Crystal Structure of a Hydrogen Sulfide Sorption Complex of Dehydrated Partially Cobalt(II)-Exchanged Zeolite A

1996 ◽  
Vol 100 (20) ◽  
pp. 8373-8377 ◽  
Author(s):  
Young Hoon Yeom ◽  
Yang Kim ◽  
Karl Seff
Keyword(s):  
Crystal Structure ◽  
Hydrogen Sulfide ◽  
Zeolite A

scholarly journals Specificity of Human Sulfiredoxin for Reductant and Peroxiredoxin Oligomeric State

Antioxidants ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 946
Author(s):  
Tom E. Forshaw ◽  
Julie A. Reisz ◽  
Kimberly J. Nelson ◽  
Rajesh Gumpena ◽  
J. Reed Lawson ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Antioxidant Enzymes ◽  
Hydrogen Sulfide ◽  
Active Site ◽  
Relative Efficacy ◽  
Oligomeric Structure ◽  
Cellular Functions ◽  
Oligomeric State ◽  
Structural Requirements ◽  
First Time

Human peroxiredoxins (Prx) are a family of antioxidant enzymes involved in a myriad of cellular functions and diseases. During the reaction with peroxides (e.g., H2O2), the typical 2-Cys Prxs change oligomeric structure between higher order (do)decamers and disulfide-linked dimers, with the hyperoxidized inactive state (-SO2H) favoring the multimeric structure of the reduced enzyme. Here, we present a study on the structural requirements for the repair of hyperoxidized 2-Cys Prxs by human sulfiredoxin (Srx) and the relative efficacy of physiological reductants hydrogen sulfide (H2S) and glutathione (GSH) in this reaction. The crystal structure of the toroidal Prx1-Srx complex shows an extended active site interface. The loss of this interface within engineered Prx2 and Prx3 dimers yielded variants more resistant to hyperoxidation and repair by Srx. Finally, we reveal for the first time Prx isoform-dependent use of and potential cooperation between GSH and H2S in supporting Srx activity.

Crystal structure of dehydrated cesium- and thallium-exchanged zeolite A

1979 ◽  
Vol 83 (16) ◽  
pp. 2166-2169 ◽  
Author(s):  
V. Subramanian ◽  
Karl. Seff
Keyword(s):  
Crystal Structure ◽  
Zeolite A

Crystal structure of a hydrogen sulfide sorption complex of zeolite LTA

Zeolites ◽  
1996 ◽  
Vol 17 (5-6) ◽  
pp. 495-500 ◽  
Author(s):  
Young Hoon Yeom ◽  
Yang Kim ◽  
Young Wook Han ◽  
Karl Seff
Keyword(s):  
Crystal Structure ◽  
Hydrogen Sulfide ◽  
Zeolite Lta
Sign in / Sign up

Export Citation Format

Share Document