The Influence of Solutes on the Enthalpy/Entropy Change of the Actinomycin D Binding to DNA: Hydration, Energy Compensation and Long-Range Deformation on DNA

2011 ◽  
Vol 115 (28) ◽  
pp. 8883-8890 ◽  
Author(s):  
André L. Galo ◽  
João Rugiero Neto ◽  
Dulcinea P. Brognaro ◽  
Renato C. Caetano ◽  
Fátima P. Souza ◽  
...  
Keyword(s):  
Long Range ◽  
Actinomycin D ◽  
Entropy Change ◽  
Hydration Energy ◽  
Dna Hydration ◽  
Energy Compensation

scholarly journals Long-Range Atomic Order and Entropy Change at the Martensitic Transformation in a Ni-Mn-In-Co Metamagnetic Shape Memory Alloy

Entropy ◽  
2014 ◽  
Vol 16 (5) ◽  
pp. 2756-2767 ◽  
Author(s):  
Vicente Sánchez-Alarcos ◽  
Vicente Recarte ◽  
José Pérez-Landazábal ◽  
Eduard Cesari ◽  
José Rodríguez-Velamazán
Keyword(s):  
Martensitic Transformation ◽  
Shape Memory Alloy ◽  
Shape Memory ◽  
Long Range ◽  
Entropy Change ◽  
Atomic Order ◽  
Range Atomic Order

The analysis of magnetic entropy change and long-range ferromagnetic order in Mn1−xAgxCoGe

2018 ◽  
Vol 54 (4) ◽  
pp. 3196-3210 ◽  
Author(s):  
Xiaodong Si ◽  
Yongsheng Liu ◽  
Xinxiu Ma ◽  
Jia Lin ◽  
Jie Yang ◽  
...  
Keyword(s):  
Long Range ◽  
Magnetic Entropy Change ◽  
Entropy Change ◽  
Magnetic Entropy ◽  
Ferromagnetic Order

Effect of Some Metabolic Inhibitors on Vinblastine-Induced Ribosomal-Granular Material Complexes

1971 ◽  
Vol 29 ◽  
pp. 548-549
Author(s):  
Awtar Krishan ◽  
Dora Hsu
Keyword(s):  
Granular Material ◽  
Rna Synthesis ◽  
Culture Medium ◽  
Actinomycin D ◽  
Metabolic Inhibitors ◽  
Protein And Rna Synthesis ◽  
Apparent Reduction ◽  
Plant Alkaloids ◽  
In Cells

Cells exposed to antitumor plant alkaloids, vinblastine and vincristine sulfate have large proteinacious crystals and complexes of ribosomes, helical polyribosomes and electron-dense granular material (ribosomal complexes) in their cytoplasm, Binding of H3-colchicine by the in vivo crystals shows that they contain microtubular proteins. Association of ribosomal complexes with the crystals suggests that these structures may be interrelated.In the present study cultured human leukemic lymphoblasts (CCRF-CEM), were incubated with protein and RNA-synthesis inhibitors, p. fluorophenylalanine, puromycin, cycloheximide or actinomycin-D before the addition of crystal-inducing doses of vinblastine to the culture medium. None of these compounds could completely prevent the formation of the ribosomal complexes or the crystals. However, in cells pre-incubated with puromycin, cycloheximide, or actinomycin-D, a reduction in the number and size of the ribosomal complexes was seen. Large helical polyribosomes were absent in the ribosomal complexes of cells treated with puromycin, while in cells exposed to cycloheximide, there was an apparent reduction in the number of ribosomes associated with the ribosomal complexes (Fig. 2).

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