Synthesis of γ-Butyrolactams by Photoinduced PhSe Group Transfer Radical Cyclization and Formal Synthesis of (±)-Isocynometrine with Diphenyldiselenide as Promoter

2009 ◽  
Vol 74 (22) ◽  
pp. 8610-8615 ◽  
Author(s):  
Dan Yang ◽  
Gao-Yan Lian ◽  
Hai-Feng Yang ◽  
Jin-Di Yu ◽  
Dan-Wei Zhang ◽  
...  
Keyword(s):  
Radical Cyclization ◽  
Formal Synthesis ◽  
Group Transfer ◽  
Group Transfer Radical Cyclization

Selective Approach toward Multifunctionalized Lactams by Lewis Acid Promoted PhSe Group Transfer Radical Cyclization

2010 ◽  
Vol 75 (10) ◽  
pp. 3232-3239 ◽  
Author(s):  
Jin-Di Yu ◽  
Wei Ding ◽  
Gao-Yan Lian ◽  
Ke-Sheng Song ◽  
Dan-Wei Zhang ◽  
...  
Keyword(s):  
Lewis Acid ◽  
Radical Cyclization ◽  
Group Transfer ◽  
Selective Approach ◽  
Group Transfer Radical Cyclization

ChemInform Abstract: Selective Approach Toward Multifunctionalized Lactams by Lewis Acid Promoted PhSe Group Transfer Radical Cyclization.

ChemInform ◽  
2010 ◽  
Vol 41 (40) ◽  
pp. no-no
Author(s):  
Jin-Di Yu ◽  
Wei Ding ◽  
Gao-Yan Lian ◽  
Ke-Sheng Song ◽  
Dan-Wei Zhang ◽  
...  
Keyword(s):  
Lewis Acid ◽  
Radical Cyclization ◽  
Group Transfer ◽  
Selective Approach ◽  
Group Transfer Radical Cyclization

scholarly journals Expedient Access to Enantiopure Cyclopentanic Natural Products: Total Synthesis of (-)-Cyclonerodiol

2015 ◽  
Vol 10 (1) ◽  
pp. 1934578X1501000
Author(s):  
Carmen Pérez Morales ◽  
M. Mar Herrador ◽  
José F. Quílez del Moral ◽  
Alejandro F. Barrero
Keyword(s):  
Natural Products ◽  
Total Synthesis ◽  
Radical Cyclization ◽  
Formal Synthesis ◽  
Common Precursor ◽  
Enantiospecific Synthesis ◽  
Optically Pure

Following the principles of collective total synthesis, a number of natural products sharing an optically pure, multifunctional, cyclopentanic core were synthesized from a common precursor: plinol A (1). This intermediate was efficiently obtained in only four steps from (-)-linalool (2) using as the key step a Ti(III)-mediated diastereoselective radical cyclization. The feasibility of this approach was confirmed with the expedient enantiospecific synthesis of cyclonerodiol (3), and the formal synthesis of chocol G (4) and piperitone (5).

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