Synthetic Approaches to the Angucycline Antibiotics:  A Concise Entry to the Ring System of PD 116740 and TAN 1085

1996 ◽  
Vol 61 (16) ◽  
pp. 5681-5683 ◽  
Author(s):  
David S. Larsen ◽  
Michael D. O'Shea
Keyword(s):  
Ring System ◽  
Synthetic Approaches ◽  
Angucycline Antibiotics

Diversity-Oriented Synthetic Approaches for Furoindoline: A Review

2019 ◽  
Vol 16 (3) ◽  
pp. 342-368 ◽  
Author(s):  
Ramandeep Kaur ◽  
Yagyesh Kapoor ◽  
Sundeep K. Manjal ◽  
Ravindra K. Rawal ◽  
Kapil Kumar
Keyword(s):  
Rheumatoid Arthritis ◽  
Cancer Cachexia ◽  
Biological Activities ◽  
Ring System ◽  
Synthetic Methods ◽  
Structural Units ◽  
Current Article ◽  
Tetrahydropyranyl Ether ◽  
Synthetic Approaches ◽  
Synthetic Target

The furo [2,3-b] indoline ring system is one of the most important structural units in various natural products. It has been known to have inherent biological activities and is utilized as a synthetic target for a number of natural compounds; therefore, this has contributed to a great demand for the growth of synthetic methods for this ring system. Most important compounds with furoindoline ring system are physovenine, madindoline A and B and makomotindoline etc. These compounds are well known to exhibit biological activity against different diseases such as glaucoma, cancer, cachexia, Castleman’s disease, rheumatoid arthritis, etc. The current article focuses on various synthetic approaches for furoindoline containing compounds and essential furoindoline moiety, such as oxindole-5-O-tetrahydropyranyl ether route etc., and various other diastereoand enantio- controlled approach in a very concise way.

Synthetic Approaches Toward Ecteinascidins. Part 2. Preparation of the ABCDE Ring System of Ecteinascidins Having Characteristic Substituents in Both Benzene Rings.

ChemInform ◽  
2003 ◽  
Vol 34 (50) ◽  
Author(s):  
Naoki Saito ◽  
Ryu-ichi Seki ◽  
Noriko Kameyama ◽  
Rie Sugimoto ◽  
Akinori Kubo
Keyword(s):  
Ring System ◽  
Benzene Rings ◽  
Synthetic Approaches
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