1H and 7Li NMR Pulsed Gradient Spin Echo Measurements and Multiscale Modeling of the Water and Ionic Mobility within Aqueous Dispersions of Charged Anisotropic Nanoparticles

2008 ◽  
Vol 112 (31) ◽  
pp. 11893-11900 ◽  
Author(s):  
Patrice Porion ◽  
Anne Marie Faugère ◽  
Alfred Delville
2001 ◽  
Vol 105 (13) ◽  
pp. 2546-2550 ◽  
Author(s):  
Hiroshi Kataoka ◽  
Yuria Saito ◽  
Tetsuo Sakai ◽  
Shigehito Deki ◽  
Takeyoshi Ikeda

Author(s):  
Vitthal S. Kulkarni ◽  
Wayne H. Anderson ◽  
Rhoderick E. Brown

The biological significance of the sphingomyelins (SM) and monoglycosylated sphingolipids like galactosylceramides (GalCer) are well documented Our recent investigation showed tubular bilayers in the aqueous dispersions of N-nervonoyl GalCer [N-(24:lΔ15,cls) GalCer] (a major fatty acyl moiety of natural GalCer). To determine the influence of lipid head groups on the resulting mesophasic morphology, we investigated microstructural self-assemblies of N-nervonoyl-SM [N-(24:1 Δ15,cls) SM; the second most abundant sphingomyelin in mammalian cell membranes], 1- palmitoyl-2-nervonoyl phosphatidylcholine [PNPC] (the lipid species with the same acyl chain configuration as in N-(24: 1) GalCer) and also compared it with egg-SM by freeze-fracture EM.Procedures for synthesizing and purifying N-(24:1) GalCer, N-(24:1) SM, and PNPC have been reported . Egg-SM was purchased from Avanti Polar Lipids, Alabaster AL. All lipids were >99% pure as checked by thin layer chromatography. Lipid dispersions were prepared by hydrating dry lipid with phosphate buffer (pH 6.6) at 80-90°C (3-5 min), vigorously vortexing (1 min) and repeating this procedure for three times prior to three freeze-thaw cycles.


1999 ◽  
Vol 09 (PR10) ◽  
pp. Pr10-49-Pr10-51
Author(s):  
W. G. Clark ◽  
F. Lefloch ◽  
M. E. Hanson ◽  
W. H. Wong

1978 ◽  
Vol 39 (C6) ◽  
pp. C6-1182-C6-1183
Author(s):  
H. R. Foster ◽  
P. Cooke ◽  
D. H. Chaplin ◽  
P. Lynam ◽  
D. E. Swan ◽  
...  
Keyword(s):  

Author(s):  
TM Ernst ◽  
N Raabe ◽  
D Schwinge ◽  
C Schramm ◽  
MG Kaul ◽  
...  
Keyword(s):  

1989 ◽  
Vol 28 (06) ◽  
pp. 234-242 ◽  
Author(s):  
U. Sechtem ◽  
Sabine Langkamp ◽  
M. Jungehülsing ◽  
H. H. Hilger ◽  
H. Schicha ◽  
...  

Fortyfour patients with recent cardiac catheterization because of recurrent chest pain after coronary artery bypass surgery were studied by magnetic resonance imaging to evaluate graft patency. To assess the efficacy of this non-invasive method 92 coronary artery bypass grafts were examined by the spin-echo technique. ECG-gated transversal sections were acquired between the diaphragm and the aortic arch. The specificity of magnetic resonance imaging was 83% (48/58) for patent grafts. However, the sensitivity in the detection of occluded bypasses was only 56% (19/34). Despite the good specificity, clinical applications of this method are limited because of its low sensitivity.


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