Dominance of Silylene Chemistry in the Decomposition of Monomethylsilane in the Presence of a Heated Metal Filament

2014 ◽  
Vol 118 (22) ◽  
pp. 3866-3874 ◽  
Author(s):  
R. Toukabri ◽  
Y. J. Shi
Keyword(s):  
Metal Filament ◽  
Heated Metal

SIZE AND SHAPE OF CRYSTAL FACES ON HEATED METAL TIPS

1984 ◽  
Vol 45 (C9) ◽  
pp. C9-29-C9-37
Author(s):  
Vu Thien Binh ◽  
M. Drechsler
Keyword(s):  
Size And Shape ◽  
Heated Metal

Study on Threshold Behavior of Operation Voltage in Metal Filament-Based Polymer Memory

2007 ◽  
Vol 111 (27) ◽  
pp. 7756-7760 ◽  
Author(s):  
Won-Jae Joo ◽  
Tae-Lim Choi ◽  
Kwang-Hee Lee ◽  
Youngsu Chung
Keyword(s):  
Threshold Behavior ◽  
Metal Filament ◽  
Polymer Memory

High-temperature strength testing of directly resistance-heated metal specimens

1989 ◽  
Vol 7 (3) ◽  
pp. 145-151
Author(s):  
F. Mitter ◽  
J. Schrank ◽  
E. Werner ◽  
E. Pink
Keyword(s):  
High Temperature ◽  
High Temperature Strength ◽  
Strength Testing ◽  
Heated Metal

scholarly journals The Cutaneous Inflammatory Response to Thermal Burn Injury in a Murine Model

2019 ◽  
Vol 20 (3) ◽  
pp. 538 ◽  
Author(s):  
Zabeen Lateef ◽  
Gabriella Stuart ◽  
Nicola Jones ◽  
Andrew Mercer ◽  
Stephen Fleming ◽  
...  
Keyword(s):  
Inflammatory Response ◽  
Murine Model ◽  
Burn Injury ◽  
Thermal Burn ◽  
Dermal Thickness ◽  
Collagen Iii ◽  
M1 Phenotype ◽  
Macrophage Populations ◽  
Inflammatory Response To Injury ◽  
Heated Metal

Many burn interventions aim to target the inflammatory response as a means of enhancing healing or limiting hypertrophic scarring. Murine models of human burns have been developed, but the inflammatory response to injury in these models has not been well defined. The aim of this study was to profile inflammatory cell populations and gene expression relative to healing and scarring in a murine model of thermal burns. Cutaneous injuries were created on the dorsal region of C57Bl/6 mice using a heated metal rod. Animals were euthanized at selected time points over ten weeks, with the lesions evaluated using macroscopic measurements, histology, immunofluorescent histochemistry and quantitative PCR. The burn method generated a reproducible, partial-thickness injury that healed within two weeks through both contraction and re-epithelialization, in a manner similar to human burns. The injury caused an immediate increase in pro-inflammatory cytokine and chemokine expression, coinciding with an influx of neutrophils, and the disappearance of Langerhans cells and mast cells. This preceded an influx of dendritic cells and macrophages, a quarter of which displayed an inflammatory (M1) phenotype, with both populations peaking at closure. As with human burns, the residual scar increased in size, epidermal and dermal thickness, and mast cell numbers over 10 weeks, but abnormal collagen I-collagen III ratios, fibre organization and macrophage populations resolved 3–4 weeks after closure. Characterisation of the inflammatory response in this promising murine burn model will assist future studies of burn complications and aid in the preclinical testing of new anti-inflammatory and anti-scarring therapies.

Sign in / Sign up

Export Citation Format

Share Document