Investigations on the Interactions between Plasma Proteins and Magnetic Iron Oxide Nanoparticles with Different Surface Modifications

2010 ◽  
Vol 114 (49) ◽  
pp. 21270-21276 ◽  
Author(s):  
Shujie Liu ◽  
Yuchun Han ◽  
Ruirui Qiao ◽  
Jianfeng Zeng ◽  
Qiaojuan Jia ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Plasma Proteins ◽  
Surface Modifications ◽  
Oxide Nanoparticles ◽  
Magnetic Iron Oxide Nanoparticles ◽  
Magnetic Iron Oxide

scholarly journals Multifunctional magnetic iron oxide nanoparticles: diverse synthetic approaches, surface modifications, cytotoxicity towards biomedical and industrial applications

BMC Materials ◽  
2019 ◽  
Vol 1 (1) ◽  
Author(s):  
Subramanian Natarajan ◽  
Kannan Harini ◽  
Gnana Prakash Gajula ◽  
Bruno Sarmento ◽  
Maria Teresa Neves-Petersen ◽  
...  
Keyword(s):  
Surface Modification ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Surface Modifications ◽  
Synthetic Methods ◽  
Biomedical Science ◽  
Oxide Nanoparticles ◽  
Magnetic Iron Oxide Nanoparticles ◽  
Cytotoxic Effects ◽  
Magnetic Iron Oxide

AbstractMagnetic iron oxide nanoparticles (MIONPs) play a major role in the emerging fields of nanotechnology to facilitate rapid advancements in biomedical and industrial platforms. The superparamagnetic properties of MIONPs and their environment friendly synthetic methods with well-defined particle size have become indispensable to obtain their full potential in a variety of applications ranging from cellular to diverse areas of biomedical science. Thus, the broadened scope and need for MIONPs in their demanding fields of applications required to be highlighted for a comprehensive understanding of their state-of-the-art. Many synthetic methods, however, do not entirely abolish their undesired cytotoxic effects caused by free radical production and high iron dosage. In addition, the agglomeration of MIONPs has also been a major problem. To alleviate these issues, suitable surface modification strategies adaptive to MIONPs has been suggested not only for the effective cytotoxicity control but also to minimize their agglomeration. The surface modification using inorganic and organic polymeric materials would represent an efficient strategy to utilize the diagnostic and therapeutic potentials of MIONPs in various human diseases including cancer. This review article elaborates the structural and magnetic properties of MIONPs, specifically magnetite, maghemite and hematite, followed by the important synthetic methods that can be exploited for biomedical approaches. The in vivo cytotoxic effects and the possible surface modifications employed to eliminate the cytotoxicity thereby enhancing the nanoparticle efficacy are also critically discussed. The roles and applications of surface modified MIONPs in medical and industrial platforms have been described for the benefits of global well-being.

Superparamagnetic nanocomposites obtained by dispersion of ultrafine magnetic iron oxide nanoparticles in poly(3-hydroxybutyrate)

2014 ◽  
Vol 55 ◽  
pp. 160-169 ◽  
Author(s):  
David D’Amico ◽  
Laura A. Fasce ◽  
Cristina E. Hoppe ◽  
M. Arturo López-Quintela ◽  
Viviana P. Cyras
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Magnetic Iron Oxide Nanoparticles ◽  
Magnetic Iron Oxide
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