Molecular Tuning of Phenylene-Vinylene Derivatives for Two-Photon Photosensitized Singlet Oxygen Production

2009 ◽  
Vol 74 (23) ◽  
pp. 9094-9104 ◽  
Author(s):  
Christian B. Nielsen ◽  
Jacob Arnbjerg ◽  
Mette Johnsen ◽  
Mikkel Jo̷rgensen ◽  
Peter R. Ogilby
2021 ◽  
Author(s):  
Yan-Qin Huang ◽  
Shan-Shan Jiang ◽  
Li-Xiang Pan ◽  
Rui Zhang ◽  
Kun-Lin Liu ◽  
...  

Water-soluble conjugated polymers (WSCPs) with dual capability of two-photon imaging and singlet oxygen (1O2) production have become one type of the most promising agents in noninvasive imaging guided photodynamic therapy...


2005 ◽  
Vol 70 (18) ◽  
pp. 7065-7079 ◽  
Author(s):  
Christian B. Nielsen ◽  
Mette Johnsen ◽  
Jacob Arnbjerg ◽  
Michael Pittelkow ◽  
Sean P. McIlroy ◽  
...  

2010 ◽  
Vol 12 (18) ◽  
pp. 4656 ◽  
Author(s):  
Elisabetta Collini ◽  
Ilaria Fortunati ◽  
Sara Scolaro ◽  
Raffaella Signorini ◽  
Camilla Ferrante ◽  
...  

ChemPhysChem ◽  
2009 ◽  
Vol 10 (11) ◽  
pp. 1789-1793 ◽  
Author(s):  
Wenbing Li ◽  
Naveen Gandra ◽  
Shavelle N. Courtney ◽  
Ruomei Gao

2016 ◽  
Vol 18 (31) ◽  
pp. 21954-21965 ◽  
Author(s):  
Md. M. Alam ◽  
F. Bolze ◽  
C. Daniel ◽  
L. Flamigni ◽  
C. Gourlaouen ◽  
...  

Diketopyrrolopyrrole–porphyrin conjugates show remarkable NIR emission properties, high two-photon absorption cross-sections and significant singlet oxygen production efficiency.


2007 ◽  
Vol 111 (26) ◽  
pp. 5756-5767 ◽  
Author(s):  
Jacob Arnbjerg ◽  
Martin J. Paterson ◽  
Christian B. Nielsen ◽  
Mikkel Jørgensen ◽  
Ove Christiansen ◽  
...  

2021 ◽  
Vol 22 (12) ◽  
pp. 6618
Author(s):  
Ruth Prieto-Montero ◽  
Alejandro Prieto-Castañeda ◽  
Alberto Katsumiti ◽  
Miren P. Cajaraville ◽  
Antonia R. Agarrabeitia ◽  
...  

BODIPY dyes have recently attracted attention as potential photosensitizers. In this work, commercial and novel photosensitizers (PSs) based on BODIPY chromophores (haloBODIPYs and orthogonal dimers strategically designed with intense bands in the blue, green or red region of the visible spectra and high singlet oxygen production) were covalently linked to mesoporous silica nanoparticles (MSNs) further functionalized with PEG and folic acid (FA). MSNs approximately 50 nm in size with different functional groups were synthesized to allow multiple alternatives of PS-PEG-FA decoration of their external surface. Different combinations varying the type of PS (commercial Rose Bengal, Thionine and Chlorine e6 or custom-made BODIPY-based), the linkage design, and the length of PEG are detailed. All the nanosystems were physicochemically characterized (morphology, diameter, size distribution and PS loaded amount) and photophysically studied (absorption capacity, fluorescence efficiency, and singlet oxygen production) in suspension. For the most promising PS-PEG-FA silica nanoplatforms, the biocompatibility in dark conditions and the phototoxicity under suitable irradiation wavelengths (blue, green, or red) at regulated light doses (10–15 J/cm2) were compared with PSs free in solution in HeLa cells in vitro.


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