The Influence of Sodium Perfluorooctanoate on the Conformational Transitions of Human Immunoglobulin

2007 ◽  
Vol 111 (28) ◽  
pp. 8045-8052 ◽  
Author(s):  
Paula V. Messina ◽  
Gerardo Prieto ◽  
Francisco Salgado ◽  
Carla Varela ◽  
Montserrat Nogueira ◽  
...  
Keyword(s):  
Conformational Transitions ◽  
Human Immunoglobulin ◽  
Sodium Perfluorooctanoate

A Potentiometric and Spectroscopic Study on the Interaction Between Human Immunoglobulin G and Sodium Perfluorooctanoate in Aqueous Solution

2007 ◽  
Vol 251 (1) ◽  
pp. 103-111
Author(s):  
Paula V. Messina ◽  
Gerardo Prieto ◽  
Juan Sabín ◽  
Elena Blanco ◽  
Carla Varela ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Spectroscopic Study ◽  
Immunoglobulin G ◽  
Human Immunoglobulin ◽  
Human Immunoglobulin G ◽  
Sodium Perfluorooctanoate

Conformational Transitions in Escherichia coli Ribosomal RNAs as Visualized by Dedicated STEM

1988 ◽  
Vol 46 ◽  
pp. 176-177
Author(s):  
J.S. Wall ◽  
V. Maridiyan ◽  
S. Tumminia ◽  
J. Hairifeld ◽  
M. Boublik
Keyword(s):  
Ionic Strength ◽  
Three Dimensional ◽  
Conformational Transitions ◽  
Dark Field ◽  
Dimensional Structure ◽  
Ribosomal Rnas ◽  
Field Mode ◽  
Freeze Dried ◽  
High Resolution Images ◽  
Low Ionic Strength

The high contrast in the dark-field mode of dedicated STEM, specimen deposition by the wet film technique and low radiation dose (1 e/Å2) at -160°C make it possible to obtain high resolution images of unstained freeze-dried macromolecules with minimal structural distortion. Since the image intensity is directly related to the local projected mass of the specimen it became feasible to determine the molecular mass and mass distribution within individual macromolecules and from these data to calculate the linear density (M/L) and the radii of gyration.2 This parameter (RQ), reflecting the three-dimensional structure of the macromolecular particles in solution, has been applied to monitor the conformational transitions in E. coli 16S and 23S ribosomal RNAs in solutions of various ionic strength.In spite of the differences in mass (550 kD and 1050 kD, respectively), both 16S and 23S RNA appear equally sensitive to changes in buffer conditions. In deionized water or conditions of extremely low ionic strength both appear as filamentous structures (Fig. la and 2a, respectively) possessing a major backbone with protruding branches which are more frequent and more complex in 23S RNA (Fig. 2a).

Conformational transitions and dynamics of thermal responsive poly(N-isopropylacrylamide) polymers as revealed by molecular simulation

2014 ◽  
Vol 55 ◽  
pp. 153-159 ◽  
Author(s):  
Ming S. Liu ◽  
Cheryl Taylor ◽  
Bill Chong ◽  
Lihui Liu ◽  
Ante Bilic ◽  
...  
Keyword(s):  
Molecular Simulation ◽  
Conformational Transitions

Cleavage of Human Immunoglobulin G by Treponema denticola

Anaerobe ◽  
2001 ◽  
Vol 7 (1) ◽  
pp. 1-4 ◽  
Author(s):  
Daniel Grenier ◽  
Denis Mayrand
Keyword(s):  
Immunoglobulin G ◽  
Human Immunoglobulin ◽  
Treponema Denticola ◽  
Human Immunoglobulin G

Treatment of acute idiopathic polyradiculoneuritis with intravenous human immunoglobulin therapy

2020 ◽  
Vol 11 (9) ◽  
pp. 426-431
Author(s):  
Emily Hooper
Keyword(s):  
Nursing Care ◽  
Immunoglobulin Therapy ◽  
Human Immunoglobulin ◽  
Nursing Interventions ◽  
Veterinary Hospital

The patient was presented to a veterinary hospital with acute progressive onset of non-ambulatory tetraparesis. An appropriate diagnosis of acute idiopathic polyradiculoneuritis was made and suitable supportive nursing care implemented. The patient was later diagnosed with pneumonia as a consequence of prolonged recumbency, requiring further nursing interventions. Treatment with intravenous human immunoglobulin therapy was subsequently initiated and the patient improved but was sadly later euthanased.

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