Determination of Basic Strength of Aliphatic Amines through Ion Pair Formation in Some Ionic Liquid Solutions

2009 ◽  
Vol 74 (16) ◽  
pp. 6224-6230 ◽  
Author(s):  
Francesca D’Anna ◽  
Paola Vitale ◽  
Renato Noto
Keyword(s):  
Ionic Liquid ◽  
Ion Pair ◽  
Pair Formation ◽  
Aliphatic Amines ◽  
Ion Pair Formation ◽  
Liquid Solutions ◽  
Basic Strength

Rapid Colorimetric Assay of Trimethoprim and Sulfamethoxazole in Pharmaceuticals

1983 ◽  
Vol 66 (6) ◽  
pp. 1447-1449 ◽  
Author(s):  
Asis K Sanyal ◽  
Dinabandhu Laha
Keyword(s):  
Solvent Extraction ◽  
Colorimetric Assay ◽  
Pharmaceutical Preparations ◽  
Ion Pair ◽  
Pair Formation ◽  
Bromophenol Blue ◽  
Colorimetric Determination ◽  
Ion Pair Formation ◽  
Subsequent Measurement

Abstract A method is described for the direct colorimetric determination of trimethoprim and sulfamethoxazole in pharmaceutical preparations, without prior separation. Estimation of trimethoprim is based on its ion-pair formation with bromophenol blue and subsequent measurement of absorbance of the ionpair at 418 nm. Estimation of sulfamethoxazole is possible without removal of trimethoprim by solvent extraction.

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