Blocking of the Nicotinic Acetylcholine Receptor Ion Channel by Chlorpromazine, a Noncompetitive Inhibitor:  A Molecular Dynamics Simulation Study

Yechun Xu; Francisco J. Barrantes; Jianhua Shen; Xiaomin Luo; Weiliang Zhu; Kaixian Chen; Hualiang Jiang

doi:10.1021/jp0604591

Blocking of the Nicotinic Acetylcholine Receptor Ion Channel by Chlorpromazine, a Noncompetitive Inhibitor: A Molecular Dynamics Simulation Study

The Journal of Physical Chemistry B ◽

10.1021/jp0604591 ◽

2006 ◽

Vol 110 (41) ◽

pp. 20640-20648 ◽

Cited By ~ 10

Author(s):

Yechun Xu ◽

Francisco J. Barrantes ◽

Jianhua Shen ◽

Xiaomin Luo ◽

Weiliang Zhu ◽

...

Keyword(s):

Molecular Dynamics ◽

Molecular Dynamics Simulation ◽

Ion Channel ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Simulation Study ◽

Dynamics Simulation ◽

Nicotinic Acetylcholine ◽

Noncompetitive Inhibitor

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Structural effects of divalent calcium cations on the α7 nicotinic acetylcholine receptor: A molecular dynamics simulation study

Proteins Structure Function and Bioinformatics ◽

10.1002/prot.25761 ◽

2019 ◽

Vol 87 (11) ◽

pp. 992-1005

Author(s):

Abishek Suresh ◽

Andrew Hung

Keyword(s):

Molecular Dynamics ◽

Molecular Dynamics Simulation ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Simulation Study ◽

Dynamics Simulation ◽

Structural Effects ◽

Α7 Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

Calcium Cations

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Correction to “Conformational Dynamics of the Nicotinic Acetylcholine Receptor Channel: A 35-ns Molecular Dynamics Simulation Study”

Journal of the American Chemical Society ◽

10.1021/jacs.5b02329 ◽

2015 ◽

Vol 137 (11) ◽

pp. 3992-3992 ◽

Cited By ~ 1

Author(s):

Yechun Xu ◽

Francisco J. Barrantes ◽

Xiaomin Luo ◽

Kaixian Chen ◽

Jianhua Shen ◽

...

Keyword(s):

Molecular Dynamics ◽

Molecular Dynamics Simulation ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Simulation Study ◽

Conformational Dynamics ◽

Dynamics Simulation ◽

Nicotinic Acetylcholine ◽

Acetylcholine Receptor Channel ◽

Receptor Channel

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Conformational Dynamics of the Nicotinic Acetylcholine Receptor Channel: A 35-ns Molecular Dynamics Simulation Study

Journal of the American Chemical Society ◽

10.1021/ja044577i ◽

2005 ◽

Vol 127 (4) ◽

pp. 1291-1299 ◽

Cited By ~ 52

Author(s):

Yechun Xu ◽

Francisco J. Barrantes ◽

Xiaomin Luo ◽

Kaixian Chen ◽

Jianhua Shen ◽

...

Keyword(s):

Molecular Dynamics ◽

Molecular Dynamics Simulation ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Simulation Study ◽

Conformational Dynamics ◽

Dynamics Simulation ◽

Nicotinic Acetylcholine ◽

Acetylcholine Receptor Channel ◽

Receptor Channel

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Compared structures of the free nicotinic acetylcholine receptor main immunogenic region (MIR) decapeptide and the antibody-bound [A76] MIR analogue: A molecular dynamics simulation from two-dimensional NMR data

Biopolymers ◽

10.1002/(sici)1097-0282(1996)40:5<419::aid-bip1>3.0.co;2-z ◽

1996 ◽

Vol 40 (5) ◽

pp. 419-432 ◽

Cited By ~ 15

Author(s):

Piotr Orlewski ◽

Michel Marraud ◽

Manh-Thong Cung ◽

Vassilios Tsikaris ◽

Maria Sakarellos-Daitsiotis ◽

...

Keyword(s):

Molecular Dynamics ◽

Molecular Dynamics Simulation ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Dynamics Simulation ◽

Two Dimensional ◽

Nicotinic Acetylcholine ◽

Nmr Data ◽

Immunogenic Region

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Boundary lipids of the nicotinic acetylcholine receptor: Spontaneous partitioning via coarse-grained molecular dynamics simulation

Biochimica et Biophysica Acta (BBA) - Biomembranes ◽

10.1016/j.bbamem.2019.01.005 ◽

2019 ◽

Vol 1861 (4) ◽

pp. 887-896 ◽

Cited By ~ 8

Author(s):

Liam Sharp ◽

Reza Salari ◽

Grace Brannigan

Keyword(s):

Molecular Dynamics ◽

Molecular Dynamics Simulation ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Dynamics Simulation ◽

Coarse Grained ◽

Nicotinic Acetylcholine ◽

Coarse Grained Molecular Dynamics

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Three dimensional structure analysis of alpha-conotoxin EI(nicotinic acetylcholine receptor antagonist)by molecular dynamics simulation

Seibutsu Butsuri ◽

10.2142/biophys.41.s102_2 ◽

2001 ◽

Vol 41 (supplement) ◽

pp. S102

Author(s):

M. Matsuo ◽

H. Gouda ◽

N. Yamaotsu ◽

S. Hirono

Keyword(s):

Molecular Dynamics ◽

Molecular Dynamics Simulation ◽

Receptor Antagonist ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Structure Analysis ◽

Three Dimensional ◽

Dynamics Simulation ◽

Dimensional Structure ◽

Nicotinic Acetylcholine

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Molecular Dynamics Simulation of the M2 Helices within the Nicotinic Acetylcholine Receptor Transmembrane Domain: Structure and Collective Motions

Biophysical Journal ◽

10.1529/biophysj.104.052878 ◽

2005 ◽

Vol 88 (5) ◽

pp. 3321-3333 ◽

Cited By ~ 32

Author(s):

Andrew Hung ◽

Kaihsu Tai ◽

Mark S.P. Sansom

Keyword(s):

Molecular Dynamics ◽

Molecular Dynamics Simulation ◽

Domain Structure ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Transmembrane Domain ◽

Dynamics Simulation ◽

Nicotinic Acetylcholine ◽

Collective Motions

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1P-033 Does a non-mechanosensitive ion channel really not open by mechanical force? : A coarse grained molecular dynamics simulation study(Protein:Structure & Function, The 47th Annual Meeting of the Biophysical Society of Japan)

Seibutsu Butsuri ◽

10.2142/biophys.49.s68_4 ◽

2009 ◽

Vol 49 (supplement) ◽

pp. S68

Author(s):

Ken Takahashi ◽

Masahiro Sokabe

Keyword(s):

Molecular Dynamics ◽

Molecular Dynamics Simulation ◽

Ion Channel ◽

Annual Meeting ◽

Simulation Study ◽

Mechanical Force ◽

Dynamics Simulation ◽

Coarse Grained ◽

Biophysical Society ◽

Mechanosensitive Ion Channel

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Molecular dynamics simulation study of nerve ion channel

Materials Today Proceedings ◽

10.1016/j.matpr.2016.04.081 ◽

2016 ◽

Vol 3 (6) ◽

pp. 1828-1834 ◽

Cited By ~ 1

Author(s):

Keka Talukdar ◽

Anil Shantappa

Keyword(s):

Molecular Dynamics ◽

Molecular Dynamics Simulation ◽

Ion Channel ◽

Simulation Study ◽

Dynamics Simulation

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Transmembrane domains of viral ion channel proteins: A molecular dynamics simulation study

Biopolymers ◽

10.1002/(sici)1097-0282(200006)53:7<529::aid-bip1>3.0.co;2-6 ◽

2000 ◽

Vol 53 (7) ◽

pp. 529-538 ◽

Cited By ~ 17

Author(s):

Wolfgang B. Fischer ◽

Lucy R. Forrest ◽

Graham R. Smith ◽

Mark S. P. Sansom

Keyword(s):

Molecular Dynamics ◽

Molecular Dynamics Simulation ◽

Ion Channel ◽

Simulation Study ◽

Transmembrane Domains ◽

Dynamics Simulation ◽

Channel Proteins ◽

Ion Channel Proteins

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