-energy light charged-particle production near 0° in heavy-ion collisions, 9≤E/A≤40 MeV

1990 ◽  
Vol 42 (4) ◽  
pp. 1519-1529 ◽  
Author(s):  
S. Shaheen ◽  
F. D. Becchetti ◽  
D. A. Roberts ◽  
J. W. Jänecke ◽  
R. L. Stern ◽  
...  
Keyword(s):  
Charged Particle ◽  
Heavy Ion Collisions ◽  
Particle Production ◽  
Heavy Ion ◽  
High Energy ◽  
Light Charged Particle ◽  
Ion Collisions ◽  
Charged Particle Production ◽  
Very High Energy ◽  
Very High

Computersimulation der Rückstreuung schneller schwerer Ionen an einkristallinen (001)-und (111̅)-Goldoberflächen / Computer Simulation of the Backscattering of High Energy Ions from (001)- and (111̅)-surfaces of Au-Single Crystals

1976 ◽  
Vol 31 (3-4) ◽  
pp. 316-326 ◽  
Author(s):  
H. Schmidt ◽  
K. Güttner
Keyword(s):  
Computer Simulation ◽  
Computer Program ◽  
Single Crystals ◽  
Grazing Incidence ◽  
High Energy ◽  
Rapid Decrease ◽  
Fcc Lattice ◽  
High Energy Ions

A computer program for following the trajectories of high energy ions in an fcc-lattice has been written to evaluate the reflection rate of high energy ions with grazing incidence to (001)- and (111̅)-Au-surfaces. The calculation yields a rapid decrease of the reflection rate for penetration directions close to low-index atomic planes. It can be shown that this result is caused by channeling of the ions between the atomic planes.

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