scholarly journals Capping Amyloid β-Sheets of the Tau-Amyloid Structure VQIVYK with Hexapeptides Designed To Arrest Growth. An ONIOM and Density Functional Theory Study

2014 ◽  
Vol 118 (12) ◽  
pp. 3326-3334 ◽  
Author(s):  
Joshua A. Plumley ◽  
Jorge Ali-Torres ◽  
Gabor Pohl ◽  
J. J. Dannenberg
Author(s):  
Christina Liu ◽  
Xuan Luo

The onset of Alzheimer's disease (AD) is caused by amyloid-β (Aβ) aggregation. Elevated levels of metals, specifically copper, zinc, iron, and aluminum, accumulate in senile Aβ plaque deposits, disrupting normal...


Biochemistry ◽  
2012 ◽  
Vol 51 (27) ◽  
pp. 5387-5393 ◽  
Author(s):  
Dipankar Roy ◽  
Gabor Pohl ◽  
Jorge Ali-Torres ◽  
Mateusz Marianski ◽  
J. J. Dannenberg

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