Use of the Dithiasuccinoyl (Dts) Amino Protecting Group for Solid-Phase Synthesis of Protected Peptide Nucleic Acid (PNA) Oligomers1-3

1999 ◽  
Vol 64 (20) ◽  
pp. 7281-7289 ◽  
Author(s):  
Marta Planas ◽  
Eduard Bardají ◽  
Knud J. Jensen ◽  
George Barany
Keyword(s):  
Nucleic Acid ◽  
Peptide Nucleic Acid ◽  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Protecting Group ◽  
Phase Synthesis

An Efficient, Convenient Solid-Phase Synthesis of Amino Acid-Modified Peptide Nucleic Acid Monomers and Oligomers

2006 ◽  
Vol 17 (2) ◽  
pp. 551-558 ◽  
Author(s):  
Baghavathy S. Balaji ◽  
Fabio Gallazzi ◽  
Fang Jia ◽  
Michael R. Lewis
Keyword(s):  
Amino Acid ◽  
Nucleic Acid ◽  
Peptide Nucleic Acid ◽  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Phase Synthesis

Peptide Nucleic Acid Monomers: A Convenient and Efficient Synthetic Approach to Fmoc/Boc Monomers

2012 ◽  
Vol 65 (5) ◽  
pp. 539 ◽  
Author(s):  
Elisse C. Browne ◽  
Steven J. Langford ◽  
Belinda M. Abbott
Keyword(s):  
Nucleic Acid ◽  
Peptide Nucleic Acid ◽  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Cost Effective ◽  
Synthetic Approach ◽  
Phase Synthesis ◽  
Cost Effective Method

A convenient and cost-effective method for the synthesis of Fmoc/Boc-protected peptide nucleic acid monomers is described. The Fmoc/Boc strategy was developed in order to eliminate the solubility issues during peptide nucleic acid solid-phase synthesis, in particular that of the cytosine monomer, that occurred when using the commercialized Bhoc chemistry approach.

Solid-phase synthesis of 4-aminopiperidine analogues using the Alloc protecting group: an investigation of Alloc removal from secondary amines

2001 ◽  
Vol 42 (27) ◽  
pp. 4471-4474 ◽  
Author(s):  
Dolors Fernández-Forner ◽  
Gaspar Casals ◽  
Eloı́sa Navarro ◽  
Hamish Ryder ◽  
Fernando Albericio
Keyword(s):  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Secondary Amines ◽  
Protecting Group ◽  
Phase Synthesis

The tert.-Butyloxycarbonyl-(Boc) Group, a Suitable 2?-OH-Protecting Group in Oligoribonucleotide Solid-Phase Synthesis

1994 ◽  
Vol 336 (3) ◽  
pp. 233-236 ◽  
Author(s):  
G�nter Losse ◽  
Wolfgang Naumann ◽  
Andrea Winkler ◽  
Gabriele S�ptitz
Keyword(s):  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Protecting Group ◽  
Phase Synthesis ◽  
Group A
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