Chiral Recognition between Dissymmetric Tb- and Eu(pyridine-2,6-dicarboxylate)33-Complexes and Fe(III) Proteins in Aqueous Solution. Luminescence Quenching by Cytochromecfrom Horse Heart and Cytochromec-550 fromThiobacillus versutusand Its Lys14 → Glu and Lys99 → Glu Mutants

1996 ◽  
Vol 100 (45) ◽  
pp. 17957-17969 ◽  
Author(s):  
Stefan C. J. Meskers ◽  
Marcellus Ubbink ◽  
Gerard W. Canters ◽  
Harry P. J. M. Dekkers
Keyword(s):  
Aqueous Solution ◽  
Chiral Recognition ◽  
Luminescence Quenching

Enantioselective Recognition of Chiral Guests by the Water-Soluble Chiral Keplerate {Mo132} Spherical Capsule with 30 Inner Lactate Ligands

2019 ◽  
Author(s):  
Nancy Watfa ◽  
Weimin Xuan ◽  
Zoe Sinclair ◽  
Robert Pow ◽  
Yousef Abul-Haija ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Chiral Recognition ◽  
Association Constants ◽  
Water Soluble ◽  
Enantioselective Recognition ◽  
H Nmr ◽  
Dosy Nmr ◽  
Spherical Capsule ◽  
Surface Pores ◽  
Guest Chemistry

Investigations of chiral host guest chemistry are important to explore recognition in confined environments. Here, by synthesizing water-soluble chiral porous nanocapsule based on the inorganic metal-oxo Keplerate-type cluster, {Mo<sub>132</sub>} with chiral lactate ligands with the composition [Mo<sub>132</sub>O<sub>372</sub>(H<sub>2</sub>O)<sub>72</sub>(<i>x-</i>Lactate)<sub>30</sub>]<sup>42-</sup> (<i>x</i> = D or L), it was possible to study the interaction with a chiral guest, L/D-carnitine and (<i>R</i>/<i>S</i>)-2-butanol in aqueous solution. The enantioselective recognition was studied by quantitative <sup>1</sup>H NMR and <sup>1</sup>H DOSY NMR which highlighted that the chiral recognition is regulated by two distinct sites. Differences in the association constants (K) of L- and D-carnitine, which, due to their charge, are generally restricted from entering the interior of the host, are observed, indicating that their recognition predominantly occurs at the surface pores of the structure. Conversely, a larger difference in association constants (K<i><sub>S</sub></i>/K<i><sub>R</sub></i> = 3) is observed for recognition within the capsule interior of (<i>R</i>)- and (<i>S</i>)-2-butanol.

Chiral recognition in aqueous solution. Search for water-soluble chiral hosts with apolar binding sites

1986 ◽  
Vol 51 (17) ◽  
pp. 3270-3278 ◽  
Author(s):  
Yves Rubin ◽  
Klaus Dick ◽  
Francois Diederich ◽  
Taxiarchis M. Georgiadis
Keyword(s):  
Aqueous Solution ◽  
Binding Sites ◽  
Chiral Recognition ◽  
Water Soluble
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