Novel Method to Prepare Morphologically Rich Polymeric Surfaces for Biomedical Applications via Phase Separation and Arrest of Microgel Particles

2006 ◽  
Vol 110 (30) ◽  
pp. 14581-14589 ◽  
Author(s):  
Iseult Lynch ◽  
Ian Miller ◽  
William M. Gallagher ◽  
Kenneth A. Dawson
Keyword(s):  
Phase Separation ◽  
Biomedical Applications ◽  
Polymeric Surfaces ◽  
Microgel Particles ◽  
Novel Method

Producing PVP Nanofibers by Electrospinning in N2

2012 ◽  
Vol 560-561 ◽  
pp. 701-708 ◽  
Author(s):  
Lu Li ◽  
Jie Xu ◽  
Tao Fang ◽  
Jin Geng ◽  
Detlef Freitag ◽  
...  
Keyword(s):  
Mass Transfer ◽  
Phase Equilibrium ◽  
Phase Separation ◽  
Phase Behavior ◽  
Polymer Solution ◽  
Aspen Plus ◽  
Good Choice ◽  
The Other ◽  
Binary Phase ◽  
Novel Method

Electrospinning combined with nonsolvent-induced phase separation is a simple and novel method to produce porous nanofibers. In the study, Poly (vinylpyrrolidone) (PVP) nanofibers were fabricated using an electrospinning approach complemented by compressed nitrogen (N). N2 was used as the nonsolvent of choice. Besides, the tun2ning of N2 pressure and temperature can impact the nanofibers’ morphologies by altering phase behavior and mass transfer. Also, the other parameters affecting electrospinning of polymer solution were discussed. The results were demonstrated by extending the technique to PVP/dichloromethane (DCM) and PVP/ethanol (EtOH) systems. And the binary phase equilibrium of solvents (dichloromethane or ethanol) and N simulated by ASPEN PLUS 2006 demonstrates that N is not a 2good choice for producing hollow or po2rous polymer nanofibers.

Localized Microstructures Fabrication Through Standing Surface Acoustic Wave and User-Defined Waveguides

2019 ◽  
Author(s):  
Yancheng Wang ◽  
Chenyang Han ◽  
Deqing Mei ◽  
Chengyao Xu
Keyword(s):  
Acoustic Wave ◽  
Surface Acoustic Wave ◽  
Structural Design ◽  
Acoustic Waves ◽  
Biomedical Applications ◽  
Cell Interaction ◽  
Experimental Setup ◽  
Acoustic Waveguides ◽  
Novel Method ◽  
Patterned Microstructure

Abstract Polymer-based substrates with patterned microstructure on the surfaces, e.g., cell culturing scaffolds, have been utilized in biomedical applications. This paper develops a novel method to fabricate the localized microstructure on the polymer-based substrate with the assistance of standing surface acoustic wave (SAW) and user-defined acoustic waveguides. The specific designed acoustic waveguides can localize the standing acoustic waves and transmit to the liquid film and excite patterned microstructures on the surface, then using ultraviolet (UV) to solidify the substrate with patterned microstructures. The structural design and fabrication of the SAW device and three different shaped acoustic waveguides are presented. Then, experimental setup and procedures to verify the polymer-substrate with localized microstructures fabrication are performed. By using the different shape of the acoustic waveguides, several types of patterned microstructures with different morphologies are successfully fabricated. Results demonstrated that the proposed fabrication method is an effective way to fabricate polymer-based substrate with localized patterned microstructures, which may have potential in the research on tissue engineering, cell-cell interaction, and other biomedical applications.

Nanofibres and their Influence on Cells for Tissue Regeneration

2005 ◽  
Vol 58 (10) ◽  
pp. 704 ◽  
Author(s):  
Yanping Karen Wang ◽  
Thomas Yong ◽  
Seeram Ramakrishna
Keyword(s):  
Phase Separation ◽  
Cell Growth ◽  
Tissue Regeneration ◽  
Self Assembly ◽  
Biomedical Applications ◽  
Synthetic Polymer ◽  
Biocompatible Polymers ◽  
Mechanical Methods ◽  
The Matrix ◽  
Cell Growth And Proliferation

Synthetic polymer and biopolymer nanofibres can be fabricated through self-assembly, phase separation, electrospinning, and mechanical methods. These novel functional biocompatible polymers are very promising for a variety of future biomedical applications. There are many characteristics of nanofibres that would potentially influence cell growth and proliferation. As such, many studies have been carried out to elucidate the cell–nanofibre interaction with the purpose of optimizing the matrix for cell growth and tissue regeneration. In this Review, we present current literatures and our research on the interactions between cells and nanofibres, and the potentials of nanofibre scaffolds for biomedical applications.

Sassolite Formation in Glass Powders: A Novel Method to Study Phase Separation in Alkali Borosilicate Glass Compositions

2010 ◽  
Vol 93 (10) ◽  
pp. 3027-3030 ◽  
Author(s):  
C. J. Dileep Kumar ◽  
M. A. Shadiya ◽  
E. K. Sunny ◽  
N. Raghu ◽  
N. Venkataramani ◽  
...  
Keyword(s):  
Phase Separation ◽  
Borosilicate Glass ◽  
Study Phase ◽  
Novel Method ◽  
Glass Compositions ◽  
Glass Powders

In Situ Growth of Carbon Nanotubes in Hydroxyapatite Matrix by Chemical Vapor Deposition

2009 ◽  
Vol 79-82 ◽  
pp. 1671-1674 ◽  
Author(s):  
Xiao Ying Lu ◽  
Hao Wang ◽  
Sheng Yi Xia ◽  
Jian Xin Wang ◽  
Jie Weng
Keyword(s):  
Mechanical Properties ◽  
Carbon Nanotubes ◽  
Chemical Vapor Deposition ◽  
Vapor Deposition ◽  
Biomedical Applications ◽  
Chemical Vapor ◽  
Novel Method ◽  
Biomedical Fields ◽  
Walled Cnts

Carbon nanotubes (CNTs)/hydroxyapatite (HA) nanocomposites have been successfully fabricated by a novel method for the biomedical applications, which is in situ growing CNTs in HA matrix in a chemical vapor deposition (CVD) system. The results show that it is feasible to in situ grow CNTs in HA matrix by CVD for the fabrication of CNTs/HA nanocomposites. Multi-walled CNTs with 50-80 nm in diameter have been grown in situ from HA matrix with the pretreatment of sintering at 1473K in air. The nanocomposites are composed with carbon crystals in CNTs form, HA crystallites and calcium phosphate crystallites, one of most important CaP bioceramics. And the CNTs content is about 1% proportion by weight among the composites in our experiments, which can enhance the HA mechanical properties and the CNTs content does not affect the HA performances. These CNTs/HA nanocomposites have the potential application in the biomedical fields.

A novel method to fabricate silica nanotubes based on phase separation effect

2010 ◽  
Vol 20 (41) ◽  
pp. 9068 ◽  
Author(s):  
Wei Wang ◽  
Jinyuan Zhou ◽  
Shanshan Zhang ◽  
Jie Song ◽  
Huigao Duan ◽  
...  
Keyword(s):  
Phase Separation ◽  
Silica Nanotubes ◽  
Separation Effect ◽  
Novel Method

Comparing colloidal phase separation induced by linear polymer and by microgel particles

Soft Matter ◽  
2011 ◽  
Vol 7 (21) ◽  
pp. 10345 ◽  
Author(s):  
K. Bayliss ◽  
J. S. van Duijneveldt ◽  
M. A. Faers ◽  
A. W. P. Vermeer
Keyword(s):  
Phase Separation ◽  
Linear Polymer ◽  
Microgel Particles

Fullerene Based Nanomaterials for Biomedical Applications: Engineering, Functionalization and Characterization

2013 ◽  
Vol 633 ◽  
pp. 224-238 ◽  
Author(s):  
Lidija Matija ◽  
Roumiana Tsenkova ◽  
Jelena Munćan ◽  
Mari Miyazaki ◽  
Kyoko Banba ◽  
...  
Keyword(s):  
Infrared Spectroscopy ◽  
Near Infrared Spectroscopy ◽  
Biomedical Applications ◽  
Near Infrared ◽  
Biological Properties ◽  
Cage Structure ◽  
Carbon Cage ◽  
Novel Method ◽  
Medicine Analysis ◽  
New Skin

Since their discovery in 1985, fullerenes have attracted considerable attention. Their unique carbon cage structure provides numerous opportunities for functionalization, giving this nanomaterial great potential for applications in the field of medicine. Analysis of the chemical, physical, and biological properties of fullerenes and their derivatives showed promising results. In this study, functionalized fullerene based nanomaterials were characterized using near infrared spectroscopy, and a novel method - Aquaphotomics. These nanomaterials were then used for engineering a new skin cream formula for their application in cosmetics and medicine. In this paper, results of nanocream effects on the skin (using near infrared spectroscopy and aquaphotomics), and existing results of biocompatibility and cytotoxicity of fullerene base nanomaterials, are presented.

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