scholarly journals Side-by-Side Comparison of DNA Damage Induced by Low-Energy Electrons and High-Energy Photons with Solid TpTpT Trinucleotide

2013 ◽  
Vol 117 (35) ◽  
pp. 10122-10131 ◽  
Author(s):  
Yeunsoo Park ◽  
Anita R. Peoples ◽  
Guru S. Madugundu ◽  
Léon Sanche ◽  
J. Richard Wagner
Keyword(s):  
Dna Damage ◽  
High Energy ◽  
Low Energy ◽  
Low Energy Electrons

scholarly journals Symmetric and triangle-shaped variability of blazars

2014 ◽  
Vol 10 (S313) ◽  
pp. 97-98
Author(s):  
Kenji Yoshida
Keyword(s):  
Gamma Ray ◽  
High Energy ◽  
Low Energy ◽  
Light Curves ◽  
X Ray ◽  
High Energy Electrons ◽  
Flux Variability ◽  
Low Energy Electrons ◽  
Flux Increase ◽  
Rise Phase

AbstractSymmetric and triangle-shaped flux variability in X-ray and gamma-ray light curves is observed from many blazars. We derived the X-ray spectrum changing in time by using a kinetic equation of high energy electrons. Giving linearly changing the injection of low energy electrons into accelerating and emitting region, we obtained the preliminary results that represent the characteristic X-ray variability of the linear flux increase with hardening in the rise phase and the linear decrease with softening in the decay phase.

On Lensless Imaging of Organics with Neutrons, X-Rays, Helium Atoms and Low Energy Electrons: Damage and Iterative Phase Retrieval

2001 ◽  
Vol 7 (S2) ◽  
pp. 268-269
Author(s):  
J.C.H. Spence ◽  
U. Weierstall ◽  
J. Fries
Keyword(s):  
Phase Retrieval ◽  
Iterative Algorithms ◽  
High Energy ◽  
Low Energy ◽  
X Rays ◽  
Noise Sources ◽  
Helium Atoms ◽  
High Energy Electrons ◽  
Elastic Event ◽  
Low Energy Electrons

Recent experiments with X-rays and high energy electrons have shown that image recovery from diffracted intensities is possible for non-periodic objects using iterative algorithms. Application of these methods to biological molecules raises the crucial problem of radiation damage, which may be quantified by Q = ΔE σi/σe, the amount of energy deposited by inelastic events per elastic event. Neutrons, helium atoms and low energy electrons below most ionization thresholds produce the smallest values of Q (see for TMV imaged at 60 eV). For neutrons (λ = 10-2Å, and deuterated, 15N-abelled molecules) Q is ∼3000 times smaller (∼50 times for λ = 1.8Å) than for electrons (80- 500keV) and about 4x 106 times smaller than for soft X-rays (1.5Å). Since σe for neutrons is about 105 times smaller than for electrons (and about 10 times smaller than for soft X-rays), a 105 times higher neutron dose is required to obtain the same S/N in a phase contrast image compared with electrons, if other noise sources are absent.

DNA Damage Induced by Low-Energy Electrons: Conversion of Thymine to 5,6-Dihydrothymine in the Oligonucleotide Trimer TpTpT

2011 ◽  
Vol 175 (2) ◽  
pp. 240-246 ◽  
Author(s):  
Yeunsoo Park ◽  
Zejun Li ◽  
Pierre Cloutier ◽  
Léon Sanche ◽  
J. Richard Wagner
Keyword(s):  
Dna Damage ◽  
Low Energy ◽  
Low Energy Electrons

The role of low-energy electrons in the high-energy radiolysis of condensed CF3I

2010 ◽  
Vol 22 (8) ◽  
pp. 084006 ◽  
Author(s):  
Mahesh Rajappan ◽  
Lin L Zhu ◽  
Jizhou Wang ◽  
Graeme Gardner ◽  
Kevin Bu ◽  
...  
Keyword(s):  
High Energy ◽  
Low Energy ◽  
Low Energy Electrons

scholarly journals Can Low-Energy Electrons Affect High-Energy Physics Accelerators?

2004 ◽  
Vol 93 (1) ◽  
Author(s):  
R. Cimino ◽  
I. R. Collins ◽  
M. A. Furman ◽  
M. Pivi ◽  
F. Ruggiero ◽  
...  
Keyword(s):  
High Energy Physics ◽  
High Energy ◽  
Low Energy ◽  
Low Energy Electrons ◽  
Energy Physics

scholarly journals The Role of Low-Energy Electron Interactions in cis-Pt(CO)2Br2 Fragmentation

2021 ◽  
Vol 22 (16) ◽  
pp. 8984
Author(s):  
Maicol Cipriani ◽  
Styrmir Svavarsson ◽  
Filipe Ferreira da Silva ◽  
Hang Lu ◽  
Lisa McElwee-White ◽  
...  
Keyword(s):  
Coordination Compound ◽  
Electron Attachment ◽  
High Energy ◽  
Low Energy ◽  
Carbonyl Complexes ◽  
Secondary Electrons ◽  
High Energy Radiation ◽  
Low Energy Electrons ◽  
In Cis

Platinum coordination complexes have found wide applications as chemotherapeutic anticancer drugs in synchronous combination with radiation (chemoradiation) as well as precursors in focused electron beam induced deposition (FEBID) for nano-scale fabrication. In both applications, low-energy electrons (LEE) play an important role with regard to the fragmentation pathways. In the former case, the high-energy radiation applied creates an abundance of reactive photo- and secondary electrons that determine the reaction paths of the respective radiation sensitizers. In the latter case, low-energy secondary electrons determine the deposition chemistry. In this contribution, we present a combined experimental and theoretical study on the role of LEE interactions in the fragmentation of the Pt(II) coordination compound cis-PtBr2(CO)2. We discuss our results in conjunction with the widely used cancer therapeutic Pt(II) coordination compound cis-Pt(NH3)2Cl2 (cisplatin) and the carbonyl analog Pt(CO)2Cl2, and we show that efficient CO loss through dissociative electron attachment dominates the reactivity of these carbonyl complexes with low-energy electrons, while halogen loss through DEA dominates the reactivity of cis-Pt(NH3)2Cl2.

scholarly journals Microdosimetric calculations of the direct DNA damage induced by low energy electrons using the Geant4-DNA Monte Carlo code

2020 ◽  
Vol 65 (4) ◽  
pp. 045007 ◽  
Author(s):  
Stefanos Margis ◽  
Maria Magouni ◽  
Ioanna Kyriakou ◽  
Alexandros G Georgakilas ◽  
Sebastien Incerti ◽  
...  
Keyword(s):  
Dna Damage ◽  
Monte Carlo ◽  
Low Energy ◽  
Monte Carlo Code ◽  
Low Energy Electrons
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