Intersubunit Communication via Changes in Hemoglobin Quaternary Structures Revealed by Time-Resolved Resonance Raman Spectroscopy: Direct Observation of the Perutz Mechanism

2013 ◽  
Vol 117 (41) ◽  
pp. 12461-12468 ◽  
Author(s):  
Kenta Yamada ◽  
Haruto Ishikawa ◽  
Misao Mizuno ◽  
Naoya Shibayama ◽  
Yasuhisa Mizutani
2018 ◽  
Vol 20 (5) ◽  
pp. 3363-3372 ◽  
Author(s):  
Shanyan Chang ◽  
Misao Mizuno ◽  
Haruto Ishikawa ◽  
Yasuhisa Mizutani

We elucidated the coupling between tertiary and quaternary structural dynamics in human adult hemoglobin using time-resolved resonance Raman spectroscopy.


Author(s):  
Robert Wilbrandt ◽  
Niels-Henrik Jensen ◽  
C. Houée-Levin ◽  
R. V. Bensasson

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