Structure of Mixed Carboxylic Acid Terminated Self-Assembled Monolayers:  Experimental and Theoretical Investigation

2007 ◽  
Vol 111 (11) ◽  
pp. 4294-4304 ◽  
Author(s):  
M. L. Carot ◽  
V. A. Macagno ◽  
P. Paredes-Olivera ◽  
E. M. Patrito
Keyword(s):  
Carboxylic Acid ◽  
Theoretical Investigation ◽  
Self Assembled Monolayers ◽  
Assembled Monolayers ◽  
Self Assembled

Comparison of Proliferation and Growth of Human Keratinocytes on Plasma CO-Polymers of Acrylic acid/1,7- Octadiene and Self Assembled Monolayers

1998 ◽  
Vol 544 ◽  
Author(s):  
D. B. Haddow ◽  
R. M. France ◽  
R. D. Short ◽  
S. Macneil ◽  
R. A. Dawson
Keyword(s):  
Cell Proliferation ◽  
Tissue Culture ◽  
Carboxylic Acid ◽  
Cell Attachment ◽  
Human Keratinocytes ◽  
Collagen I ◽  
Self Assembled Monolayers ◽  
Self Assembled Monolayer ◽  
Assembled Monolayers ◽  
Self Assembled

AbstractHuman keratinocytes have been cultured on plasma co-polymers (PCPs), self assembled monolayers (SAMs), tissue culture poly(styrene) (TCPS) and collagen I. The degree of keratinocyte attachment was measured over 24 hours and cell proliferation and growth monitored over 7 days using optical microscopy and DNA concentrations. Cell attachment and proliferation and growth on the PCP surfaces were compared with 2 self assembled monolayer (SAM) systems. PCP surfaces containing carboxylic acid functionalities promoted keratinocyte attachment, with optimum attachment levels seen on surfaces containing less than 5% acid groups. The level of attachment on these surfaces was comparable to that seen on collagen I, a preferred substratum for the culturing of keratinocytes. After several days in culture the cells were well attached and proliferative. Keratinocytes attached well to acidterminated SAMs but attached poorly to methyl-terminated SAMs.

Influence of Gold Topography on Carboxylic Acid Terminated Self-Assembled Monolayers

Langmuir ◽  
2002 ◽  
Vol 18 (4) ◽  
pp. 978-980 ◽  
Author(s):  
Michael C. Leopold ◽  
Joseph A. Black ◽  
Edmond F. Bowden
Keyword(s):  
Carboxylic Acid ◽  
Self Assembled Monolayers ◽  
Assembled Monolayers ◽  
Self Assembled
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