Effects of Photoinduced Electron Transfer on the Rational Design of Molecular Fluorescence Switch

2009 ◽  
Vol 113 (6) ◽  
pp. 2594-2602 ◽  
Author(s):  
Ruili Zhang ◽  
Yishi Wu ◽  
Zhongliang Wang ◽  
Wei Xue ◽  
Hongbing Fu ◽  
...  
Keyword(s):  
Electron Transfer ◽  
Photoinduced Electron Transfer ◽  
Rational Design ◽  
Fluorescence Switch ◽  
Molecular Fluorescence

Rational design of a boron-dipyrromethene-based fluorescent probe for detecting Pd2+ sensitively and selectively in aqueous media

The Analyst ◽  
2019 ◽  
Vol 144 (4) ◽  
pp. 1260-1264 ◽  
Author(s):  
Yannan Li ◽  
Li Yang ◽  
Mengqi Du ◽  
Guanjun Chang
Keyword(s):  
Electron Transfer ◽  
Fluorescent Probe ◽  
Photoinduced Electron Transfer ◽  
Rational Design ◽  
Aqueous Media ◽  
Transfer Mechanism ◽  
Electron Transfer Mechanism ◽  
Boron Dipyrromethene

A novel fluorescent probe for Pd2+ based on the BODIPY fluorophore exploiting the PET (Photoinduced Electron Transfer) mechanism was designed and successfully synthesized.

Rational Design Principle for Modulating Fluorescence Properties of Fluorescein-Based Probes by Photoinduced Electron Transfer

2003 ◽  
Vol 125 (28) ◽  
pp. 8666-8671 ◽  
Author(s):  
Tetsuo Miura ◽  
Yasuteru Urano ◽  
Kumi Tanaka ◽  
Tetsuo Nagano ◽  
Kei Ohkubo ◽  
...  
Keyword(s):  
Electron Transfer ◽  
Photoinduced Electron Transfer ◽  
Rational Design ◽  
Design Principle ◽  
Fluorescence Properties

Rational Design of High-Performance Donor–Linker–Acceptor Hybrids Using a Schiff Base for Enabling Photoinduced Electron Transfer

2019 ◽  
Vol 92 (2) ◽  
pp. 2019-2026 ◽  
Author(s):  
Hao-Hua Deng ◽  
Kai-Yuan Huang ◽  
Shao-Bin He ◽  
Li-Ping Xue ◽  
Hua-Ping Peng ◽  
...  
Keyword(s):  
Electron Transfer ◽  
Schiff Base ◽  
Photoinduced Electron Transfer ◽  
High Performance ◽  
Rational Design

Rational design of novel photoinduced electron transfer type fluorescent probes for sodium cation

Tetrahedron ◽  
2004 ◽  
Vol 60 (49) ◽  
pp. 11067-11073 ◽  
Author(s):  
Suguru Kenmoku ◽  
Yasuteru Urano ◽  
Koujirou Kanda ◽  
Hirotatsu Kojima ◽  
Kazuya Kikuchi ◽  
...  
Keyword(s):  
Electron Transfer ◽  
Fluorescent Probes ◽  
Photoinduced Electron Transfer ◽  
Rational Design ◽  
Sodium Cation

Rational design of signal-on biosensors by using photoinduced electron transfer between Ag nanoclusters and split G-quadruplex halves–hemin complexes

2014 ◽  
Vol 50 (91) ◽  
pp. 14221-14224 ◽  
Author(s):  
Kai Zhang ◽  
Ke Wang ◽  
Xue Zhu ◽  
Yun Gao ◽  
Minhao Xie
Keyword(s):  
Electron Transfer ◽  
Photoinduced Electron Transfer ◽  
Rational Design ◽  
Sensing Platform ◽  
G Quadruplex ◽  
Ag Nanoclusters

Photoinduced electron transfer (PET) between DNA–Ag nanoclusters (AgNCs) and G-quadruplex halves–hemin has been used for building a new sensing platform for the signal-on detection of adenosine and RNA.

Computationally Assisted Design of High Signal-to-Noise Photoinduced Electron Transfer-Based Voltage-Sensitive Dyes

2020 ◽  
Author(s):  
Rishikesh Kulkarni ◽  
Anneliese Gest ◽  
Chun Kei Lam ◽  
Benjamin Raliski ◽  
Feroz James ◽  
...  
Keyword(s):  
Electron Transfer ◽  
Dft Calculations ◽  
Photoinduced Electron Transfer ◽  
Density Functional ◽  
Embryonic Stem ◽  
High Sensitivity ◽  
Md Simulations ◽  
High Signal ◽  
Signal To Noise ◽  
Green Fluorescent

<p>High signal-to-noise optical voltage indicators will enable simultaneous interrogation of membrane potential in large ensembles of neurons. However, design principles for voltage sensors with high sensitivity and brightness remain elusive, limiting the applicability of voltage imaging. In this paper, we use molecular dynamics (MD) simulations and density functional theory (DFT) calculations to guide the design of a bright and sensitive green-fluorescent voltage-sensitive fluorophore, or VoltageFluor (VF dye), that uses photoinduced electron transfer (PeT) as a voltage-sensing mechanism. MD simulations predict an 11% increase in sensitivity due to membrane orientation, while DFT calculations predict an increase in fluorescence quantum yield, but a decrease in sensitivity due to a decrease in rate of PeT. We confirm these predictions by synthesizing a new VF dye and demonstrating that it displays the expected improvements by doubling the brightness and retaining similar sensitivity to prior VF dyes. Combining theoretical predictions and experimental validation has resulted in the synthesis of the highest signal-to-noise green VF dye to date. We use this new voltage indicator to monitor the electrophysiological maturation of human embryonic stem cell-derived medium spiny neurons. </p>

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